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Biomedical subjects

A C Buck

Publications and source records attributed to A C Buck.

48 records · Page 3Linked to original sources
PubMed1970

Trimethoprim as an additional selective agent in media for the isolation of N. gonorrhoeae.

The incorporation of trimethoprim into existing selective media using either saponin-lysed blood agar or chocolate agar as the base is suggested for the routine isolation of the gonococcus. The principal advantage over other selective media is the inhibition of Proteus mirabilis and other commensal organisms as a consequence of which multiple swabs can be plated out onto a single selective plate irrespective of source, while the recovery rate of the gonococcus from these specimens is increased. The relative merits of both basic media are briefly discussed.

Agar↗
PubMed1968

Absorption of antibiotics during peritoneal dialysis in patients with renal failure.

Cloxacillin, ampicillin, cephaloridine, kanamycin, and polymyxin B were administered singly in the dialysis fluid of patients having peritoneal dialysis for chronic renal failure. Therapeutic blood levels could be attained with all the drugs by the end of 12 hours of dialysis, using a concentration in the dialysis fluid which did not produce any local toxic symptoms. Absorption rates across the peritoneum were higher for cephaloridine, ampicillin, and cloxacillin than for kanamycin and polymyxin B. The serum half-lives after termination of dialysis were in excess of 11 hours, except that for cloxacillin which had a half life of about 2.5 hours.

Absorption↗