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Biomedical subjects

A Berger

Publications and source records attributed to A Berger.

At least 505 records · Page 28Linked to original sources

[The accessory brachial tendon--a rare cause of pronator teres syndrome].

The pronator syndrome is caused by a compression of the median nerve at the level of the elbow. In the case presented bizonal compression of the nerve was seen, first by the lacertus fibrosus, second by an isolated abnormal tendon of the brachialis muscle. The treatment, therefore, includes the early and extensive operative exploration of the nerve, the resection of all compressive structures and sometimes interfascicular neurolysis and transposition of the nerve anterior to the pronator teres, when the nerve is in a badly scarred bed.

Adolescent↗

[Diagnosis and therapy of psychogenic paralyses in the hand region].

Beside the importance of its prehensile function the human hand plays an essential role in the conveyance of expression. Manual gestures support the mimic and confirm the spoken word. Based on the psychofunctional connection between mimic and gesture the hand becomes an outlet for psychogenic disorders. The resultant projection of emotional processes into motor disorders has been a matter of conjecture etiologically. Psychogenic manifestation in isolated motor disorders of the hand is considered to be either a functional nervous disorder or a focal dystonia. In comparison to the conversion phenomena reported up until now, in which flexor muscle units of the hand are involved with increased muscular activity (spasm), the cases presented here are characterized by a functional motor disorder manifested as an isolated paralysis of a selective extensor muscle unit (M. extensor pollicis longus) of the hand. After a multidisciplinary approach including clinical morphology, neurology, EMG and psychiatry the final diagnosis of a psychogenic paralysis of the hand is made using direct electro-stimulation of the neuromuscular unit with a needle electrode under simultaneous elimination of the psychic influence (general anesthesia without muscular relaxation). Through such confirmed motor inactivity the psychic genesis of the clinically existing paralysis is proven. Through immediate introduction of a multimodal therapy including physical and psychiatric treatment psychogenic paralyses of the hand can be restored totally.

Adolescent↗

[Hyperbaric oxygenation in burns].

Standardised third degree burn injuries were produced in guinea pigs and a standardized pseudomonas aeruginosa infection model was used. Therapy with oxygen under high pressure (OHP) was initiated for not experimentally infected burn wounds and for wounds contaminated with a constant number of bacteria from a certain pseudomonas aeruginosa strain. The healing process was documented by wound area determination, histological examination, and bacteriological evaluation. Not treated uninfected wounds showed better results than the ones that were treated with OHP. Infected burn wounds also healed better when they were not treated than the wounds in which OHP therapy was initiated with some delay. The immediate and consistent application of OHP therapy led to a significantly improved healing of burn wounds infected with pseudomonas aeruginosa.

Animals↗

Homozygous protein C deficiency manifested by massive venous thrombosis in the newborn.

We studied a family in which two infants had died with massive venous thrombosis shortly after birth. Protein C antigen was undetectable by immunologic assays of plasma available from one infant. (Protein C is a potent naturally occurring anticoagulant that inactivates activated coagulation factors V and VIII). The parents, who were first cousins, both had partial protein C deficiency. Reduced protein C levels were also observed in 12 of 25 additional family members. None of the partially deficient family members (age range 4 to 70 years) had thrombotic episodes. Our data support the view that hereditary protein C deficiency is an autosomal disorder in which the homozygous state may be manifested by the virtual absence of plasma protein C and by fatal thrombosis in the neonatal period.

Adult↗

Clinical judgments of easy vs. difficult clients by counselor trainees.

Thirty-one counselor trainees viewed videotapes of two actors portraying either an easy client (one who expressed intrinsic motivation for help, responded openly to questions and spontaneously elaborated on responses) or a difficult client. Trainees made 11 ratings of client functioning, likely response to treatment, and personal reactions to client. As expected, clients with a difficult interpersonal style were not regarded as more psychologically disturbed, but were rated as having less potential for change and less ego strength. They were rated as less likely to attend the next interview or to complete counseling and less likely to respond well to counseling. They also were less well-liked. Auxiliary analyses indicated that minority counselors (N = 9) appeared more optimistic about the results of counseling, though they anticipated equally much difficulty in working with the clients. A single interaction effect indicated that white counselor trainees saw less potential for change in the difficult vs. easy clients; minority Ss made no such distinction.

Adult↗

[Positioning, care and physical therapy in severely burned patients].

Positioning, medical care, and physiotherapy for severely burned patients represent essential parts of the treatment in the complete plan of full rehabilitation and resocialization. From the beginning an individual programme for each patient must be organized in joint planning with the physio- and ergo-therapists and be carefully controlled.

Burns↗

Effects of burns on amino acid levels in rat plasma, liver and muscle.

In this study the influence of a severe catabolic situation (scalding and nitrogen deprivation) on amino acid (AA) metabolism was investigated in an experimental rat model. Scalding of 25 per cent of the total body surface area (TBSA) and hypocaloric alimentation (5.6 kcal per 100 g rat per day, no nitrogen) resulted in mean daily nitrogen losses of -0.27 +/- 0.3 g. Compared to anabolic growing rats this nitrogen catabolism significantly reduced the total free AA content of muscle (-47 per cent, P less than 0.001) and liver (-39 per cent, P less than 0.001). The total plasma AA concentrations were slightly increased in catabolic rats (+10 per cent). In catabolic rats muscle glycine concentrations dropped significantly (-79 per cent, P less than 0.001), while glutamine concentrations decreased by 22 per cent, which was not significant. Branched chain AA and phenylalanine were significantly elevated both in muscle and in plasma. Scalding and nitrogen depletion in rats leads to characteristic changes in plasma, muscle and liver AA concentrations, which are comparable to the results obtained in catabolic patients. However, the low muscle glycine concentrations in burned rats differ from the clinical observations where glutamine rather than glycine concentrations in muscle tissue are reduced. The rat model seems to be well suited for studying the influence of various therapeutic approaches such as different forms of parenteral nutrition or hormonal substitution on nitrogen catabolism.

Amino Acids↗

Free jejunal graft for reconstruction of oral, oropharyngeal, and pharyngoesophageal defects.

A free jejunal graft was used either as a patch or as a conduit in 40 cases of reconstruction of the oral cavity, hypopharynx, and upper esophagus. Compared with previous intraoral reconstructive techniques using skin or myocutaneous flaps, one-stage free jejunal grafts result in low morbidity, rapid postoperative recovery, and no additional head and neck scars. Because of secure vascularization, the retention of temporary mandible implants is made safer. In addition to tongue reconstruction, facial contouring can also be achieved by the use of mesenteric fatty tissue. The well-vascularized physiologic lining created by utilizing the jejunal graft is highly resistant to mechanical stress and postoperative radiation therapy.

Adolescent↗

[The free jejunal graft for the reconstruction of the hypopharynx and cervical esophagus].

The free jejunal transfer for primary reconstruction of the cervical oesophagus after laryngo-pharyngectomy was described more than 20 years ago. Its popularity as a surgical method has increased in recent years with improvement in microsurgical techniques. Tumour resection and preparation of the jejunal graft are performed synchronously by two surgical teams. After suturing the graft into the defect the mesenteric vessels are usually anastomosed to the superior thyroid pedicle. In this series four patients are presented, in three there were no complications, in the fourth a fistula developed despite adequate vascularisation of the transfer. The jejunal graft has proved to be a good functional replacement for the cervical oesophagus. Experience in other series have shown the risks of necrosis, fistulae, stenosis and abdominal complications to be minimal.

Adult↗

[Glycosaminoglycans in Dupuytren contracture].

Connective tissue from specimens of Dupuytren's disease showed higher contents and altered distribution patterns of glycosaminoglycans. Increasing chondroitin sulphate concentrations as well as increasing proportions of 6-sulphated galactosamines were found to be the characteristic changes.

Connective Tissue↗

[Joint saving forearm replantation using pedicled latissimus dorsi island flap].

In a case report, replantation of a subtotally amputated forearm at the elbow region is described. The elbow joint was reconstructed. At the end of the operation a huge soft tissue defect remained leaving the vein grafts unprotected. Using a latissimus dorsi myocutaneous island flap, the soft tissue defect was covered and the function of the biceps muscle restored.

Amputation, Traumatic↗