A Bellastella — Page 8

PubMedDate not supplied

Lack of nocturnal prolactin increase in patients with hypogonadotropic hypogonadism.

The circadian prolactin rhythm was studied in a group of 16 male adult volunteers: 10 healthy subjects and 6 patients affected by isolated hypogonadotropic hypogonadism (IHH). A significant nycto-hemeral prolactin rhythm (p = 0.0003, according to cosinor method) is detected in healthy subjects, but not in patients with IHH. In view of these results we may deem that the absence of nycto-hemeral variations of serum prolactin in subjects with IHH could be caused by failure of LH and FSH release.

Adult↗

PubMedDate not supplied

Temporal relationship between circannual levels of luteinizing hormone and testosterone in prepubertal boys with constitutional short stature.

In the present study we refer the results of our researches on LH and testosterone circannual variations in 72 prepubertal boys with constitutional short stature, aged 6 to 10 years. They observed the following life schedule: nocturnal rest from 2200 to 0600, meals at 0800, 1300, 1900. Plasma samples were taken at 0800 and LH and testosterone were measured by RIA. The single independent data were fitted a cosine function to evidence any rhythm and describe its parameters. A significant circannual rhythm in the LH (annual crest time in December) and testosterone (annual crest tine in July) levels was detected, with a phase difference between the two from about 160 degree to 180 degree, i.e. an antiphase. Our data suggest that a temporal relationship may occur between the circannual secretion of LH and testosterone in prepubertal boys.

Body Height↗