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Biomedical subjects

A C Gribomont

Publications and source records attributed to A C Gribomont.

At least 19 recordsLinked to original sources

[Vitreo-retinal pediatric surgery: epidemiologic factors, etiology and prognosis].

The features of pediatric vitreoretinal surgery are different from those of the adult population. In order to identify those differences, our retrospective study, dealing with a consecutive series of 2230 patients who underwent vitreoretinal surgery, analyzes several parameters for the 43 young patients (under 19 years old) (2%). Two main results can be withdrawn from the study. First, trauma is a major cause of vitreoretinal surgery in children (30% of the cases), proportionally much more frequent than in adults. Second, patient's age is the only factor that significantly influences the surgical prognosis, with a success rate of 35% under the age of 10 years, and 73% above this age (p < 0.05). We conclude that pediatric vitreoretinal surgery has a more guarded prognosis compared to the one performed in the adult population.

Adolescent↗

[Primary intention to treat intraocular metallic foreign body using radical vitrectomy].

In order to compare the prognosis of eyes with a metallic intraocular foreign body withdrawn with a complete versus incomplete vitrectomy, our retrospective study analyzes the functional result and complications in a consecutive series of 13 eyes, depending on whether the vitrectomy included or not the removal of the posterior hyaloïd and the shaving of the vitreous base. Six eyes underwent one of these 2 surgical maneuvers. Three eyes underwent both of these 2 maneuvers and ended up with 10/10 visual acuity and no complications or reoperations. Among the 4 eyes that did not benefit from any of these 2 maneuvers, 3 required a vitrectomy revision because of a retinal detachment or a secondary hemorrhage. We conclude that a radical vitrectomy could improve the prognosis of eyes with an intraocular metallic foreign body.

Adult↗

[Preliminary results for treatment of rhegmatogenous retinal detachment and new material for episcleral buckle: silicone Korobelnik sponge].

In order to evaluate the efficacy and short-term tolerance of the Korobelnik sponge in the primary treatment of uncomplicated rhegmatogenous retinal detachments (RRD), a retrospective study dealing with the first 30 consecutive cases of RRD primarily operated on with the use of this Korobelnik sponge is undertaken. Primary anatomical success is obtained in 80% of the cases (24/30), with a mean postoperative follow-up of 3.1 months. Conjunctival inflammation or dehiscence are not observed. Two sponges have to be removed for unrelated reasons. The study shows that the Korobelnik sponge is a reliable and well-tolerated buckling material, at least in the short term.

Biocompatible Materials↗

[Posterior vitrectomy for dislocated nuclear fragments during phakoemulsification: incidence, risk factors and prognosis of postoperative retinal detachment].

INTRODUCTION: Dislocated nuclear fragments during phakoemulsification are a well-known complication. The treatment is often surgical, and serious complications, among which a retinal detachment may occur. The purpose of this study was to evaluate its incidence, risk factors, and prognosis. METHODS: This retrospective study included a consecutive series of 24 eyes undergoing posterior vitrectomy for dislocated nuclear fragments during phakoemulsification. The main outcome measures were the postoperative retinal detachment (incidence, risk factors, prognosis). RESULTS: Two retinal detachments occurred after vitrectomy, an incidence of 8%. In both cases, a significant inflammation of the anterior chamber and corneal decompensation were noted before vitrectomy. More than 50% of the nucleus was dislocated. Intraocular implant manipulation did not intervene in either case. Two tears occurred during vitrectomy in one case. The prognosis of the detachment, with proliferation, was poor in both cases. DISCUSSION: and conclusion: The high incidence of retinal detachment compares with that observed after phakoemulsification complicated by vitreous loss. Anterior segment deterioration, which compromises posterior segment visualization, and dislocation of more than 50% of the nucleus, that increases the risk of fragments falling on the retina during vitrectomy, may increase the occurrence of retinal detachment with a poor prognosis because of periretinal proliferation.

Adolescent↗

[Can vitrectomy without use of microscissors improve results of surgery for proliferative diabetic retinopathy?].

In order to test the hypothesis that in proliferative diabetic retinopathy surgery the vitrectomy without the use of microscissors could improve the results and decrease the rate of complications as well as the operating time, two groups are compared in a consecutive series of 24 eyes, operated on with or without scissors, and with a minimum follow-up of 6 months. The study shows that the vitrectomy without scissors offers a higher percentage of eyes with a postoperative visual acuity at least two lines better than the preoperative visual acuity. It shows also a trend for a shorter surgery, with fewer complications in case of vitrectomy without scissors.

Diabetic Retinopathy↗

[Surgery for idiopathic macular hole in stage III/IV: is long-acting gas tamponade indispensable?].

In order to test the hypothesis that in stage III/IV idiopathic macular hole surgery, a short-acting gas tamponade with 40% SF6 and postoperative positioning for 7 days is anatomically and functionally as successful as a long-acting gas tamponade with 14% C3F8 and a postoperative positioning for 14 days, 2 consecutive series of eyes operated on with the same technique, excepted for the gas tamponade used, are compared. The anatomical and functional success rates are not statistically different between both groups.

Adolescent↗

[Traumatic vitreous-retinal hemorrhage in infants].

After a short review of the non-traumatic, and rare, causes of vitreoretinal hemorrhages in infants, we analyze the 4 situations where a traumatic hemorrhage can be found: accidental head trauma, which has to be very severe and is then an unfrequent etiology, head trauma in child abuse or the so-called "shaken baby syndrome", which is the most frequent cause, and where we point out the key role of the ophthalmologist in the diagnosis and the prognostic evaluation, the perinatal trauma, which is a frequent, benign, and ephemeral cause, and finally, cardiopulmonary resuscitation, which is a controversial and unlikely cause.

Birth Injuries↗

[Surgery for idiopathic macular hole: use of internal limiting membrane peeling].

In order to evaluate the hypothesis that macular internal limiting membrane peeling is useful for closing stages III and IV, but not stages II idiopathic macular holes, anatomic and functional surgical results are compared in a consecutive series of 54 operated eyes including 3 groups: 17 eyes with a stage II macular hole and 18 eyes with a stage III-IV macular hole without additional internal limiting membrane peeling, and 19 eyes with stage III-IV macular hole with additional internal limiting membrane peeling.

Epiretinal Membrane↗

[Progressive deterioration of episcleral Miragel explants].

Miragel (TM) episcleral explants undergo deterioration with the passing years, so that their ablation becomes necessary in a growing number of cases because of progressive discomfort and/or diplopia. The present study deals with 13 eyes undergoing the removal of an episcleral Miragel explant between 10/1/96 and 10/15/98. The Miragel explant ablation, which is tedious because of the material alterations, gives excellent functional and cosmetic results. The risk of retinal detachment recurrence seems low.

Biocompatible Materials↗

[Weak and moderate myopia and the prognostic value of macular hole surgery].

The comparison of the anatomic and functional results of macular hole surgery, provided there is no associated retinal detachment, shows that preoperative myopia of at least 1 diopter, contrary to the preoperative stage of the hole according to the classification of Gass, is not a prognostic factor. This is suggested by the retrospective study of a consecutive series of 34 eyes operated on by the same surgeon.

Adolescent↗

Familial adenomatous polyposis associated with multiple adrenal adenomas in a patient with a rare 3' APC mutation.

Familial adenomatous polyposis (FAP) is characterised by hundreds of colorectal adenomas. Endocrine neoplasms have occasionally been reported, as have gastric polyps, which are usually hamartomatous in the fundus of the stomach and adenomatous in the antrum. A 57 year old man with colorectal, gastric, and periampullary adenomatous polyposis, in association with three bilateral adrenocortical adenomas, is presented. Mutation screening showed a 5960delA germline mutation in the adenomatous polyposis coli (APC) gene predicted to lead to a premature stop codon. This mutation was found in three of the four children of the patient. Western blot analysis of a lymphoblastoid cell line derived from the patient failed to detect any truncated APC polypeptide. This rare 3' mutation is responsible for an unusually complex and late onset phenotype of FAP.

Adenomatous Polyposis Coli↗

[The ophthalmological follow up of the premature infant must go on after the neonatal period].

Premature infants with very low birth weight (VLBW: < 1251 g) and/or gestational age lower than 32 weeks are at high risk of ocular abnormalities. Retinopathy is a well known complication of the neonatal period, but many abnormalities occur beyond the neonatal period, and must be carefully screened for years, mainly: cicatricial retinopathy, myopia, strabismus, glaucoma, retinal detachment and various functional visual impairments. Guidelines for the postneonatal screening of these abnormalities are given.

Continuity of Patient Care↗

[Precocious exudative retinal detachment after surgery of the macular hole].

The retrospective study of our patients operated on for an idiopathic macular hole shows 2 cases of presumed exudative retinal detachment appearing 24 to 36 hours after surgery. This complication, to our knowledge, has never been reported. We describe these 2 cases and discuss on one hand, the arguments for an exudative etiology of the retinal detachment, and on the other hand, the possible causes of this unusual complication.

Aged↗

[Role of vitrectomy and intra-vitreous injections in the treatment of traumtic and iatrogenic endophthalmitis].

The survey of recent literature emphasises the usefulness of primary vitrectomy in the treatment of the most serious endophthalmitis. As soon as vitreous and aqueous humor samples have been obtained for bacteriologic analysis, intravitreal injection of a combination of antibiotics able to cover the most common causative germs is established as the standard of care. The beneficial effect of intravitreally-injected corticosteroids is still controversial.

Adrenal Cortex Hormones↗

[Idiopathic epimacular membrane and vitreo-macular traction syndrome: vitrectomy functional results].

The retrospective study of 26 consecutive cases of idiopathic epimacular membrane and vitreomacular traction syndrome treated by vitrectomy with a mean follow-up of 19 months showed very good functional results. The visual acuity at the last visit improved by 2 lines or more when compared with the preoperative visual acuity in 77% of pseudophakic eyes and eyes with clear lens. The metamorphopsia disappeared or significantly diminished in half the cases. The main postoperative complication was the appearance or progression of nuclear sclerosis, which could mask the good functional results of vitrectomy.

Adult↗

[Metallic intraocular foreign body extraction by primary vitrectomy and microforceps].

This retrospective study deals with 17 consecutive cases of metallic intraocular foreign body extraction with primary vitrectomy and microforceps. The methods of surgical treatment in this setting are controversial. We discuss these methods, and show that the surgical principles applied in this series have allowed us to obtain functional results which compare favorably with those previously published, and a very low level of retinal complications with respect to other studies.

Adult↗

[Surgical treatment of idiopathic macular hole: what is new one year later].

We report the results of 23 idiopathic macular hole surgeries on 23 patients consecutively operated on. There are 20 stage III and 3 stage II holes, according to the classification of Gass. Anatomical success, defined as a macular hole with a 360 degrees flat edge, or as a macular hole which is no more visible, is obtained in 13 cases; functional success, defined as a visual acuity improvement of 2 lines or more at the last visit, is obtained in 11 cases. Postoperative rhegmatogenous retinal detachment is noted in 2 cases. With such results, our conclusions are less optimistic as in 1994. If macular hole surgery is very efficient in some patients, larger studies are still needed in order to better define the most successful surgical indications and technique.

Aged↗