Search PubMed⌕ Search

Biomedical subjects

A Benosman

Publications and source records attributed to A Benosman.

33 records · Page 2Linked to original sources
PubMed2000

[Mature teratome of the mediastinum].

STUDY AIM: The aim of this retrospective study was to report a series of 12 cases of mature teratoma of the mediastinum operated during a 10-year period in the same center. PATIENTS AND METHOD: From 1990 to 2000, 12 patients (7 females and 5 males with a mean age of 32 years) were operated for mature mediastinal teratoma. Chest pain was present in 10 cases; cough, dyspnea and septic episodes were present in 5 cases and X-ray detected the mediastinal tumor in 10 cases. CT scan showed a tumor with liquid and fatty components and calcifications in 5 out of 9 cases. Tumors were resected via a posterolateral thoracotomy in 11 cases and an anterior thoracotomy in one case, associated with pneumonectomy in 1 case, basal segmentectomy in 1 case and thymectomy in 1 case. RESULTS: There were no postoperative deaths. Morbidity included 2 phrenic nerve palsies, 1 pyothorax after pneumonectomy, 1 case of bleeding and 1 pleural effusion. No recurrences have been observed with a follow-up of 5 to 87 months. Nine of the 10 tumors reviewed by pathologist contained multiple tissue components and one only contained a single tissue. CONCLUSION: Mature teratomas are usually detected in young patients: they are usually located in the middle part of the anterior mediastinum and are only diagnosed by pathologic examination of the specimen. They have an excellent prognosis when tumor resection is complete and in the absence of immature tissue in the tumor.

Adolescent↗
PubMed2000

[Nephrobronchial fistula: a case report].

Nephrobronchial fistulas following pyonephrosis associated with urolithiasis are a rare occurrence. The possibility of severe problems arising during surgery should be taken into considerations; both the surgeon and the anesthetist should be fully informed of the specific risk factors involved. A favorable outcome mainly depends on the appropriate treatment and timely management of any thoracic complications. Although this rare pathology has been described in detail in the literature, the problems encountered during anesthesia and surgery have not been fully reported. This study therefore provides new data, as a case has been reported of a 38-year old female who underwent surgery for pyonephrosis; disease management and prognosis problems have been discussed.

Adult↗
PubMed1999

[Pulmonary aspergilloma: results of surgical treatment. Report of a series of 206 cases].

STUDY AIM: The aim of this retrospective study was to report the results of the surgical treatment in 188 patients operated on for pulmonary aspergilloma in a series of 206 patients observed in Morocco. PATIENTS AND METHOD: From 1982 to 1998, 206 patients were treated for pulmonary aspergilloma in the same hospital; 188 were operated on and surgery was contraindicated in the other patients with general or respiratory failure. Hemoptysis was the main symptom, present in 190 patients (92%). Surgery was performed on principle with 108 lobectomies, 38 segmentectomies, 18 lobectomies and segmentectomies, 21 pleuropneumonectomies and 3 thoracoplasties. RESULTS: Postoperative complications occurred in 36% of the patients including: pyothorax (n = 15), hemothorax (n = 10), rehabitation defects (n = 17) and respiratory failure (n = 10). Reoperation was necessary in 6 patients. Postoperative mortality rate was 6.4% (12 patients including 5 treated by pleuro-pneumonectomy). CONCLUSION: The surgical treatment, in spite of its high morbidity, has to be proposed to all patients with pulmonary aspergilloma, even in asymptomatic patients when there is no surgical contraindication. Pleuropneumonectomy is a very high risk procedure and its indications must be restricted. Thoracoscopy was rarely performed in this series.

Adolescent↗
PubMed1999

[Inflammatory pseudotumor of the lung. An anatomoclinical study of a case report].

One solitary pulmonary nodule was observed in a 47-year-old woman with history of right thigh liposarcoma 1 year before. Histological examination of the pulmonary specimen excluded liposarcoma metastasis and revealed an inflammatory pseudotumor. These unusual lesions with an excellent prognosis may exhibit, as in our case, atypical radiologic features and nuclear atypia, making the diagnosis difficult with malignancy.

Diagnosis, Differential↗
PubMed1999

[Descending necrotizing mediastinitis. A case report].

Descending necrotizing mediastinitis which may occur as a complication of neglected oropharynx infection is an uncommon disease, although it is lethal in most cases. Trismus and dyspnea are usual with palpable crepitation located in the cervico-thoracic area. Early diagnosis can be confirmed with accuracy by CT scan. Treatment is based on early mediastinal drainage by cervical approach, intravenous antibiotics and reanimation. The reported case had a favorable outcome.

Adult↗
PubMed1999

[Malignant small-cell thoracic pulmonary tumor (Askin tumor)].

We report 4 cases of malignant thoraco-pulmonary small-cell tumors (Askin tumor). Only two cases were operated. We emphasize the difficult histological diagnosis and demonstrate the importance of complete removal for survival. Prognosis remains poor.

Adolescent↗
PubMed1999

[Hydatid thymic cyst. A case report].

Hydatid thymic cyst is exceptional. The diagnosis is suspected by radiology and epidemiology. Serology tests provide variable results and surgery is the only treatment. We report a case of thymic hydatid cyst in a 20-year-old man who had no other localizations. Diagnosis was confirmed at surgery and by histology.

Adult↗
PubMed1997

[Chronic recurrent multifocal osteomyelitis in children].

We have studied retrospectively a series of 10 children presenting with chronic multifocal osteomyelitis (8 girls, 2 boys, 7 to 16 years). All patients had plain films, bone scintigraphies and histological studies. Three had CT scan and/or MRI. compared with literature data, we observed only one case of palmoplantar pustulosis and only 2 cases of lysis of the medial extremity of the clavicle; in addition, we report one case of lateral extremity of the clavicle and 2 vertebral locations. The radiological pattern was typical: at the beginning of the disease, plain films showed lytic areas which became progressively osteosclerotic with enlargement of the bone. In all the cases, bone scintigraphy revealed high uptake areas which were often infraclinical. The diagnosis was delayed from 3 months to 3 years. This emphasizes the difficulty of the diagnosis which relies on the association of clinical, biological and radiological elements. Biopsies are required to rule out an infectious bacterial osteomyelitis or a tumoral process. The pathogenesis of OCMR remains unknown, but the relation with the SAPHO (synovitis, acne, pustulosis, hyperostosis, osteitis) syndrome is general accepted because of the similar features of the osteitis. The long term follow up appears to be uncertain 6 of our patients are still symptomatic after five years despite anti inflammatory treatment.

Adolescent↗
PubMed1996

[Visceral and cutaneous leishmaniases in the north. Retrospective study of cases diagnosed in the Rabta Hospital of Tunis].

The authors report a retrospective study of 50 cases of infantile visceral Leishmaniasis (April 1994-April 1995), and 53 cases of sporadic cutaneous Leishmaniasis of north-Tunisia (August 1990-July 1994), diagnosed in parasitology laboratory of Rabta hospital. They insist on the recrudescence and the extension of the distribution geographical area of these two clinical forms of human leishmaniasis observed in Tunisia.

Adolescent↗
PubMedDate not supplied

Effects of triterpenes from the stem bark of Dysoxylum cauliflorum on a non-small-cell bronchopulmonary carcinoma cell line (NSCLC-N6).

Six triterpenoids and one sesquiterpene were isolated from the ethanolic extract of the stem bark of Dysoxylum cauliflorum. Their structures were determined from 1D and 2D NMR and mass spectral data. Only compound 1 was cytostatic. Kinetic studies with ethyl eichlerianoate 1 demonstrated that this growth arrest was irreversible and cytofluorimetric analysis with compound 1 showed a complete block of NSCLC-N6 cells in the G1 phase. These events were related to a terminal maturation induction.

Antineoplastic Agents↗
PubMedDate not supplied

Hydatid cyst: an unusual disease of the mediastinum.

BACKGROUND: Hydatid cystic disease is still a significant clinical problem in endemic countries, particularly in Morocco. Mediastinal localization is very rare. We report our surgical experience with this particular lesion. PATIENTS AND METHODS: In a retrospective review of the last ten years (1990-1999), we had seven cases of mediastinal localization out of total of 2332 (0.3%) intrathoracic hydatid cysts treated in our service. Imaging investigation consisted of chest x-ray and computed tomography. All diagnoses were confirmed peroperatively macroscopically and for some lesions, histologically. RESULTS: Complete resection of the cyst was performed in six cases. In one case, a small part of the wall intimately adherent to the superior vena cava was left in place. There were no complications, mortality or recurrence. CONCLUSION: Hydatid cysts can be found in many different sites in the body. Whenever possible, surgical management is the best treatment but extensive resection should be avoided. Medical treatment as an adjunct to surgery is indicated when there is a risk of dissemination.

Adult↗