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Biomedical subjects

A Berry

Publications and source records attributed to A Berry.

At least 145 records · Page 8Linked to original sources

There's more to self-esteem than whether it is high or low: the importance of stability of self-esteem.

Study 1 examined the extent to which stability and level of self-esteem predicted cognitive and emotional reactions to interpersonal feedback. Among high self-esteem individuals, instability was associated with acceptance and positive emotions following positive feedback but to rejection and defensiveness following negative feedback. Among low self-esteem individuals, instability was unrelated to reactions to positive feedback but was related to less defensiveness and greater acceptance of negative feedback. Study 2 examined the extent to which variability and importance of specific self-evaluations were associated with instability of global self-esteem. Discussion focused on the roles of level and stability of self-esteem in reactions to evaluations and on the nature of self-esteem instability.

Adolescent↗

Effect of cricoid pressure on ease of insertion of the laryngeal mask airway.

We have evaluated the effects of cricoid pressure on laryngeal mask airway (LMA) insertion after an elective rapid sequence induction in 100 patients allocated randomly to two groups. An attempt was made to insert the LMA after application of cricoid pressure in one group and with no pressure in the other. The anaesthetist was blinded to the application of cricoid pressure. Insertion was successful in 45 of 50 patients in the cricoid pressure group and in 49 of 50 patients in the non-cricoid group (P < 0.1) We discuss the implications of these findings for failed intubation in the nonfasted patient.

Adolescent↗

Molecular analysis of an allozyme cline: alcohol dehydrogenase in Drosophila melanogaster on the east coast of North America.

Clines may either be selectively maintained or be the by-product of nonadaptive processes related to population structure and history. Drosophila melanogaster populations on the east coast of North America show a latitudinal cline in the frequencies of two common electrophoretically distinguishable alleles at the alcohol dehydrogenase locus (Adh), designated Adh-S and Adh-F. This cline may either be adaptive or an artifact of a possible recent dual founding of North American D. melanogaster populations in which frequencies of Adh alleles differed between founder populations. By means of a high resolution restriction-mapping technique, we studied the distribution of 113 haplotypes derived from 44 polymorphic DNA markers within the Adh region in 1533 individuals from 25 populations throughout the cline. We found significant clinal differentiation at the polymorphism determining the mobility-difference causing amino acid replacement between Adh-F and Adh-S alleles. Hitchhiking was limited, despite extensive linkage disequilibrium, and other sites did not vary clinally. Such a pattern of differentiation implies that selection is responsible for the cline. To investigate whether selection acts only on the Adh-F/S site, we performed a "selective equivalence" test under the assumption that all variability within the specified allelic class is selectively neutral. This revealed selective equivalence among Adh-S-bearing haplotypes, whose frequencies showed no differentiation throughout the cline, implying high levels of frequency-homogenizing gene flow. Geographical heterogeneity among Adh-F-bearing haplotypes implied the action of selection on one or more additional variants in linkage disequilibrium with Adh-F. In a further study of a subset of the data (n = 1076 from 18 populations), we found a combined insertion/deletion polymorphism, designated delta 1, located in the 5' adult intron and in linkage disequilibrium with Adh-F, to show more marked clinal variation than Adh-F/S. Although the unequivocal identification of the precise target(s) of selection requires further study, we suggest that clinal selection may be acting epistatically on the Adh-F/S and delta 1 polymorphisms.

Alcohol Dehydrogenase↗

Laryngeal mask airway insertion. A comparison of the standard versus neutral position in normal patients with a view to its use in cervical spine instability.

The ease of insertion of the laryngeal mask airway with the patient's head in the standard position and the neutral position was compared, in a study of 80 healthy patients. Successful insertion was assessed by fibreoptic bronchoscopy and the functioning of the airway. In terms of function the successful insertion rate for the standard position was 100% (40/40) and for the neutral position 95% (38/40). There were no significant differences in scores as assessed by fibreoptic bronchoscopy. The laryngeal mask airway may have a role in the management of some patients with cervical spine instability, although confirmation of this ultimately depends on the results of outcome studies.

Anesthesiology↗