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Biomedical subjects

A Cardinale

Publications and source records attributed to A Cardinale.

50 records · Page 3Linked to original sources

[Ultrasound-guided percutaneous injection of ethanol in Plummer's adenoma. Our experience with 8 patients].

The authors report their experience in the study of 8 patients showing symptoms of thyroid hyperfunction (Plummer's adenoma) and treated with US-guided percutaneous ethanol injection. The treatment consisted in injecting sterile ethanol in varying amounts (2 to 5 ml) according to nodule size, using a fine needle under US guidance. The patients underwent 3 to 6 injections, according to biochemical (T3-T4-TSH) and scintigraphic findings. Follow-up at 12 months showed regression of clinical symptoms, a trend of hormone levels toward normalization and recovery of previously suppressed parenchymal function. No significant complications were observed, except for a transient thyrotoxic crisis in the patient bearing the largest nodule. The treatment of Plummer's adenoma by means of percutaneous ethanol injection under US guidance appears to provide specific clinical and technical advantages over other conventional treatments.

Adenoma↗

[Condylomata acuminata in childhood: description of a case].

Recent advances in understanding human papillomavirus imply that HPV infections are increasing in both men and women. HPV may cause subclinical disease and play a role in genital tumors. In prepuberal children the problem remains uncommon and can offer a difficult task of management and epidemiologic evaluation.

Anus Neoplasms↗

[Iatrogenic Cushing's syndrome in a patient with complex angiomatosis. Description of a case].

Hemangiomas present to physicians with some of the most difficult treatment problems known to medicine. Many modalities are available but all suffer some degree of complications. The Authors describe a case of Cushing's syndrome after steroid therapy of serious capillary-cavernous hemangiomas. This experience points out treatment problems and need of team management.

Adrenal Cortex Hormones↗

Biologic effects of ultrasound on liver cells of rat embryos.

Experiments on the biologic effects of ultrasound (US) were carried out on rat embryos exposed for 120 s to a US beam showing features similar to those already employed for diagnostic purposes. Electron microscopic investigation of the liver parenchyma of rat embryos confirmed results obtained from adult guinea pigs with the same duration of exposure, i.e. diffuse vacuolization of cytoplasma and varying degrees of mitochondrial damage.

Animals↗

[Experimental studies on possible biological effects of ultrasonic diagnosis: ultrastructural analysis of rat embryo].

Within the limits of a systematic research on the biological effects of the ultrasounds, the authors refer on their personal experience on rat's embrions treated, for 120 seconds, with a ultrasonic beam having the common characteristics used in diagnostic investigations. The ultra-structural studies on the hepatic parenchyma substantially confirm the previous results obtained in the adult cavy, exposed for the same period of time, i.e. a diffuse cytoplasmic vacuolization and an unstable mitochondrial damage. Various suggestions are advanced on the particular sensibility that the mitocondria show because of the ultrasonic action. The authors explain the limits of their experimentation in this specific sector of the scientific research.

Animals↗

[Blepharophimosis, ptosis and epicanthus inversus].

Blepharophimosis, ptosis and epicanthus inversus is a rare well-documented autosomal dominant disorder. Described here is a family with typical features of this syndrome in eleven cases in five generations. Syndrome is discussed and blepharophimosis underlined. Blepharophimosis is also a minor defect in the contest of complex malformation syndromes having different aetiology (mendelian inheritance, chromosomal abnormality, toxic agents). The Authors believe that blepharophimosis, for its clinical evidence, is an important guide sign.

Blepharoptosis↗