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Biomedical subjects

A C Thurlow

Publications and source records attributed to A C Thurlow.

13 recordsLinked to original sources

Paradoxical air embolism during neurosurgery.

Four cases of air embolism which occurred during neurosurgical procedures in the sitting position are described, in whom the signs could be due to air in the coronary or cerebral arteries. It is suggested that, during venous air embolism in the sitting position, a significant number of patients are haemodynamically at risk from paradoxical air embolism, and that the serious consequences of venous air embolism in neurosurgery may be due to this.

Aged↗

Indoramin-induced hypotension. An evaluation during ear, nose and throat surgery.

Indoramin, a competitive alpha 1-adrenoceptor antagonist, was administered intravenously to 12 fit patients aged 20-49 years during general anaesthesia with either halothane or enflurane for ear, nose and throat surgery. A mean decrease of systolic blood pressure of 6 mmHg followed the initial dose of 0.1 mg/kg. Systolic blood pressures of 70-80 mmHg were achieved in nine patients using 0.29-4 mg/kg. The maximum effect of every dose was achieved within 3 minutes, with a probable duration of action of at least 30 minutes. Large changes of heart rate did not occur, though there was gradual slowing of the heart during each series of incremental administrations. Junctional rhythm, sometimes with bradycardia and hypotension, occurred in five patients (four in halothane group; one in enflurane group). Because of this, and the greater than ten-fold variation in decrease of blood pressure for a single weight-related dose, indoramin is not recommended for the reduction of blood pressure during halothane anaesthesia.

Adult↗

Metallized plastic sheeting in the prevention of hypothermia during neurosurgery.

Metallized plastic sheeting (m.p.s.) was found to be ineffective in the prevention of hypothermia in adult patients studied during neurosurgical operations. Twenty patients were wrapped in m.p.s. and 22 patients acted as controls. Mean oesophageal temperature in the m.p.s. group decreased from 36.2 degrees C to 35.4 degrees C after 3 h (control 36.5 degrees C to 35.4 degrees C). It was concluded that active warming systems are needed to maintain normothermia in patients undergoing neurosurgical operations.

Adult↗

Cardiac arrhythmias during outpatient dental anaesthesia: a comparison of controlled ventilation with and without halothane.

The frequency and nature of cardiac arrhythmia during two controlled ventilation techniques for endotracheal anaesthesia in dental outpatients have been compared. Both techniques used nitrous oxide and oxygen with alcuronium, but in one the additional agent was halothane and in the other it was fentanyl. The frequency of arrhythmia in both groups was 5%. No ventricular arrhythmia was seen but benign nodal rhythm was noted. It is suggested that the anti-arrhythmia effect of non-depolarizing muscle relaxants may prevent ventricular arrhythmia in patients receiving halothane.

Adolescent↗

Cardiac arrhythmia during outpatient dental anaesthesia: the advantages of a controlled ventilation technique.

Two techniques for endotracheal anaesthesia in dental outpatients have been compared: a spontaneous ventilation technique using nitrous oxide, oxygen and halothane, and a controlled ventilation technique using nitrous oxide and oxygen, with tubocurarine and fentanyl. The latter technique has several advantages: abolition of arrhythmias induced by surgery, more rapid and hence safer recovery, avoidance of suxamethonium, and avoidance of atmospheric contamination with and possible sensitization to halothane.

Adolescent↗

Dental anaesthesia.

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Anesthesia, Dental↗