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Biomedical subjects

A C Drogendijk

Publications and source records attributed to A C Drogendijk.

At least 73 records · Page 4Linked to original sources

Ultrasonic diagnosis of placenta membranacea.

In this paper the first known case is presented in which an antepartum diagnosis of placenta membranacea was made by ultrasound. A multiparous woman is presented with intermittent painless vaginal bleeding in the second trimester of pregnancy. Ultrasonic examination at 20 weeks' gestation revealed a gestational sac almost completely covered with placental tissue. At 26 weeks the patient delivered a dead, growth retarded and an almost complete placenta membranacea.

Adult↗

A combined ultrasonic and biochemical study of fetal renal function in the term fetus.

The fetal glomerular filtration rate of plasma (GFR) and the percentage of fetal tubular reabsorption of water were measured by means of combined ultrasonic and biochemical methods in 20 normal and 10 complicated pregnancies. The duration of pregnancy varied from 35 to 42 wk. In normal pregnancy GFR of plasma varied from 2.0 to 7.1 ml/min (mean = 4.1) and tubular reabsorption of water ranged from 84.1 to 93.0% (mean = 89.8). There was no relationship with gestational age. In the group of complicated pregnancies - apart from one anencephalic case - no apparent difference in GFR and percentage tubular reabsorption between the group of normal (greater than or equal to 10th percentile) and reduced fetal birth weight (less than 10th percentile) was observed.

Diuresis↗

Evaluation of fetal heart rate in relation to the intrauterine 20 mm Hg level.

The purpose of the author's study was to investigate whether any changes in fetal heart rate (FHR) and in fetal acid-base status could be observed when the intrauterine pressure rises above 20 mm Hg. 16 primigravidae were studied. In 11 out of 16 patients labor was induced by amniotomy, in 9 cases oxytocin was given, and in 12 patients pethidine and promethazine (Phenergan) was administered. Two new parameters were introduced into the study of the collected material: the peak variation in FHR (bpm) i.e. the difference between the highest and lowest FHR over a given period of time; the contraction energy, i.e. the product of duration and intensity of intrauterine contractions as measured from the 20 mm Hg level. In 15 out of 16 women the mean peak variation in FHR was highest during a uterine contraction (greater than 20 mm Hg). After a uterine contraction (less than 20 mm Hg) the mean peak variation did not immediately return to control values. It is suggested that in the 16 patients studied, the increase in FHR peak variation during uterine contraction is basically caused by a slight transient fetal hypoxia, exaggerated during the expulsion period of labor by cord entanglement.

Female↗