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Biomedical subjects

A C Gonzalez

Publications and source records attributed to A C Gonzalez.

24 records · Page 2Linked to original sources

Imaging of experimental myocardial contusion: observations and pathologic correlations.

Myocardial contusions of variable severity were experimentally produced by an air-driven piston or serrated clamp in 29 dogs. Two 99mTc-labeled bone-seeking agents (99mTc pyrophosphate and 99mTc tetracycline) were used with cardiac scintigraphy to determine the sensitivity of these agents in detecting different degrees of myocardial damage. Results showed that 99mTc tetracycline was not a suitable scanning agent. 99mTc pyrophosphate produced positive scans in cases of complete (or nearly complete) transmural myocardial necrosis. Positive cardiac scans in clinical myocardial contusion may indicate the severity of the lesions and have prognostic significance.

Animals↗

Acute pancreatic pseudocysts: incidence and implications.

Of 92 patients with moderately severe acute pancreatitis initially studied within three weeks of onset by ultrasonic tomography, 52 developed an acute fluid collection in the lesser sac. Documentation of the ultrasound prediction of pseudocyst was achieved by surgery or autopsy in 26 cases. Spontaneous resolution of the acute pseudocyst was demonstrated by serial ultrasonography and radiogrphy in another 10 patients. Exploration exposed 3 false positive predictions of pseudocyst. Eleven other patients with a cystic configuration either refused surgery or were lost to followup. Acute pseudocyst formation is a relatively common phenomenon in the early phases of moderately severe pancreatitis. While spontaneous resolution of acute pseudocysts is frequent, in approximately 50% of cases acute pseudocysts progress to chronic pseudocysts. A distinction between acute and chronic pseudocyst is necessary since specific surgical management depends upon the phase of pseudocyst development. Unless regional sepsis supervens, acute pseudocyts of less than three weeks' duration may be followed by serial ultrasonography in the hope of spontaneous resolution. When a pseudocyst has achieved chronic status, spontaneous resolution is rare. Persistent conservative management under these conditions invites the excessive mortality and morbidity of spontaneous rupture.

Acute Disease↗

Pseudocyst formation in acute pancreatitis: ultrasonographic evaluation of 99 cases.

A total of 99 patients admitted with a diagnosis of acute pancreatitis were studied by abdominal A- and B-mode ultrasonography in an effort to detect pseudocyst formation. Positive ultrasonic scans were noted in 52 cases. In three patients with positive sonography, surgical exploration did not demonstrate pseudocysts, giving a false positive rate of 8.3%. Of the negative studies four were proven incorrect at surgery or autopsy , yielding a false negative rate of 8.5%. Approximately one-fifth with cystic lesions underwent spontaneous resolution. Three additional patients with pseudocysts had spontaneous cyst-enteric fistulization demonstrated by radiography. The sensitivity and accuracy of pancreatic ultrasound demonstrated by this study established ultrasonography as the procedure of choice in detecting pseudocyst formation in patients with acute pancreatitis.

Adolescent↗