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Biomedical subjects

A Besson

Publications and source records attributed to A Besson.

At least 55 records · Page 3Linked to original sources

[Pleuro-pulmonary actinomycosis. Report of 4 cases].

Four cases of pulmonary actinomycosis are reported. Two cases (1978, 1979) were diagnosed on microscopic examination of lung parenchyma excised on suspicion of bronchogenic carcinoma. The third case was diagnosed retrospectively by reexamining the slides of a patient operated on in 1965, who presented with a similar history and chest X-ray. The fourth was diagnosed at autopsy in a patient who committed suicide. Actinomycosis is a rare disease which affects the lung in 15--20% of cases. Despite its name, actinomycosis is not due to a fungus but to an anaerobic gram-positive bacillus. The germ is a saprophyte of the human digestive tract and is very sensitive to penicillins. It may become pathogenic in a compromised host and usually produces cervico-facial lesions which develop by continuity from mouth mucosa. Abdominal or, more rarely, pulmonary lesions are due to ingestion or inhalation of infected material. Chest X-ray appearance of pulmonary actinomycosis mimics that of bronchogenic carcinoma. Actinomyces culture is difficult, and diagnosis is often based on microscopic examination of the surgical specimen only. Antibiotic therapy is a mandatory complement to surgical treatment.

Actinomyces

[Carcinoid tumors, carcinoid syndromes and related tumors (104 cases)].

One hundred and four consecutive cases of carcinoid among 194 APUD-omas (cerebral and gynecological tumours expected) are presented. Localization is as follows: bronchopulmonary (21%), duodenum (5,5%), small intestine (19%), Meckel's diverticulum (5,5%), appendix (39%), colorectal (5,5%), other (4,5%). Average age at diagnosis is very different for each localization of carcinoid tumour, as is prognosis: in our material, 33% of cases had an infiltrative tumour, 17% had lymph nodes metastases and 16% hepatic metastases. All 15 patients with carcinoidosis died but their survival varied considerably in length (from a few weeks to 21 years after the beginning of carcinoidosis). In addition, 3 patients presented with the Zollinger-Ellison syndrome, 2 of them having an atypical or probable form of the MEN I syndrome.

Adult

[Intralobal pulmonary sequestration and tuberculosis superinfection].

Among 16 pulmonary sequestrations observed in 23 years, 3 were associated with pulmonary tuberculosis. A detailed report is given on a 37-year-old man who was found by serendipity to have a right lower sequestration after 6 years treatment for tuberculosis; middle and upper lobe function had already been lost. Two and half years after pneumonectomy, the patient is in good health. Discussion centers on the diagnosis and potential complications of pulmonary sequestrations.

Adult

[Starch peritonitis. Apropos of 13 cases].

First known as an inert and harmless substance, starch powder has been used from 1950 by surgical gloves factories in place of talcum. Its innocuousness is now being denied, but many surgeons still do not know its adverse side effects. 13 cases of glove starch peritonitis, seen between 1971 and 1978, allow the authors to review clinical signs, diagnostic and treatment possibilities as well as the risk of a new operation. To limit the quantity of starch powder introduced into the peritoneal cavity is so far the only mean to prevent this complication and to compel the surgical team to strict discipline.

Adult

[Recurrent massive hemorrhage of the distal part of the digestive tract due to hemorrhagic hereditary telangiectasia].

Massive gastrointestinal bleeding is known to occur in patients presenting the hemorrhagic hereditary telangiectasis condition known as Rendu-Osler-Weber (ROW) disease. Bleeding is most frequent in the fourth decade. Endoscopic coagulation of upper gastrointestinal telangiectatic spots is nowadays possible even in the presence of active bleeding. In the lower digestive tract the naevi are basicallly located on the terminal ileum and the right colon; emergency coloscopic examination is difficult when active bleeding occurs. 10-15% of ROW patients present sudden life-threatening episodes of bleeding. The danger is aggravated through delayed diagnosis as well as difficulty in localizing the hemorrhagic area. Selective angiogram of the three digestive arteries is a safe and efficient method of diagnosing the nature and source of the bleeding. It should be obtained routinely, on an emergency basis, before surgery. Operation includes removal of the involved part of the digestive tract. A specimen angiogram should be obtained during the procedure, to make sure that the bleeding malformation has been removed. Laparotomy without preliminary angiogram is likely to be unsuccessful. An illustrative case is presented.

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