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Biomedical subjects

A Bener

Publications and source records attributed to A Bener.

At least 73 records · Page 4Linked to original sources

Injury mortality and morbidity among children in the United Arab Emirates.

UNLABELLED: The objective of this study was to identify the major causes of accident mortality and morbidity among children (0-14 years) in Al-Ain, United Arab Emirates (UAE). A retrospective descriptive study was set in the Al-Ain Hospital and Preventive Medicine Department, Ministry of Health, Al-Ain. Subjects were all patients aged 0-14 years who were seen at Al-Ain Hospital for injury during the 12-month period January to December 1995, and all recorded deaths aged 0-14 years in Preventive Medicine Department from 1980 to 1995. RESULTS: Mortality: 301 children (69.4% males, 30.6% females) died after accidents from 1980 to 1995. UAE citizens and other Arabs represented the majority of deaths. Most mortality (28.6%) occurred in the 1-4 year age group. Head and neck injury was the major type of injury causing death (57.5%). The most common cause of accidental death was road traffic accidents (boys 67.1%, girls 60.4%), followed by drowning and burns (8%). Morbidity: Pediatric trauma cases seen during 1995 totaled 17,498, representing one third of all patients attending the Hospital Emergency Room. About 70% of encountered injuries occurred among boys; 44.6% of cases were UAE citizens. The most common trauma type was contusion (40.2% boys; 40.6% girls), the most common type of trauma in boys and girls (30.4% and 36%, respectively). In the age group <5 years, the most common causes of trauma were fall (41.1%), blunt trauma (38.7%) and burns or scalds (64%), while in 5-9 year olds, the most common cause was road traffic accidents (40%). Finally, in 10-14 year olds, the most frequent causes were traffic accidents (32.8%) sharp objects injuries (38.3%), and fights and sporting (28.9%). CONCLUSION: More boys than girls presented with injury and the majority were nationals. Road traffic accidents mainly occurred in children over 10 years.

Accidental Falls↗

Respiratory symptoms and lung function in garage workers and taxi drivers.

The aim of this study was to determine the prevalence of some respiratory symptoms and possible diseases among occupationally-exposed garage workers and taxi drivers. This study involved 158 garage workers and 165 taxi drivers, matched for age, sex, nationality and duration of employment. The mean age of 158 Indian subcontinent garage workers was 34.4 +/- 10.4 years; their mean height and weight were 167.7 +/- 6.6 cm and 72.0 +/- 12.3 kg respectively, and the mean duration of employment garage workers was 8.8 +/- 7.6 years. The mean age of 165 Indian subcontinent male taxi drivers was 34.5 +/- 7.7 years; their mean height and weight were 168.7 +/- 6.1 cm and 71.3 +/- 12.6 kg respectively; and the mean duration of employment was 7.5 +/- 5.4 years. The data on chronic respiratory symptoms showed that garage workers had higher prevalence of symptoms than taxi drivers being significantly greater for chronic phlegm, (p < 0.007); dyspneoa (p < 0.001); and sinusitis (p < 0.03). A higher prevalence of all acute symptoms was recorded in garage workers than in taxi drivers, although the differences were significant only for throat (p < 0.02), hearing problems (p < 0.002); nose (dryness, bleeding and secretion) (p < 0.008); and low back pain (p < 0.05). Almost all forced spirometric tests in the exposed garage workers were lower than in taxi drivers. The results of stepwise multiple regression analysis showed that only phlegm, sinusitis, hearing problems, nasal catarrh, throat, low back pain, smoking and FEF25-75, variables were statistically significant predictors as risk factors. In conclusion, the present study suggests that a high prevalence of respiratory symptoms is associated with exposure to motor vehicle exhaust emission in garage working places. Long-term working as garage workers in the United Arab Emirates (UAE), may be associated with the development of chronic respiratory symptoms and have effects on their daily life and health.

Adult↗

The prevalence of Toxoplasma gondii specific IgG and IgM antibodies in blood donors in Al Ain, United Arab Emirates indicates a potential risk to recipients.

The results of a prospective cross-sectional study on the anti-toxoplasma IgG and IgM specific antibody profile among blood donors in Al Ain United Arab Emirates are presented. The overall infection rate was 34%. Based on IgM specific antibody positive rate, acute toxoplasmosis was evident among 3% of the blood donors studied. The theoretical implications of these findings are discussed.

Adolescent↗

United Arab Emirates population data on three DNA tetrameric short tandem repeat loci: HUMTHO1, TPOX and CSF1PO--derived using multiplex polymerase chain reaction and manual typing.

Allele and genotype frequencies for three tetrameric short tandem repeat (STR) loci: HUMTHO1, TPOX, and CSFIPO, were determined in a United Arab Emirates (UAE) national population sample (n = 119). The loci were amplified simultaneously and the PCR products were separated in polyacrylamide DNA sequencing gels. Detection of the DNA fragments was accomplished using silver staining. Allele designations were determined by comparison to an allelic ladder. One allele at each locus was sequenced to confirm the nature of the repeats and their number. Alleles at the HUMTHO1 and TPOX loci were distributed bimodally, while CSF1PO showed unimodal distribution. The observed heterozygosities were 76% for HUMTHO1, 64% for TPOX, and 71% for CSF1PO. No deviation from the Hardy-Weinberg expectations was observed in the genotype distribution for the loci TPOX and CSF1PO, but the HUMTHO1 locus did depart from HWE based on the likelihood ratio and the exact test. No correlation was detected between the alleles at any of the three pairs of loci. The allelic frequency data of these three loci in the UAE population sample can thus be used in human identity testing.

DNA↗

Sexual dysfunction among type II diabetic men: a controlled study.

This was a primary health care (PHC) study aiming at the investigation of the prevalence and nature of sexual dysfunction among a sample of type II diabetic men, in comparison with the control groups of hypertensive men and apparently healthy men with no chronic medical illness. Subjects were assessed by PHC physicians using a sexual dysfunction semistructured questionnaire and a questionnaire designed for medical history and sociodemographic data. Clinical assessments for peripheral vascular disease and peripheral neuropathy were carried out for the diabetic group only. The estimated high prevalence rate of sexual dysfunction among the diabetic group (89.2%) was significantly greater than the hypertensive group (43.6%), and the apparently healthy group (16.7%). The commonest clinical presentations of sexual dysfunction among the diabetic men were impaired morning and spontaneous erections, erectile weakness, and ejaculatory disturbances. Lesser common presentations were reduced sexual interest and complete erectile failure. There were no significant associations between the sexual dysfunction and clinically obvious physical complications of diabetes, or factors that might affect sexual functioning (i.e., alcohol or drug misuse or marital disharmony). However, the validity of these results is questioned due to the small numbers used for statistical analysis.

Adult↗

Consanguineous marriages in the United Arab Emirates.

This study examines the frequency of consanguineous marriage and the coefficient of inbreeding in the United Arab Emirates (UAE). The study was conducted in Al Ain and Dubai cities between October 1994 and March 1995. A sample of 2033 married UAE females aged 15 years and over participated. The degree of consanguinity between each female and her spouse, and the degree of consanguinity between their parents were recorded. The rate of consanguinity in the present generation was high (50.5%) with a coefficient of inbreeding of 0.0222. The commonest type of consanguineous marriage was between first cousins (26.2%). Double first cousin marriages were common (3.5%) compared to other populations. The consanguinity rate in the UAE has increased from 39% to 50.5% in one generation. The level of consanguinity was higher in Al Ain (54.2%) than in Dubai (40%).

Adult↗

Socioeconomic factors in the families of children with lymphoid malignancy in the UAE.

Children of subcontinental (Indian and Pakistani) origin living in the United Arab Emirates (UAE) have previously been shown to have a higher relative frequency of ALL when compared to other ethnic groups. To analyze the possible effect of social class in this difference, a study of socioeconomic factors was conducted through personal interviews with the families of 115 children with lymphoid malignancies. The patients belonged to three ethnic groups: (1) UAE; (2) other Arabs; and (3) Indian subcontinent. UAE parents had the highest income and number of rooms in their house, but the lowest level of education. Occupational categories were significantly different for the three ethnic groups. While 41% of the UAE fathers worked in the army or the police, the majority of Arab and subcontinental fathers worked as government administrators or professionals. UAE families had the highest number of children in the family, subcontinental families the lowest. The number of children per family was inversely related to the parents' education level. Multiple regression analysis showed parental education level and house size to be significantly associated with ethnicity, while parental consanguinity was significantly associated with the diagnosis of lymphoma. It is difficult to define social class in the UAE population. While income and property ownership would place the UAE nationals in the highest category and the subcontinental group in the lowest, education level and occupational category would place the Arab and subcontinental groups higher. The smaller family size and higher education level in subcontinental families corresponds to the previously found higher relative frequency of ALL in this ethnic group and could lend support to the possible infectious etiology of the disease.

Birth Order↗

Breastfeeding and supplemental feeding for neonates in Al-Ain, United Arab Emirates.

A prospective cohort study was carried out to determine the factors affecting initiation of breastfeeding, and describe patterns of breastfeeding and supplemental feeding in the multiethnically and culturally diverse population of Al Ain, UAE. Two-hundred-and-twenty-one infants completed the 4 weeks of follow up. None of the mothers opted not to breastfeed, but only 4 per cent of them practiced exclusive breastfeeding during the first month of the infants' life; 51 per cent of them initiated breastfeeding on the first day of life. Factors associated with delayed initiation of breastfeeding beyond the first day of life included low birth weight, complicated delivery, ignorance of the advantages of colostrum, and young maternal age. Non-milk supplements fed to babies included water, tea, juice, yansun, and babunj (local herbal drinks). The preferred method of feeding the supplements was the feeding bottle. There were significant associations between the use of these supplements and the mother's nationality and education.

Bottle Feeding↗

A study of possible deleterious effects of consanguinity.

The aim of the study was to determine whether consanguineous marriages result in reproductive wastage and an increased incidence of illness in the offspring in a community with a long history of inbreeding and an expected high rate of consanguineous marriage. A representative sample of 2200 women aged > or = 15 years from Dubai and Al Ain, two cities in the United Arab Emirates, representing on the one hand a modern metropolis and on the other a traditional society, were studied. A questionnaire, which included questions on age, parity, gravidity, number of stillbirths, number of abortions, number of children alive, neonatal deaths and specific illnesses in children, was administered by nurses in antenatal and gynaecological clinics in the two cities. The rate of consanguineous marriage was 50.5% and parity, gravidity, ages and number of children were similar in consanguineous and non-consanguineous groups. There was no significant difference in rates of abortion, stillbirth and neonatal death between the two groups. Overall, there was statistically significant higher reproductive wastage in consanguineous couples, but when the category of less than second cousins was excluded from the consanguineous group no difference was found in reproductive wastage between consanguineous and non-consanguineous marriages. Children born to consanguineous unions also had significantly higher incidences of illnesses (37.1%) than those of non-consanguineous unions (29%). The occurrence of malignancies, congenital abnormalities, mental retardation and physical handicap was significantly higher in offspring of consanguineous than non-consanguineous marriages. In conclusion, consanguinity did not result in reproductive wastage, but was found to be an important factor in the causation of specific illnesses in offspring.

Abortion, Spontaneous↗

Pediatric injuries in an Arabian Gulf country.

OBJECTIVE: To determine the common types of injuries among children (0-14 years) in Al-Ain, United Arab Emirates (UAE). DESIGN: A retrospective descriptive hospital based study. SETTING: Al-Ain Medical District, Al-Ain Teaching Hospital, UAE. SUBJECTS: All patients aged 0-14 years seen at Al-Ain Teaching Hospital for injuries during 1994. RESULTS: The number of children with an injury who attended the emergency room was 16,518 (69.9% boys; 30.1% girls). Injury rates were higher among non-UAE nationals. The most frequent reason for hospital admission was poisoning (41%). In the age group < 5 years, the most common causes were falls, blunt trauma, and burns or scalds, while in the 5-9 year and in 10-14 year groups the most frequent cause was road traffic accidents (RTAs). Fights and sporting injuries were also seen frequently in children aged 10-14 years. CONCLUSION: Injury rates were higher in boys and RTAs mostly occurred in children over 10 years. The majority of cases (56%) occurred among non-UAE nationals, who are usually of lower socio-economic status. RECOMMENDATION: Injuries can be prevented by developing strategies to substantially increase the profile of health education to parents and children, by educating policy makers and health professionals, and by environmental modification, legislation, and enforcement. The UAE government can play an important part by establishing and supporting injury prevention programs with these goals.

Accident Prevention↗

Serum IgE level and clinical allergic diseases in the United Arab Emirates.

OBJECTIVE: To determine the serum IgE level in population and its association with allergic diseases in Al-Ain, United Arab Emirates (UAE). DESIGN: This is a prospective descriptive hospital-based study. SETTING: Al-Ain Medical District, Tawam Hospital, United Arab Emirates. SUBJECTS: Patients who were seen at Tawam Hospital for skin, allergic and respiratory diseases during 1996. RESULTS: The study was based on 228 patients. The sample consisted 95 (41.7%) males and 133 (58.3%) females. The mean and standard deviation of age were 25.89 +/- 15.87 years with range 1 and 72 years. The present study revealed that there were no statistically significant differences between serum IgE level and age groups, gender, clinical diagnosis and respiratory symptoms (p > 0.05). Of 59.2% of patients clinically diagnosed were possible IgE related. There was statistically significant differences between serum IgE level and cut (p < 0.030). There was a positive correlation between clinical diagnosis and cut. CONCLUSION: Consistencies and discrepancies between our findings and those from other studies with respect to allergic diseases and IgE level which support the hypothesis that allergic diseases are a multi-factorial diseases related to both familial and environmental influences.

Adolescent↗

Clinical and immunological studies in vitiligo in the United Arab Emirates.

OBJECTIVE: To determine the clinical and immunological changes encountered in patients with vitiligo in Al-Ain population, United Arab Emirates (UAE). DESIGN: This is a prospective descriptive hospital-based study. SETTING: Al-Ain Medical District, Al-Ain Hospital, United Arab Emirates. SUBJECTS: Patients who were seen at Al-Ain hospital for skin diseases during 1996. RESULTS: The study was based on 65 patients. The sample consisted 32 (49%) males and 33 (51%) females. The mean and standard deviation of age for males were 38.6 +/- 13.5 years and for females were 35.1 +/- 15.9 years. Most of the patients were UAE, Omani and Pakistani nationals. Positive family history of vitiligo was found in 19% of the patients. Association with other immune diseases was found in 6% of the patients while one or more organ specific antibodies, all of whom were females, most of them had positive history of autoimmune diseases. CONCLUSION: Vitiligo is more common among UAE nationals since the UAE community including a multi-national society.

Adolescent↗

Factors associated with tuberculin reactivity among children in United Arab Emirates.

A cross-sectional survey of tuberculin skin reactivity was conducted in Al-Ain, United Arab Emirates (U.A.E.) between January and June 1994, to find out the prevalence rate of tuberculosis infection. A pre-designed questionnaire was used to collect details of BCG scar, age, sex, residence area, nationality, education, type of house, number of rooms, family size and household contact history of tuberculosis. A total of 785 students were screened, of whom 547 gave a history of BCG vaccination in the past and 238 were BCG-negative. Among BCG-negative children aged 5-11 years and 12-15 years, only 6.5% and 9.3%, respectively, had a positive Mantoux reaction--a rate lower than most Third World countries, but higher than developed countries where under 2% of children are tuberculin reactors. A general linear model with positive Mantoux reaction as the dependent variable was fitted to the data to examine the joint effect of age, sex, residential area, number of rooms at home, family size and BCG vaccine history. The Mantoux reaction was entered as positive and a number of statistically significant associations were found between positive Mantoux test > 10 mm and: age (P = 0.0018); sex (P = 0.0281); residential area (P < 0.0001); number of rooms (P = 0.0017); and BCG vaccine history (P < 0.0001). However, family size did not have any statistical effect on tuberculin testing (Mantoux test > 10 mm). The prevalence (8%) in the 5-14 years age group puts U.A.E. between low (2%) and middle (14%) prevalence countries, according to the classification of the International Union Against Tuberculosis. This calls for continuation of free treatment of active cases and increased efforts towards screening of contacts.

Adolescent↗

The effect of epilepsy on road traffic accidents and casualties.

A prospective study was carried out between October 1992 and June 1994 to investigate the effect of epilepsy as a risk factor in road traffic accidents (RTA) and casualties in the United Arab Emirates (UAE). The aim of this paper was to investigate the risk and effect of epilepsy on road traffic accidents and casualties and identify possible risk factors for traffic accidents and casualties and identify possible risk factors for traffic accidents and violations among these drivers. Most (70%) were young drivers and under age 40 years; 43% were UAE nationals; 41% had a primary school education; 48.8% had a full license to drive private or commercial taxis; 41% had less than two years driving experience and 17.1% used seat bolts regularly. Most (65.9%) admitted to crossing red traffic lights; 46.3% to parking in forbidden areas; 66% to speeding; 36% to smoking while driving; 34.1% to using the telephone whilst driving; 43.9% to putting their child in the front seat; 20.8% had been previously involved in an RTA; and 53.7% had sustained serious injury. A figure of 34.1% had at least one seizure per year and 26.8% had at least one seizure per month. The most common violations were careless driving (34.1%) and traffic regulation violations (24.4%). Significantly higher risk was observed for property damage (RR = 1.85; 95% CI = 0.64-5.14) and traffic violations (RR-1.91; 95% CI = 0.54-2.29). In the UAE there are no restrictions on the issue of driving licenses to people prone to epileptic seizures. In conclusion, it is emphasized that patients with conditions such as epilepsy should feel obliged to inform the traffic authorities or the health authorities about their condition. It seems likely that the problem could be greatly reduced if appropriate action was taken concerning epileptic drivers. It is hoped that the results and recommendations of this study will be useful to traffic and health authorities.

Accidents, Traffic↗

Sociodemographic risk factors associated with low birthweight in United Arab Emirates.

This case-control study was undertaken to determine sociodemographic risk factors for low birth weight in Al-Ain (United Arab Emirates) over a 12-month period in 1992-93. A total of 3485 live births occurred of which 293 (8.4%) were low birth weight. The risk factors considered were mother's occupation, house conditions, place of residence (urban or rural), maternal smoking habits, antenatal care, availability of help in the home, maternal BMI and educational status. Multiple logistic regression analysis showed that mother's occupation, maternal smoking, antenatal care, and lack of help in the home were associated with increased risk of low birth weight.

Adolescent↗

Neonatal BCG vaccination and tuberculin skin sensitivity among schoolchildren of the United Arab Emirates.

A cross-sectional survey of 785 schoolchildren living in the Al Ain region was undertaken between January and June 1994 to assess the effect of neonatal BCG vaccination on tuberculin sensitivity and to study the risk of exposure to tuberculosis in the same population. A documented history of BCG vaccination was obtained in 547 (69.7%) schoolchildren. The prevalence of a 10 mm or greater induration of tuberculin skin reactivity varied from 8% in unvaccinated to 11.5% among vaccinated children. This was not statistically significant. Children living in urban areas irrespective of vaccination status had a higher rate of tuberculin reactivity than those living in rural areas (relative risk 5.77; 95% confidence interval 1.85-18.00; p < 0.0004). The pattern and rate of tuberculin sensitivity were similar among the other socio-demographic standards investigated. Earlier BCG vaccination had no effect on subsequent tuberculin sensitivity of either negative (0.4 mm), intermediate (5-9 mm) or positive (> or = 10 mm) type skin reactions. It is concluded that the risk of exposure to tuberculous infection is several times higher among children living in urban areas than among those living in a rural environment. Earlier BCG vaccination should not interfere with diagnostic tuberculin skin sensitivity and is still a useful tool in assessing the risk of tuberculous infection in such populations.

Adolescent↗

Genetic and environmental factors associated with asthma.

We investigate the familial and environmental risk factors associated with asthma among United Arab Emirates schoolchildren aged 6-14 years. A cross-sectional study of 850 schoolchildren living in both urban and rural areas (average age 9.36 +/- 2.11 years; 46.8% boys, 53.2% girls) was conducted using self-administered questionnaires between October 1992 and May 1993. The population sample had a high prevalence rate of diagnosed asthma (13.6%) and allergic rhinitis (22.9%). The frequency of asthma, allergic rhinitis, and eczema among parents and siblings reflected the same pattern as that seen in the children. Environmental risk factors associated with asthma were pets, medicine, plants, dust storm, physical exercise, humidity, and perfume. All other factors, such as foods, climate, and parental smoking, showed no apparent relation to the development of asthma. The logistic regression analysis showed that parental asthma, plants, perfume, dust storm, humidity, and pets were the only significant predictors after adjusting for sex and other confounding covariates in the model. In conclusion, risk factors for asthma identified by our study are similar to those found in other community-based studies. Consistencies and discrepancies between our findings and those from other studies with respect to asthma risk factors support the hypothesis that asthma is a multifactorial disease related to both familial and environmental influences.

Adolescent↗