Chronic fatigue syndrome.
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Biomedical subjects
Publications and source records attributed to A C Chester.
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Symptoms of chronic sinusitis include facial pain, rhinorrhea and malaise. Infection, allergies and vasomotor rhinitis/ sinusitis are the usual causes. Physical examination, laboratory results and routine radiologic findings are often minimal. Computed tomographic scanning, however, may show pathology that is not apparent on standard radiographs. Nonpharmacologic treatments should be considered first. Increased exercise and nasal steam inhalation may help. Dietary restrictions or a change in environment are occasionally quite beneficial. Intranasal corticosteroids and brief courses of local decongestants are frequently appropriate. Systemic therapy, including decongestants, anti-inflammatory agents, antibiotics and, occasionally, antihistamines, offers treatment directed at the causes of chronic sinusitis. When aggressive medical treatment is unsuccessful, nasal surgery, particularly endoscopic surgery, directed at abnormalities of the ostiomeatal unit, may offer significant benefit for selected patients.
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Sick building syndrome (SBS) is usually characterized by upper respiratory complaints, headache, and mild fatigue. Chronic fatigue syndrome (CFS) is an illness with defined criteria including extreme fatigue, sore throat, headache, and neurological symptoms. We investigated three apparent outbreaks of SBS and observed another more serious illness (or illnesses), characterized predominantly by severe fatigue, that was noted by 9 (90%) of the 10 teachers who frequently used a single conference room at a high school in Truckee, California; 5 (23%) of the 22 responding teachers in the J wing of a high school in Elk Grove, California; and 9 (10%) of the 93 responding workers from an office building in Washington, D.C. In those individuals with severe fatigue, symptoms of mucous membrane irritation that are characteristic of SBS were noted but also noted were neurological complaints not typical of SBS but quite characteristic of CFS. We conclude that CFS is often associated with SBS.
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Two cases of severe unexplained fatigue with mid-facial pain and rhinitis are presented. Sinus computerized tomography (CT) findings were minor, but both responded to functional endoscopic nasal surgery with resolution (Case 1) or near resolution (Case 2) of chronic fatigue. Possible mechanisms linking nasal disease and chronic fatigue include reflex etiology and sleep disturbance associated with abnormal nasal airflow. Often not considered by the primary care physician in differential diagnosis of fatigue, chronic sinusitis should be explored as a cause in unexplained cases.
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In an effort to better describe the incidence and characteristics of chronic giardiasis in an urban private practice outpatient setting, we reviewed our experience of 65 cases. In the entire group, the mean duration of symptoms was 1.9 years. A history of foreign travel was described by 45%. No association with homosexuality was noted. Chronic giardiasis, defined as that population symptomatic for six months or longer, constituted 58% of the entire group (38 cases). For these patients the mean duration of symptoms was 3.3 years. When compared to acute giardiasis, an increased frequency of constipation and upper gastrointestinal complaints was noted in the chronic population. Symptomatic cure was obtained in 71% of chronic cases and 93% of acute. Palliative results were noted in 18% of chronic cases and 4% of acute. We conclude that giardiasis is frequently a chronic disease in our population with symptoms lasting years. The incidence is similar in both sexes and a history of foreign travel is often absent. A disproportionate incidence in male homosexuals was not noted in our study.
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