Biomedical subjects
A Berman
Publications and source records attributed to A Berman.
J.B.A. Chevallier, pharmacist-chemist: a major figure in nineteenth-century French public health.
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Halo nevus with exceptional clinical features. Apparent arrest of nevus cell degeneration and return of pigment to halo.
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Failure of flat warts to recur in electrosurgically altered skin.
Two men with recurring flat warts in the beard area have been observed for five and ten years, respectively. Both have depigmented patches at sites where flat warts had been removed by electrosurgical destruction. Crops of new warts appear periodically. These develop always on the normally pigmented skin and have never been found in the leukodermic areas. Flat warts have been observed repeatedly at the margin of depigmented and normal skin; these invariably enlarge toward the normal skin and never encroach on leukodermic skin. The failure of flat warts to develop in electrosurgically treated skin, if substantiated, would indicate that local tissue factors influence resistance to development of flat warts. Perhaps this phenomenon is similar to that reported in Darier's disease, where partial-thickness excision of involved skin has resulted in resistance to recurrent disease.
Depigmented haloes associated with the involution of flag warts.
Depigmented haloes developed around involuting flat warts in two patients whose warts were treated with a 6% salicylic acid-propylene glycol gel formulation. The clinical picture was indistinguishable from that seen in halo naevus.
Use of 59Fe for sheep erythrocyte kinetic studies.
Erythrocyte (RBC) survival time as determined by in vivo 59Fe-labeled RBC in 6 adult sheep was 111.7 (SEM +/- 8.4) days. The plasma clearance (T/2) of 59Fe was 148 (+/- 17.3) minutes and the maximum RBC uptake of 59Fe was 52.4% (+/- 3.6%). Plasma iron turnover rate was 0.356 (+/- 0.016) mg/kg/24 hours, and RBC iron turnover rate was 0.186 (+/- 0.016) mg/kg/24 hours. Blood volume measurement was 53.5 (+/- 3.9) ml/kg of body weight.
Flat warts undergoing involution: histopathological findings.
Patients with multiple flat warts were observed during the period of involution, shortly before regression of the warts. The histopathological process was characterized by mononuclear cell infiltration around subpapillary blood vessels, exocytosis of mononuclear cells into the epidermis, and a spectrum of degenerative epidermal changes that culminated in focal areas of necrosis within the epidermis. Lesions near the end stage of involution did not show the histopathologic features of flat warts. The mononuclear cell-associated injury to the epidermis resembles that seen in delayed cutaneous hypersensitivity responses and suggests that regression of flat warts may be due to a cell-mediated rejection reaction.
Some observations on the report of the Study Commission on Pharmacy.
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American hospital pharmacy: a bicentennial perspective.
The history of American hospital pharmacy is reviewed. The development of hospital and health care, the evolution of medical and pharmaceutical sciences, and the growth of pharmacy as a profession are described as prologue to the development of hospital pharmacy. The early development of hospital pharmacy in the 1920s and 1930s, the contributions of Edward Spease and Harvey A. K. Whitney, and the necessity of hospital pharmacy services are discussed. The clinical pharmacy movement is reviewed in terms of its potential for changing the nature of pharmacy practice.
Effects of natural winter conditions on thermoregulation in shorn and unshorn sheep.
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The use of 51Cr for sheep red blood cell survival studies.
The red blood cell half-life as determined by 51Cr-labelled autologous cells in five adult sheep was 13.7 days. In contrast, the red blood cell life span measured by cohort 59Fe-labelling in six adult sheep was 111.7 days. The rapid loss of 51Cr-activity from the circulation appears to result from rapid elution of the label from the circulating red cells. 51Cr does not appear to be a suitable isotope for erythrokinetic studies in sheep.
Homoeothermy and growth rate in the fowl.
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Reliability of perceptual-motor laterality tasks.
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The Pharmacopoeia Reformata of London (1744) and its anonymous author.
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The problem of assessing cerebral dominance and its relationship to intelligence.
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Thermoregulation in intensively lactating cows in near-natural conditions.
1. Thermoregulatory reactions of lactating cows (33 kg milk/day) have been measured in summer (25-39 degrees C) and in winter (9.5-24 degrees C) at 3 hr intervals, during four nychthemeral (24 hr) cycles in each season.2. The rectal-to-tympanic temperature gradient increased with rising body temperatures. The seasonal changes were larger for the rectal temperatures than for the tympanic membrane temperatures. These and the significantly lower correlations between rectal temperatures and regulatory responses suggest that in the ruminant rectal temperatures are considerably affected by rumen metabolism and do not represent a reliable index of the regulated temperature.3. In the winter the regulatory responses were correlated with skin temperatures only. In the summer responses were correlated with both skin and tympanic temperatures, excepting for skin water loss.4. The seasonal difference in the effects of skin and tympanic temperatures on regulatory responses was associated with a small change in mean tympanic temperature. The twofold larger nychthemeral fluctuation in the summer tympanic temperature is suggested to cause the seasonal difference in the thermoregulatory mode.5. The winter range of nychthemeral fluctuations in tympanic temperature suggests a range of permitted core thermolability. A wider permitted core thermolability in summer is unlikely to be a mechanism of acclimatization in the cow.
Thermoregulatory control in cattle exposed to the natural climate.
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