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Biomedical subjects

A Bourlond

Publications and source records attributed to A Bourlond.

At least 55 records · Page 3Linked to original sources

[Angiosarcoma of the breast].

A painless ecchymotic plaque developed progressively on the right breast of a 16 years old girl. Failure of the first biopsies to bring up specific lesions and episodes of regression delayed the diagnosis until a very deep biopsy and a CT-scan investigation revealed a diffuse and malignant vascular process. A simple mastectomy did not prevent recurrence and metastasing 3 months later. The clinical aspects of breast angiosarcoma, the shortcomings of investigative procedures and the recommended therapeutics are reviewed.

Adolescent↗

Alternariasis: ultrastructure of skin granuloma.

An ultrastructural investigation of dermal altenariasis has complemented previous studies. Alternaria tenuis was seen to be profusely present within the cytoplasm of multinucleate giant cells. Healthy elements were characterized by a thick, electron-lucent wall, ovoid osmiophilic inclusions and a poorly defined nucleus. Homogenous liquefaction and granular degeneration represented various types and steps of degradation; the wall subsisted for a while before collapsing and breaking into pieces. Penetration of the giant cell's cytoplasm within hollow tubes was observed.

Adult↗

[Idiopathic calcinosis of the scrotum (author's transl)].

Clinical and histological features of idiopathic calcinosis of the scrotum are presented; calcium deposits are never associated with epithelial or connective tissue alterations. Identical lesions may arise in the skin at large; discrepancies and similitudes with cutaneous calculi are underlined.

Adult↗

[Review: beta-blocking agents in dermatology (author's transl)].

The authors present a survey of the side effects of beta-blocking agents. Practolol has been linked with a lupus syndrome characterized by biological abnormalities and eventually clinical signs; later on, other beta-blocking agents have been able to induce such manifestations. Thus, all beta-blocking agents proved hazardous and they must be prescribed with extreme caution in patients with immunological imbalance. Furthermore, pruritus and lichenoid or psoriasiform dermatitis have been documented. This must be kept in mind in the presence of any unspecific rash in elderly patients.

Adrenergic beta-Antagonists↗

[Epidermotropic reticulosis of the Woringer-Kolopp type (author's transl)].

A 46-year-old female, otherwise healthy, developed erythematous, pseudotumoral nodules, mainly on the hands; biopsies led to the diagnosis of Woringer-Kolopp disease. Anti-anergic chemotherapy with levamisole proved hazardous but, possibly, beneficial. Classification into benign localized, fatal generalized and intermediate disease is briefly commented upon. Differential diagnosis and tumor origin are discussed; while the Merkel cell hypothesis has been recently advanced strong analogies and slight discrepancies with mycosis fungoides advocate the T cell lymphoma theory.

Diagnosis, Differential↗

Cutaneous innervation.

This is a review of historical facets of research in cutaneous neurohistology. The silver stains, used for some 150 years, led to the discovery of the neurone theory and to contemporary comparative studies. The cholinesterase methods, used since 1950, are the most convenient for general studies of nerves. The fluorescence technique of Falck (1962) is valuable for the study of adrenergic fibers. The electron microscope techniques used since 1950 have allowed the comprehensive description of myelinated and unmyelinated nerve fibers and of corpuscles. The most important unsettled questions pertain to the physiology of cutaneous nerves and precise definitions of cutaneous sensibility.

Animals↗

[Eczema herpeticum. Clinical observation and ultrastructural study].

A child afflicted with atopic dermatitis developed a Kaposi-Juliusberg's syndrome. Virological and ultrastructural investigations proved a widespread herpes virus infection. Maturation of the virus within the nuclei of epidermal cells and its release into the cytoplasm and the intercellular space have been studied at the ultrastructural level and some peculiar data brought up.

Dermatitis Herpetiformis↗