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Biomedical subjects

A Bollinger

Publications and source records attributed to A Bollinger.

At least 127 records · Page 7Linked to original sources
PubMed1987

[Differential indications for surgical and conservative internal medicine procedures in the treatment of acute ischemia of the leg].

Re-opening of the main arterial pathway is the most efficient method for treatment of arterial occlusive disease in stage III and IV. In addition to surgical thromb-embolectomy catheter procedures such as percutaneous transluminal angioplasty, catheter lysis and catheter extraction of fresh clots may give satisfactory results. The following methods are indicated in acute cases: catheter procedures for occlusions of the popliteal trifurcation and profound femoral artery, segmental occlusions of the superficial femoral artery, femoro-popliteal occlusions with impaired run-off, recurrent occlusions after desobliteration with both surgical methods, occlusions of lower arm arteries; surgical thrombectomy for occlusions of the aortic bifurcation, the iliac arteries, the femoral bifurcation, for femoro-popliteal aneurysms and for occlusions of the subclavian and axillary artery. Both procedures do not exclude each other and may be combined according to the relevant indications.

Angioplasty, Balloon↗
PubMed1987

A versatile incident illuminator for intravital microscopy.

A simple incident illuminator (epiilluminator) for intravital microscopy using a mirror with 50% reflectance and 50% transmittance, placed at 45 degrees to the optical axis of the microscope, in combination with a polarizer and analyzer is described. Such a system can easily be mounted in a Ploemopak incident illuminator as used for fluorescence microscopy. Images of the red blood cells contained in the microvessels appear as dark on a light background. With the use of the system, microscopic images of good quality could be obtained from human skin capillaries, and skin, pial and intestinal microvessels in rats. In muscle, however, only the superficial capillaries could be adequately visualized.

Capillaries↗
PubMed1987

Infrared fluorescence videomicroscopy of skin capillaries with indocyanine green.

A new intravital capillary microscopic technique is described using intravenous indocyanine green (Cardiogreen) in combination with a special filter set, an infrared sensitive microchip videocamera and a television-recording system. The technique was used to measure arterial and venous limb capillary diameters in 29 nailfold capillaries from 11 healthy volunteers. The results were compared with measurements of erythrocyte column diameters from the same capillaries. Erythrocyte column diameters were 68% of arterial and venous limb capillary diameters determined with indocyanine green fluorescence videomicroscopy. (Arterial limb: 12.1 +/- 3.0 micron versus 17.8 +/- 3.9 micron; Venous limb: 13.7 +/- 4.1 micron versus 20.1 +/- 4.4 micron) (p less than 0.01). As indocyanine green is nearly 100% protein bound, these differences of 5-7 micron presumably correspond to the plasmatic zone interposed between the erythrocytes and the capillary wall. Other potential uses for the technique in clinical investigations of microcirculatory disturbances are briefly discussed.

Adult↗
PubMed1986

[Diagnosis and clinical course of periarteritis nodosa].

The clinical symptoms, diagnostic procedure and course under treatment in 10 patients with polyarteritis nodosa are studied retrospectively. Clinically, 3 patients showed peripheral arterial occlusive disease in the lower extremities. 3 patients had evidence of preceding acute type B hepatitis. The diagnosis was confirmed by biopsy in 7 cases, by selective arteriography of the kidneys showing multiple small aneurysms in one case; in 2 patients the diagnosis was based upon the clinical findings only. Complete remission was achieved in 7 of 10 treated patients, in 5 patients with corticosteroids alone and in 2 patients with a combination of corticosteroids and cytotoxic agents. 4 patients died, one of them from vasculitis and 3 from other causes. 5-year survival for all patients was 52%. The diagnostic value of arteriography, the clinical picture of polyarteritis nodosa with peripheral arterial occlusive disease, and the association between hepatitis B infection and polyarteritis nodosa are discussed.

Adult↗
PubMed1986

[Regional hypoplasia of dermal lymphatic vessels--a new variant of congenital lymphedema].

The value of new investigative methods of the most peripheral lymphatics of the skin (fluorescence microlymphography, indirect lymphography) is demonstrated by the case report of an 18 year-old girl. Regional hypoplasia of dermal lymphatics was detected in the lymphoedematous proximal and middle phalanges of the fingers while the initial lymphatics of the normal-appearing distal phalanges showed no obvious change. The subcutaneous lymph-collectors were ectatic and increased in the oedematous parts as well as in the normal-looking ends of the fingers. Hence, this is a new variant of lymphoedema, which is not caused by hypoplasia of lymph-collectors, but by a regional lack of initial lymphatics of the skin.

Adolescent↗
PubMed1986

[Mesenterial anemia as a cause of jogging anemia?].

Anemia in runners is common but its origin is unknown. The present study reports on frequency and origin of gastrointestinal blood loss in cross-country skiers and runners. 41 participants in the Engadin Ski Marathon were checked by questionnaire and occult blood test. 8 (19%) had diarrhea or abdominal pain during or immediately after skiing and 3 (7%) had hemoccult-positive stools. In addition, the blood flow of the superior mesenteric artery was measured by duplex scanning in two trained runners after standardized exercise. While the mesenteric blood flow in the asymptomatic runner changed only insignificantly there was an impressive decrease in the second runner, who had been treated for anemia, down to 20% and 40% (30 and 90 min respectively) after exercise. It is concluded that the occurrence of gastrointestinal blood loss in cross-country skiing, and the significant decrease in mesenteric blood flow in a symptomatic runner, indicate a close and possible causal relationship between mesenteric ischemia and "jogging anemia".

Adult↗
PubMed1986

Juvenile arteritis of extracranial arteries with hypereosinophilia.

The case history of a 23-year-old man presenting with a progressive tender swelling in both temporal regions is described. Eosinophilia varied between 28% and 48% and IgE was markedly increased (1,380 U/l). Arteriography revealed tortuous, enlarged temporal and occipital arteries intersected by stenoses. The pathology diagnosis was chronic necrotizing panarteritis of the temporal artery with pseudoaneurysms, fibrinoid necroses, scar tissue, occasional giant cells, and abundant hypereosinophilia.

Adult↗
PubMed1986

[Video-microscopic studies of telangiectases in Osler's disease and scleroderma].

4 patients with hereditary hemorrhagic telangiectasia (Osler's disease) have been studied by clinical means and by fluorescence videomicroscopy. The capillaroscopic image was characterized by convolutes of giant capillaries (diameter up to 150 micron, normal value up to 15 micron) between capillaries of normal shape and size. After intravenous injection of Na-fluorescein the enlarged capillaries filled rapidly and in some loops flow direction changed at irregular intervals. These findings are in contrast to those observed in systemic sclerosis, where generalized microangiopathy with avascular fields, microbleedings, enlarged capillaries and increased transcapillary and interstitial diffusion of the fluorescent dye are typical. In borderline cases capillaroscopy contributes to differential diagnosis of the telangiectatic form of scleroderma and Osler's disease.

Capillaries↗
PubMed1986

Measurement of mesenteric blood flow by duplex scanning.

Ultrasonic imaging combined with a pulsed Doppler unit (duplex scanning) allows the noninvasive assessment of blood flow of the superior mesenteric artery. The changes in mesenteric blood flow associated with a standardized (1000 kcal) food load were measured and the results were compared with blood flow of the left common carotid artery. Twenty healthy subjects (aged 30.1 +/- 5 years) were studied fasting (12.4 +/- 2.6 hours' duration) and six times with a 15-minute interval after the test meal. The diameters of the superior mesenteric artery (0.60 +/- 0.09 mm) and of the common carotid artery (0.61 +/- 0.05 mm) were measured from the B-mode image. The Doppler frequency spectra were used to determine peak systolic, late systolic, and end-diastolic velocity and to compute the mean velocity. Although the flow parameters of the common carotid artery were virtually unaffected by food intake, a steep increase in mesenteric blood flow velocity and volume flow was observed. At rest, blood flow through the mesenteric artery was 6.3 +/- 2.6 ml/sec and 9.5 +/- 2.1 ml/sec in the carotid artery. After the test meal, mesenteric artery blood flow increased significantly (p less than 0.0001) and reached maximal hyperemia (20.3 +/- 7.4 ml/sec) after 45 minutes. The measurement of mesenteric blood flow before and after a test meal characterizes intestinal hemodynamics and should be suitable to evaluate ischemic disease and other disorders that lead to changes of mesenteric blood flow.

Adult↗