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Biomedical subjects

A Caralps

Publications and source records attributed to A Caralps.

At least 37 records · Page 2Linked to original sources
PubMed1989

[Acute renal insufficiency induced at the hospital: prospective study and prevention].

To prevent hospital-induced acute renal failure (ARF), a prospective study was carried out, consisting of the recording of all cass of ARF in the hospital for a two month period (phase one). Their causes, evolution, prognostic indicators and the potentially preventable iatrogenic factors were recorded. On the basis of these data, several preventive measures were instituted (phase two) during 6 months; subsequently, during an additional 2 month period, the incidence of ARF was evaluated with the same methodology as in phase one. The number of evaluated individuals at risk (patients admitted to the hospital during the phases one and three) was 1470 and 1232, respectively. The number of recorded ARF episodes was 23 (1.6%) and 8 (0.65%) during the two periods, respectively. This reduction after the institution of preventive measures was statistically significant (p less than 0.04), with a complete disappearance of aminoglycosides as etiological factor, and a practical disappearance of multifactorial etiology, where risk diseases and drugs were also implicated. Iatrogenic factors were reduced from 75% (phase one) to 25% (phase three). The mortality rate of these patients was about 50% in both periods, and the only identified unfavorable prognostic factor was oliguria associated with ARF. It is concluded that the number of episodes of ARF, their preventable etiology and iatrogenic factors can be reduced by several prevention measures. It is advisable to implement these controls in a periodic fashion and to create surveillance committees of ARF in the hospital.

Adult↗
PubMed1989

Orthotopic renal transplant and results in 139 consecutive cases.

Although a commonly performed technique, heterotopic renal transplantation may be a cause of late graft failure owing to ureteral stenosis, urinary fistula and vesicoureteral reflux secondary to the immune response. The new retroperitoneal lumbar approach to the splenic vessels has allowed the orthotopic technique to be developed using the splenic artery or aorta, the renal vein and a pyelo-pyelic anastomosis. In this manner the renal graft is located in an anatomical position that is well protected, and with the recipient urinary tract the normal physiology is preserved with comparatively low complication and mortality rates. A third transplant attempt also is simplified. This method is the only alternative in some cases. Transplant ureter pathology symptoms are not observed. The results of 139 consecutive cases are presented.

Adult↗
PubMed1989

Hypertension and renal artery aneurysm: spontaneous cure.

An 18-year-old man is described with an aneurysm of the left renal artery diagnosed during study for hypertension. Medical treatment achieved control of the blood pressure. The patient voluntarily interrupted treatment 1 1/2 years after initial diagnosis but the blood pressure remained normal. Angiography at that time revealed almost complete thrombosis of the aneurysm and peripheral plasma renin activity returned to normal in contrast to the high figures registered initially (15 ng. per ml., normal values 0.51 to 2.64). The patient had normal blood pressure, received no medication and was on only a salt-free diet 1 year after this event.

Adolescent↗
PubMed1988

Apparent recurrence of hemolytic uremic syndrome in azathioprine-treated allograft recipients.

The present study describes 3 adult patients with hemolytic uremic syndrome (HUS) leading to chronic renal failure. Following renal transplantation, the 3 patients developed microangiopathic hemolytic anemia associated with acute rejection crises and graft failure. In 2 patients the renal histology of the transplanted kidney was consistent with HUS. It is concluded that, in adult patients, HUS may recur after renal transplantation and contribute to renal graft failure.

Adult↗
PubMed1988

Rhabdomyolysis, oedema and arterial hypertension: different syndromes related to topical use of 9-alpha-fluoroprednisolone.

Over a one year period we detected five cases of iatrogenic mineralocorticoidism secondary to topical application of creams containing 9-alpha-fluoro-prednisolone. Although the same product was involved in all cases, the clinical features differed and included two cases of myopathy and hypokalemic rhabdomyolysis, one of oedema and two of arterial hypertension. Discontinuation of treatment and administration of potassium supplements produced a rapid recovery and all patients remain well six months later.

Adolescent↗