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Biomedical subjects

A C Gibson

Publications and source records attributed to A C Gibson.

8 recordsLinked to original sources
PubMed1988

Dietitians improve diabetic control in general practice.

Fifteen diabetic patients with problems related to poor dietary adherence, ie, obesity, hyperlipoproteinaemia, high levels of glycosylated haemoglobin (HbA1C), were studied before and after the introduction of a dietary clinic to a general practice: none of these patients attend hospital for care of their diabetes. There was high patient acceptance of the offer of local dietary advice. Definite improvement in weight and hypertriglyceridaemia was shown with some evidence also of reduced HbA1C. Serum cholesterol levels were unchanged.

Body Weight↗
PubMed1978

Sodium valproate and tardive dyskinesia.

Twenty-five schizophrenic patients with tardive dyskinesia was given 600 mgs sodium valproate daily with their neuroleptic medication. After one month there was no change in their signs, as judged by a panel of nine viewing films of them taken before and at the end of this treatment.

Adult↗
PubMed1978

Depot injections and tardive dyskinesia.

A prospective study was undertaken on 374 out-patients receiving depot fluphenazine or depot flupenthixol to determine the incidence of tardive dyskinesia. In three years the percentage showing the bucco-linguo-masticatory syndrome rose from 8 per cent to 22 per cent, though patients had received various neuroleptics for a mean of 13 years previously. Fluphenazine and flupenthixol were equally involved though 75 per cent of affected patients had the condition in mild degree. Six additional cases of generalized chorea were all receiving flupenthixol. Reduction of dose or the substitution of pimozide produced marked improvement, but results suggest that it is unlikely that this will be permanent. Substitution of depot fluspirilene also produced favourable results. Careful monitoring, minimal neuroleptic dosage, and periods of neuroleptic abstinence are recommended.

Chorea↗