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Biomedical subjects

A Bellastella

Publications and source records attributed to A Bellastella.

At least 109 records · Page 6Linked to original sources

[Effect of the degree of short stature on the type of response to tests of pituitary growth hormone reserve].

Two HGH (insulin and L-Dopa) stimulating tests were performed at time interval on 65 subjects with short stature (SDs between -2 and -4.5 according to Tanner) and on 18 control subjects, in order to study the influence of short stature degree on the HGH behaviour during the stimulating tests. The results obtained show that: 1. Statistically the short stature degree does not affect the response to HGH stimulating tests. 2. Two tests are necessary to avoid erroneous diagnosis of dwarfism caused by lack of HGH. 3. No response to HGH stimulating tests in subjects with normal stature may prove a discrepancy between the hormone measured radioimmunologically and its biological action.

Body Height↗

L-Dopa stimulated growth hormone release in the blind.

Following L-Dopa administration (single oral dose of 500 mg), plasma Growth hormone (GH) levels significantly rose in 7 out of 8 normal subjects (aged between 64-83) and in 4 out of 8 blind subjects (aged between 60-88). The mean peak +/- SE in the 8 normal subjects was 24.9 +/- 4.9 ng/ml and in the 8 blind subjects was 11.5 +/- 2.8 ng/ml. These findings represent an additional anomaly in pituitary hormone release in the blind and may indicate that dopamine receptors in the hypothalamus are less sensitive to L-Dopa in blind people than in normal subjects.

Aged↗

Circadian rhythm of plasma cortisol in the aged (Cosinor method).

Plasma cortisol circadian rhythm was investigated in 18 apparently healthy elderly subjects, in 11 elderly patients affected by cerebrovascular hemiplegia and in 11 otherwise healthy blind elderly subjects. Results were microscopically analyzed by the least squares and Cosinor methods. The circadian rhythm of plasma cortisol was present and normal both in elderly subjects and in elderly patients with cerebrovascular hemiplegia. By contrast, a plasma cortisol rhythm was not found in blind elderly subjects.

Aged↗