Biomedical subjects
Publications and source records attributed to A Benvenuti.
Two cases of tularemia caused by direct contact with an infected hare are described. Recent epidemiological discoveries about the disease are reported with reference to other known foci in Tuscany and the measures taken to control and isolate the infected areas.
The authors investigated the tissue around a failed knee prosthesis which had a metal-on-metal bearing made of chromium-cobalt-molybdenum alloy. Histological examination and the quantitative analysis of metallic particles found in the bone marrow (by fluorescent spectrometry and laser microsound) provided a detailed picture of the quantity, nature and distribution of the wear debris. The type and nature of the tissue response to the presence of the metal particles was determined by fluorescent microscopy and microradiography.
An investigation on the tensile properties of osteonic lamellae whose fiber bundles have an almost transversal spiral course has been carried out, using samples obtained from alternately structured osteons by applying a procedure described in detail by Ascenzi et al. (1973). A very sensitive microwave extensometer based on cavity and pulse technique was employed in order to record the tensile curve from each lamellar sample. The inhomogeneity in thickness within, and between, single lamellae has ruled out any form of comparison between the curves recorded for ultimate tensile strength and modulus of elasticity. This result is in agreement with the morphological finding that there is usually a wide, continuous range of variation in thickness even along the length of single osteonic lamellae.
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The analysis of mortality in urban settings for the Cities of Florence (1991-95) and Leghorn (1987-95), based on data from the Tuscany Longitudinal Study, is reported in the present paper. The data came from a census-based cohort study, all residents at the census day 1981 (Leghorn) or 1991 (Florence) being enrolled and followed-up by automated procedures of record-linkage. The cause of death certificate had been eventually collected by the Regional Mortality Register. For each city, internally standardized mortality ratios (SMR) had been calculated by sub-urban areas (city sectors or wards). The analysis was restricted to age groups > 15 years to have interpretable results on socio-economic variables derived from census questionnaires. Bayesian estimates (Besag, York e Mollié) of mortality relative risks had been calculated to overcome extra-variability of SMRs. In the city of Florence two wards showed about 10% excess risk for overall mortality. In the city of Leghorn one sector was at higher risk while one showed a significant lower mortality. For both cities such risk gradients were still present after adjustment for deprivation index at individual level.
We evaluate the persistence of social inequalities in overall mortality or mortality by causes (lung cancer, liver cirrhosis; AIDS and overdose) in the Tuscany Longitudinal Study (SLTo), a record linkage-study on the census population identified at the 1981 and 1991 censuses in Leghorn (1981: 175,741 subjects; 1991: 167,512 subjects), and 1991 in Florence (403,294 subjects), Central Italy. The census data allow an evaluation of socio-economic status of each subject, using variables such as education or occupation, or constructing indexes inclusive of deprivation indexes. Follow-up is from the census up to 1995 and for specific causes of death from 1987 (Leghorn) or 1991 (Florence). Estimates of risk are computed comparing rates of mortality among socio-economic groups, by means of poisson regression models, or by means of Standardized Mortality Ratios using the indirect method. The causes of deaths have been selected mainly because explained by known and strong determinants. As far as overall mortality, the results suggest the persistence of gradients by social class, more often negative among males. Mortality from lung cancer has a strong negative social class gradient among males, and a divergent gradient among women in the two towns, which is interpreted as the effect of a different prevalence of smoking by period, social class and sex. High RRs among lower socio-economic groups have been detected for liver cirrhosis mortality. Excess mortality of AIDS and overdose, an expression of the recent drug crisis, concentrates on the lower social strata and in young adults. Whereas mortality from AIDS has been detected among both sexes, deaths from overdose are occurring among males only. Being AIDS and overdose recent diseases, they stress the persistence of social inequalities over time.
Some experiments of varietal comparison of various cultivars of rapeseed were carried out, determining the productivity, the oil yield and the analytical characteristics of the oils. Moreover the effects of nitrogen fertilization on the seed production and on oil characteristics were tested. The achieved results have pointed out that, referring to the chosen environment, the cv. "Matador" and "Leonessa" show the highest seed and oil productions, whereas oils extracted from the cv. "Sinus", "Erusine" and "Sinera" contain the minor quantities of erucic acid. It seem that nitrogen fertilization exerts no appreciable influence on rapeseed oil composition. The possibility of the utilization of cv. with law content in erucic acid confirms the practical validity of the cultivation of rapeseed as on oil plant.
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