Diagnostic criteria (new and old) for the spondylarthropathies.
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Biomedical subjects
Publications and source records attributed to A Calin.
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Forty-seven % of 4,205 individuals living in a Puerto Rican community developed Shigella sonnei dysentery. Questionnaire and, where relevant, clinical evaluation of 1,970 patients and the remaining 2,235 unaffected residents disclosed no cases of Reiter's syndrome (RS). Among the possible explanations for failure to observe any cases is the important suggestion that S. sonnei is not arthritogenic.
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To define the epidemiology of post-dysenteric Reiter's syndrome (RS), 1,162 persons were questioned about compatible symptoms soon after 3 separate outbreaks of shigellosis. We diagnosed RS for 3 women of 204 persons ill during an outbreak of Shigella flexneri 1b, for 3 women of 206 ill during an outbreak of S. flexneri 2a, and for none of 85 ill during an outbreak of S. sonnei. We found no RS among 667 persons without diarrhea. Prospective controlled investigations in defined populations documented that RS follows S. flexneri 1b as well as 2a infections in about 1.5% of white adults with dysentery and indicated that women develop post-dysenteric RS as often as men.
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The association between chronic iridocyclitis and pauciarticular disease in childhood is well recognized. In view of this important subset of childhood arthritis, a comparable entity was searched for in adults. Twenty-three rheumatologists and 149 ophthalmologists were contacted in the San Francisco Bay area regarding the possible presence of this association in their catchment area of several million adult individuals. Replies were received from 15 and 41, respectively. Following detailed questionnaire and clinical evaluation of potential patients, only 2 such subjects were identified. These probably reflect a chance occurrence of 2 prevalent conditions. The apparent absence of the iridocyclitis/oligoarthritis subset in adults is in stark contrast to the situation in children.
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