Search PubMed⌕ Search

Biomedical subjects

A Borgeat

Publications and source records attributed to A Borgeat.

At least 127 records · Page 7Linked to original sources
PubMed1988

Hemofiltration clearance of flecainide in a patient with acute renal failure.

Flecainide, a new antiarrhythmic drug, has been shown not no be removed to a significant extent by hemodialysis or peritoneal dialysis, in spite of a high renal clearance. Its systemic and hemofiltrate clearances, measured in a patient under continuous hemofiltration, were 402 and 19.7 ml/min respectively. The clearance ratio of less than 5% makes the contribution of hemofiltration to the elimination of flecainide clinically negligible.

Acute Kidney Injury↗
PubMed1988

Grand mal seizure after extradural morphine analgesia.

Following an elective Caesarean section under extradural anaesthesia, a 30-yr-old known epileptic woman (gravida 4, para 3) developed a tonic-clonic seizure, 6 h after the administration of morphine 3 mg into the extradural space. Possible aetiological factors are discussed.

Cesarean Section↗
PubMed1987

Accelerated idioventricular rhythm during flexible fiberoptic bronchoscopy.

We report the case of a patient who developed severe hypoxemia and an unusual arrhythmia, accelerated idioventricular rhythm, during flexible fiberoptic bronchoscopy. Coronary artery disease was subsequently suspected despite an unremarkable history and physical examination, and confirmed by a thallium 201 imaging. The appearance of accelerated idioventricular rhythm during fiberoptic bronchoscopy should raise the possibility of underlying coronary artery disease.

Aged↗
PubMed1986

[Syncope in a 16-year-old young man during a football match].

A case is reported of a previously healthy 16-year-old boy who developed a rapid atrial fibrillation following a minor thoracic impact. This tachyarrhythmia resistant to several drugs responded immediately to administration of flecainide. The restoration of sinus rhythm led to diagnosis of type A Wolff-Parkinson-White syndrome.

Adolescent↗
PubMed1986

Flecainide versus quinidine for conversion of atrial fibrillation to sinus rhythm.

The effectiveness and safety of flecainide and quinidine for conversion of atrial fibrillation (AF) to sinus rhythm were compared. Sixty consecutive patients were treated with either flecainide (up to 2 mg/kg intravenously and then orally) or quinidine (up to 1.2 g orally). There was no statistical difference in age, left atrial size, duration of the arrhythmia and underlying cardiac diseases between the 2 groups. The overall conversion rate to sinus rhythm was 63% (38 patients): AF was converted in 18 patients (60%) treated with quinidine and 20 (67%) with flecainide. If AF lasted less than 10 days, the conversion rate was 86% in the flecainide group and 80% in the quinidine group (difference not significant). When AF lasted more than 10 days the rate was 22% in the flecainide group and 40% in the quinidine group. Adverse effects were more frequent in the quinidine group (27%) (gastrointestinal disturbances) than in the flecainide group (7%) (conduction disturbances), but they were less severe in the quinidine group. Thus, flecainide given intravenously appeared to be as effective as quinidine given orally for conversion of AF of recent onset (within 10 days). However, quinidine should probably remain the preferred drug for conversion of AF of long duration (more than 10 days) to sinus rhythm. Adverse effects occurred less often with flecainide therapy, but they were more severe.

Adolescent↗
PubMed1986

Peripheral neuropathy associated with high-dose Ara-C therapy.

Central nervous system toxicity associated with high-dose cytosine arabinoside (Ara-C) therapy (HD Ara-C) is well known. The authors report the case of a severe isolated peripheral polyneuropathy due to HD Ara-C. Electrophysiologic changes and histologic observations were consistent with axonal degeneration and scattered destruction of myelin sheaths. This observation emphasizes the need for careful complete neurologic evaluation for patients receiving HD Ara-C treatment.

Adult↗
PubMed1986

[Variant angina pectoris: unusual clinical picture and course].

A case of variant angina with angiographically "normal" coronary arteries is reported. The clinical picture had been dominated by chronic stable angina for six years, and this symptomatology was complicated by pain at rest and also during the night. Two years later the patient had a myocardial infarction.

Angina Pectoris, Variant↗
PubMed1983

[Acute kidney failure due to drugs or toxic substances].

The main causes and mechanisms of acute renal failure due to drugs and other chemicals are briefly reviewed. In clinical settings, aminoglycoside antibiotics appear to be the drugs most commonly involved in acute toxic kidney diseases. Beta-lactam antibiotics have been most commonly associated with acute tubulo-interstitial lesions, which are thought to be due to immunological mechanisms. The important role of risk factors in toxic nephropathies is stressed.

Acute Kidney Injury↗
PubMedDate not supplied

The effect of nalbuphine and droperidol on spontaneous movements during induction of anesthesia with propofol in children.

STUDY OBJECTIVE: To investigate the effects of droperidol and nalbuphine on spontaneous movements during induction of anesthesia with propofol in children. DESIGN: Randomized, double-blind study. SETTING: Inpatient ear, nose, and throat (ENT) surgical clinic at the University Hospital of Geneva. PATIENTS: Forty-five children, ages 4 to 12 years, undergoing routine elective ENT surgery. INTERVENTIONS: Children were randomly assigned to receive either nalbuphine 0.1 mg/kg, droperidol 0.025 mg/kg, or isotonic saline 3 minutes before anesthesia induction. Induction was performed with a loading dose of propofol 3 mg/kg. MEASUREMENTS AND MAIN RESULTS: Spontaneous movements were observed in 33%, 87%, and 100% of patients in the nalbuphine, droperidol, and control groups, respectively. The movements were dystonic and choreiform in nature and were similar in all three groups. The frequency of spontaneous movements was significantly reduced (p < 0.05) in the nalbuphine group as compared with the droperidol and control groups. CONCLUSIONS: Nalbuphine, but not droperidol, decreases the frequency of spontaneous movements induced by propofol during induction of anesthesia in children; neither quality of induction and recovery nor interval between the end of propofol administration and tracheal extubation were modified by nalbuphine as compared with the control group.

Adjuvants, Anesthesia↗