Biomedical subjects

A Castanheira-Dinis

Publications and source records attributed to A Castanheira-Dinis.

4 recordsLinked to original sources

PubMed2006

Bilateral nanophthalmos and pigmentary retinal dystrophy--an unusual syndrome.

BACKGROUND: To report the clinical picture of the rare association of nanophthalmos and pigmentary retinal dystrophy and its cataract surgery outcome. METHODS: We report a case of a 60-year-old female who presented with bilateral slowly progressive visual loss. RESULTS: The patient presented with bilateral light perception visual acuity, exotropia, brunescent cataract hindering fundus examination and hypodontia. Ultrasonography revealed bilateral nanophthalmos. A visual-evoked potential was also performed preoperatively. Cataract surgery with +40D IOL implantation was uneventful. Postoperative fundus examination revealed pigmentary retinal dystrophy, confirmed by electrophysiologic tests. Glycosaminoglycan urinary excretion was normal. CONCLUSIONS: Congenital bilateral nanophthalmos may rarely be associated with pigmentary retinal dystrophy. We suggest thorough preoperative evaluation in nanophthalmic eyes for the exclusion of significant features concerning visual prognosis.

Evoked Potentials, Visual↗

PubMed1996

Visual function in neurofibromatosis.

OBJECTIVES: To evaluate the visual function in patients with neurofibromatosis (NF) and to study the etiology and incidence of visual dysfunction associated with NF. PATIENTS AND METHODS: A total of 75 patient with diagnostic criteria for NF were evaluated. Neuro-ophthalmological examination as well as electrophysiological and imaging studies were performed. Special attention was given to the presence of visual dysfunction and to its correlation with the ophthalmic changes that were found. RESULTS: Ocular findings were present in 42 (56%) patients. Visual dysfunction was identified in only 11 (14.7%) patients. Visual acuity decrease was the most prevalent change, being present in eight (72.7%) of patients with visual dysfunction. Nystagmus, strabismus, visual field defects, and color vision defects were also detected. Therapy is also reviewed. The prognosis of the 11 patients with visual dysfunction was unfavorable, and is discussed. CONCLUSION: The prevalence of NF and ophthalmological findings related to it make the problem of visual dysfunction in NF a serious one, deserving of the attention of all ophthalmologists. Clinical examination, associated with complementary diagnostic techniques (mainly imaging studies), allows NF's identification, definition, and therapy. The high prevalence of asymptomatic ocular findings in NF (73.8%) highlights the role of imaging techniques in its evaluation.

Adolescent↗

PubMed1985

Congenital optic disc deformities. A clinical approach.

Different kinds of optic disc deformities are considered in this paper. These optic disc deformities include the tilted disc, the morning glory syndrome, the optic pit and the typical coloboma. All of these optic nerve deformities are probably typical and atypical optic disc colobomas. A clinical approach of these typical and atypical colobomas included different tests: angiography, electrophysiology and psychophysics. The genetic characteristics of these colobomas are considered.

Evoked Potentials, Visual↗

PubMed1977

Electrophysiological studies before and after argon-laser photocoagulation in diabetic retinopathy.

50 eyes with diabetic retinopathy were studied before and after treatment with argon-laser coagulation. After treatment, decreases of the L/D ratios of the EOGs and of the amplitudes of all ERG components were found. The scotopic b waves were more involved than the photopic b waves. The peak times were hardly modified. The dark-adaptation curves were not modified. Interesting was the fact that in the pretreatment findings the EOGs were involved before the ERGs. The decreases of the L/D ratios started when avascular and ischemic zones were seen on fluorescein angiography.

Adult↗