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Biomedical subjects

A C Friedman

Publications and source records attributed to A C Friedman.

At least 91 records · Page 5Linked to original sources

Adult acquired antral web.

Gastric antral webs in adults have been considered to be either congenital or acquired lesions. We present the first radiographically documented progression from a normal antrum to the development of an antral ulcer followed by healing with web formation. In a single study we feel that irregularity of the web and deformity or eccentricity of the antrum favor an acquired rather than a congenital web. Obtaining prior radiographs as well as follow-up examinations may be the only way to prove association with peptic disease.

Cicatrix↗

Primary malignant renal tumors in the second decade of life: Wilms tumor versus renal cell carcinoma.

Primary renal malignancies occur least frequently in the second decade of life. Of the 4,798 cases of renal cell carcinoma and Wilms tumor referred to the Armed Forces Institute of Pathology 53 renal cell carcinomas and 56 Wilms tumors occurred in the 10 to 20-year age group. Pathologically, both tumors in this age range are similar to those occurring at a more typical age, and histologic differentiation between renal cell carcinoma and Wilms tumor is seldom a problem. While radiographic evaluation is useful to characterize the neoplasm, evaluate the contralateral kidney and detect the presence of tumor extension, current imaging techniques cannot confidently distinguish these 2 tumors.

Adenocarcinoma↗

Anomalies of the left renal vein: analysis of 433 CT scans.

The incidence of circumaortic left renal vein (4.4%) and single retroaortic left renal vein (1.8%) was evaluated in 433 abdominal computed tomography (CT) studies. Computed tomography was felt to be adequate for demonstrating anomalies in a majority of cases. Important preoperative evaluation can be provided by routine CT, obviating more invasive procedures in some instances. Differentiation of these anomalies from retroperitoneal pathology can be made by the radiologist.

Contrast Media↗

Renal lymphoma: radiologic-pathologic correlation of 21 cases.

The radiologic findings in 21 cases of renal lymphoma were correlated with the gross and microscopic pathologic findings. The gross morphology and consequent radiographic images depend upon the mechanism of renal involvement (hematogenous or direct extension); the pattern of intrarenal growth (interstitial or expansile); the size, number, and distribution of lesions; and the presence of extension beyond the kidney. Initially, the lymphoma grows between nephrons that may continue to function and, because this interstitial proliferation preserves gross morphology, radiographic detection may be difficult. With continued growth, the scaffolding along which the tumor infiltrates is destroyed, growth becomes expansile, and the lymphomatous mass resembles other renal neoplasms that enlarge by appositional growth. Continued growth and coalescence of small foci result in progressive parenchymal replacement and, rarely, in destruction of the entire kidney. Perinephric extension with subsequent vascular and ureteral encasement is common.

Adolescent↗

CT of benign cystic teratomas.

The computed tomographic (CT) findings in nine benign cystic teratomas are presented and compared with radiographic, sonographic, and pathologic data. CT rendered a specific diagnosis in six cases and was highly suggestive in two, with results superior to other imaging methods. In each instance, CT was successful in predicting or excluding invasion of adjacent structures, but was not reliable in predicting or excluding adherence to them. Specific CT characteristics of benign cystic teratomas are predominantly fatty mass with a denser dependent element and globular calcification, bone, or teeth in a solid protuberance into the cyst cavity. Suggestive patterns include fatty mass with rim calcification and water density mass with globular calcification and solid tissue elements. Illustrated for the first time are the CT appearances of the different calcifications seen in benign cystic teratomas.

Abdominal Neoplasms↗

Paget disease of the hand: radiographic spectrum.

Paget disease uncommonly affects the hand. When it does, radiographic findings are same as when the disease occurs elsewhere. Eleven new cases that demonstrate four predominant radiographic patterns are described: homogeneous sclerosis, trabecular coarsening, cortical thickening, and lysis. The homogeneous sclerosis pattern was associated with monostotic hand disease. One patient developed bilateral phalangeal osteosarcomas. In every case, the disease process extended to the subarticular region and the affected bone was enlarged. With one exception, both ends of the bone were involved.

Adult↗