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Biomedical subjects

A Bloom

Publications and source records attributed to A Bloom.

At least 55 records · Page 3Linked to original sources
PubMed1983

Embryogenesis of the gingival cyst.

The embryogenesis of gingival cysts derived from the dental lamina was studied histologically in paraffin prepared sections of 10 pairs of human fetal jaws and in individual celloidin sections of human fetal skulls. Cystic degeneration in the dental lamina was noted as early as 10 weeks in utero prior to the separation of the developing tooth bud. Rapid proliferation and growth of such cysts was seen in 15-20 week old embryos during the morphodifferentiation stage of tooth development after fragmentation of the lamina had occurred. Islands, strands and nests of dental lamina epithelium were dispersed into extraosseous locations and demonstrated histomorphologic characteristics similar to odontogenically related epithelium seen in adult gingiva. Dental lamina epithelium appears to have a particular predisposition for cystic degeneration and is probably the source of other neoplasms and hamartomas seen in the gingiva.

Gestational Age↗
PubMed1983

Diabetes, a hypercoagulable state? Hemostatic variables in newly diagnosed type 2 diabetic patients.

37 type 2 diabetic patients with no clinical evidence of retinopathy or vascular disease were studied at diagnosis and following control of hyperglycaemia for evidence of abnormalities of coagulation, fibrinolysis and platelet behaviour. 38% showed hyperactive platelets, demonstrating either in vitro hyperaggregability, circulating platelet aggregates, or raised plasma beta-thromboglobulin levels. 36% showed abnormally raised factor VIII coagulant activity (FVIIIc) levels, though this was mainly in female patients. The mean level of FVIIIc decreased with treatment. Anti-thrombin III (AT-III) levels were decreased, and 33% of the patients had levels less than 80%. In this group AT-III increased following treatment. No abnormalities of fibrinolysis were demonstrated. These findings support the concept that diabetes can be associated with a hypercoagulable state, which is not necessarily dependent on the presence of overt vascular disease, or correlated with the degree of chronic hyperglycaemia (HbA1c levels).

Adenosine Diphosphate↗
PubMed1983

Stimulated osteoperiosteal pedicle grafts in dogs.

This descriptive study compared the healing of mucoperiosteal and "stimulated" osteoperiosteal flaps for the treatment of surgically created periodontal recessions in dogs. Surgically created defects on the canine teeth of 10 healthy mongrel dogs were covered by specially designed, cemented copper bands for 4 weeks (Several maxillary premolar teeth were managed in the same way). A plaque and calculus-promoting diet was fed to the animals during this period. When the bands were removed the diet was altered and an intensive oral hygiene program was instituted. The contralateral tooth, chosen randomly, was utilized for placement of the mucoperiosteal lateral sliding flap and acted as the control. The experimental side was surgically stimulated 21 days prior to elevation of a "stimulated" osteoperiosteal flap for repositioning over the denuded roots. The animals were sacrificed with an overdose of Nembutal and block sections for histologic study were taken at periods ranging from 14 to 50 days. Histologic findings indicate that healing of the stimulated flaps was accompanied by the formation of a relatively short dentogingival epithelium, cementogenesis which varied in amount and type, and new connective fiber insertion into cementum. By contrast, the mucoperiosteal flaps healed with a long dentogingival epithelial relationship and no cementogenesis or connective tissue reattachment.

Alveolar Process↗
PubMed1981

Relationship between intellectual status and reading skills for developmentally disabled children.

The relationship between WISC-R Full Scale IQ and scores on the Woodcock Reading Mastery Tests were explored for 80 developmentally disabled children. While the children's reading skills correlated moderately and significantly with intellectual status, abstract reading skills, e.g., word comprehension, correlated more highly with Full Scale IQ than did concrete ones, e.g., word identification. The development of concrete learning patterns by such children was discussed, with an emphasis on the emotional importance of these learning styles to the children and their families.

Child↗
PubMed1980

Problems in home monitoring of blood glucose.

Two hundred and forty blood glucose readings were made on 5 Glucochek machines by 2 different operators. The results on all machines correlated poorly with equivalent results from an automatic glucose analyser with major discrepancies at all glucose concentrations. There was a wide gap in performance between the 2 operators. Analysis of variance suggested that errors were not only due to inter-operator and inter-machine differences. Possible sources of error were shown to include time of reaction and the amount of blood on Dextrostix. Dextrostix colour changes measured by eye were as accurate as those by Glucochek without the rogue values found at higher glucose concentrations with Glucochek.

Blood Glucose↗
PubMed1980

A comparison of intellectually delayed and primary reading disabled children on measures of intelligence and achievement.

Compared intellectually delayed and primary reading disabled children (N = 64) in respect to WISC-R Verbal-Performance IQ differences and subtest scores on the Woodcock Reading Mastery Tests. First, it was found that the two groups did not differ in respect to overall mean Verbal-Performance IQ differences or in the percentage of children who showed particular directional patterns. Second, the two groups demonstrated more similarities than differences on Woodcock subtest scores. The importance of these findings for the assessment of children's reading problems was discussed.

Achievement↗
PubMed1979

Disposable syringes for insulin injection.

Results of a questionnaire on use of glass syringes among diabetic patients showed considerable variation in methods of keeping the syringes and in the duration of their useful life. Thirty patients took part in an investigation in which each patient used the same disposable syringe in place of the glass syringe for up to two months. No clinical or bacteriological evidence of infection was found. Used in this way, disposable syringes were less expensive than glass syringes. They are lighter than glass syringes, less susceptible to damage, and more easily carried on journeys.

Costs and Cost Analysis↗