Search PubMed⌕ Search

Biomedical subjects

A Carney

Publications and source records attributed to A Carney.

At least 19 recordsLinked to original sources
PubMed1995

Rwanda.

Explore the source record for details and available documents.

Adolescent↗
PubMed1993

Prevalence of neural tube defects in South Australia, 1966-91: effectiveness and impact of prenatal diagnosis.

OBJECTIVE: To determine trends in total prevalence of neural tube defects in South Australia during 1966-91, the impact of prenatal diagnosis on birth prevalence, and the effectiveness of prenatal screening for neural tube defects in 1986-91. DESIGN: All births and terminations of pregnancy affected by neural tube defects and information on prenatal screening were ascertained from multiple sources including the South Australian perinatal and abortion statistics collections, birth defects register, and state maternal serum alpha fetoprotein screening programme. SETTING: Southern Australia. SUBJECTS: All 1058 births and terminations of pregnancy affected by neural tube defects in 1966-91. MAIN OUTCOME MEASURES: Total prevalence and birth prevalence of individual and all neural tube defects. The proportion of screened cases detected prenatally. RESULTS: Total prevalence of neural tube defects during 1966-91 was 2.01/1000 births with no upward or downward trend. However, birth prevalence fell significantly (by 5.1% a year), with an 84% reduction from 2.29/1000 births in 1966 to 0.35/1000 in 1991 (relative risk = 0.16, 95% confidence interval 0.07 to 0.34). The fall was 96% for anencephaly and 82% for spina bifida. 85% of defects, both open and closed, were detected before 28 weeks' gestation in women screened by serum alpha fetoprotein or mid-trimester ultrasonography, or both, in 1986-91 (99.0% for anencephaly and 75.7% for spina bifida). CONCLUSIONS: While the total prevalence of neural tube defects in South Australia remained stable, prenatal diagnosis and termination of pregnancy resulted in an 84% fall in birth prevalence during 1966-91. Screening detected over four fifths of cases in 1986-91.

Confidence Intervals↗
PubMed1984

The Louisiana Mental Health Client-Outcome Evaluation Project: an initial progress report.

The Louisiana Mental Health Client-Outcome Evaluation Project is assessing the effectiveness of the Schainblatt - Hatry system of client-oriented outcome monitoring as applied to Louisiana CMHC outpatient settings. This system involves incorporating a self-administered mental health questionnaire into the routine center intake procedures and use of a combination mail-out and telephone follow-up data collection method. Follow-up procedures can be operated by a small evaluation staff through the State central office. This initial progress report provides an overview of the instruments and procedures being utilized and discusses results of the project obtained thus far.

Adolescent↗
PubMed1984

Tonal confusions in Thai patients with sensorineural hearing loss.

In a tone language, every syllable or word may have a distinctive pitch pattern as part of its phonemic composition. This study examined the extent and nature of impairment in the perception of phonemic tones by hearing-impaired listeners in Thai, a tone language that has five phonemic tones. Seventy-six subjects were assigned to four listener groups: normal-hearing (n = 21), mild-hearing-loss (n = 21), moderate-hearing-loss (n = 26), and severe-hearing-loss (n = 8). Five Thai words differing only in tone were presented for identification in both natural speech and synthetic speech versions. Results from the phonemic identification tests indicated that tonal identification is affected by the presence of sensorineural hearing loss. In particular, the number and often the type of tonal confusions made by Thai hearing-impaired listeners varied with the extent of hearing loss for both natural and synthetic speech versions. In contrast to previous findings on the patterns of consonant and vowel confusions in hearing-impaired listeners, the patterns of tonal confusions in hearing-impaired listeners can be related to the degree of hearing loss.

Adult↗
PubMed1984

Neural tube defects in Western Australia 1966-81 and a review of Australian data 1942-81.

Cases of neural tube defects born in Western Australia during the years 1966-81 were identified from hospital records and death certificates. The overall rate for the 16 year period was 1.81 cases of neural tube defects per 1000 births. The rate rose and then fell over the 16 years. The initial lower rate may have been due to underascertainment, but the recent dramatic fall is statistically significant and has been observed in other Australian states and other parts of the world. This fall was not accounted for by termination of affected pregnancies before 20 weeks' gestation nor by demographic changes in birth order, father's occupation, or parental country of birth. The birth prevalence of neural tube defects determined in previous Australian studies is reviewed in relation to the recent decline in these disorders.

Australia↗
PubMed1984

Mechanism of hyperglycemia and response to treatment with an inhibitor of fatty acid oxidation in a patient with insulin resistance due to antiinsulin receptor antibodies.

Severe hyperglycemia and insulin resistance due to antiinsulin receptor antibodies developed over a period of 3 months in a 50-yr-old insulin-requiring diabetic patient. The hyperglycemia resulted from overproduction of glucose due to excessive rates of glycogenolysis and gluconeogenesis rather than decreased glucose utilization. Treatment with methyl-2-tetradecylglycidate, an inhibitor of fatty acid oxidation, resulted in a decrease in plasma glucose concentration. This was associated with a decrease in the rate of glucose production due to decreases in both gluconeogenesis and glycogenolysis rates, as well as an increase in the respiratory quotient. Plasma glucose concentrations continued to respond to the drug for the next 2 months until the sudden development of terminal hypoglycemia. The hypoglycemic action of the drug is consistent with the existence of an insulin-independent effect of fatty acid oxidation on glucose metabolism in man.

Adipose Tissue↗
PubMed1981

Urinary undiversion in myelomeningocele patients with an ileal conduit diversion.

Neurogenic bladder in myelomeningocele has been managed until recently by routine ileal conduit urinary diversion. Long-term complications are not uncommon after an ileal conduit and 23 of our patients required major surgical revision during the last 2 years. In 5 patients with an ileal conduit urinary undiversion was performed after excision of the conduit and direct ureteral anastomoses. Over-all progress of these patients has been satisfactory. We conclude that when major surgery is required to correct ileal conduit complications in myelomeningocele, urinary undiversion should be considered in selected cases.

Child↗
PubMed1978

Combination of hormonal and psychological treatment for female sexual unresponsiveness: a comparative study.

Thirty-two couples with the presenting problem of female sexual unresponsiveness were treated in a controlled study using a balanced factorial design. Treatment involved a combination of drug therapy and counselling. Half the subjects received testosterone and half diazepam, half received weekly and half monthly counselling. They were assessed before treatment, at the end of treatment and at six months follow-up. Those receiving testosterone did significantly better on a number of behavioural and attitudinal measures than the diazepam group. There were no notable differences in outcome between the two counselling regimes. There were no undesirable side-effects with the testosterone. Further work is needed to establish the indications for testosterone therapy for unresponsive women.

Adult↗