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Biomedical subjects

A Campo

Publications and source records attributed to A Campo.

6 recordsLinked to original sources
PubMed1989

Severity of coronary artery disease among blacks with acute myocardial infarction.

A growing body of evidence suggests that survival after acute myocardial infarction (AMI) is considerably worse among blacks than whites. The severity of coronary artery disease (CAD), as measured by the number of diseased vessels and the degree of left ventricular dysfunction, is the major determinant of survival after AMI. To determine whether or not the severity of CAD could explain the poor prognosis in a cohort of blacks followed at this institution, cardiac catheterization was performed in a consecutive series of 51 patients less than 70 years of age. All patients were studied within 2 weeks after AMI. The mean age of the patients was 56 +/- 8 (mean +/- standard deviation) and 71% were men. A greater than or equal to 50 narrowing in 0, 1, 2 or 3 coronary arteries was noted in 5, 24, 40 and 31%, respectively. Left main stenosis was present in 3 patients (6%) and the mean left ventricular ejection fraction was 55%. In a subgroup of 20 patients echocardiographic estimates of left ventricular mass/height yielded a mean of 196 g/m, and left ventricular hypertrophy on echocardiogram was present in 74%. These data indicate that among blacks with AMI in this series CAD was only modestly more severe than expected and suggest that other factors most likely explain the high mortality in blacks after hospital discharge.

Black or African American↗
PubMed1989

Exercise ultrafast computed tomography for the detection of coronary artery disease.

Ultrafast computed tomography permits the assessment of global and regional left ventricular function during exercise. To evaluate the feasibility of using this new technique for the diagnosis of coronary artery disease, 27 patients undergoing cardiac catheterization for diagnosis of chest pain were evaluated. Fifteen patients had significant (greater than 50%) coronary artery stenosis by quantitative coronary angiography. One vessel disease was found in 12 patients and multivessel disease in 3. Fourteen (93%) of the 15 patients with significant coronary stenosis had a decrease in ultrafast computed tomographic ejection fraction during exercise from (mean +/- SD) 65 +/- 7% to 60 +/- 7% (p less than 0.001). The tomographic ejection fraction increased greater than 5% units during exercise in 10 (83%) of the 12 patients with normal coronary arteries. The mean tomographic ejection fraction in this group was 68 +/- 6% at rest and 75 +/- 6% at peak exercise (p less than 0.001). Regional wall motion was quantified by analyzing the segmental ejection fraction of 12 30 degree pie segments at each tomographic level of the left ventricle. A new regional wall motion abnormality developed during exercise in 12 (86%) of 14 patients with coronary artery disease; one patient was excluded because of a technical problem in data storage. Eleven (93%) of the 12 patients with normal coronary arteries had normal wall motion during exercise. In no patient with ischemic heart disease were both variables, ejection fraction response and regional wall motion, normal. Exercise ultrafast computed tomography appears to be a useful technique for the evaluation of coronary artery disease in patients with chest pain and predominant single vessel coronary artery disease.(ABSTRACT TRUNCATED AT 250 WORDS)

Adult↗
PubMed1988

Coronary artery disease in blacks of lower socioeconomic status: angiographic findings from the Cook County Hospital Heart Disease Registry.

During a 4-year period, 1,022 blacks underwent angiography at our institution for the presumptive diagnosis of coronary artery disease (CAD). Among the 454 men, at least one coronary stenosis was demonstrated in 288 cases (63%), while significant narrowing was found in 242 of 568 women (43%). Despite the frequent finding of normal coronary arteries, those patients with significant CAD had severe disease. Thus among men with CAD, left main stenosis was present in 7% and three-vessel narrowing was seen in 53%; among the women, 8% had left main stenosis and three-vessel disease was present in 52%. Two countervailing processes appear to be occurring, namely (1) identification of true coronary symptoms is difficult in this group of patients and (2) diagnosis of true cases occurs late in the course of the disease and the distribution of the number of vessels involved is skewed upwards. Increased echocardiographically determined left ventricular mass and hypertension were prevalent among all groups. These data suggest that the approach to the diagnosis of CAD in the black population is difficult and severe CAD occurs frequently.

Black People↗
PubMed1985

Impairment in auditory and visual function follows perinatal viral infection in the rat.

Acoustic startle reflexes are elicited by intense tone bursts but inhibited if weak bursts precede reflex elicitation. Rats were infected by intracerebral inoculation with lymphocytic choriomeningitis virus (LCMV) at birth. Compared to control animals, infected animals had higher elicitation and inhibition thresholds and showed recruitment at intense stimulus levels. Histopathology revealed both cochlear and retinal degeneration. Like some infectious agents in humans, perinatal exposure to LCMV in the rat yields a severe polysensory neuropathy.

Animals↗
PubMed1983

Runaway pacemaker.

We report a case of a runaway cardiac pacemaker in a hemodynamically unstable patient requiring surgical intervention for correction of the malfunction. The technique for gaining rapid access to the permanent pacemaker and disarming it, and for the utilization of a portable pacemaker generator to establish a normal heart rate is presented.

Aged↗