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Biomedical subjects

A Beigel

Publications and source records attributed to A Beigel.

17 recordsLinked to original sources
PubMed1992

[The magnetic resonance tomographic signs of Wegener's granulomatosis in the head area].

MRI of the head was performed in 25 patients suffering from Wegener's granuloma. 23 patients showed evidence of mucosal thickening in the paranasal sinuses, the middle and inner ears and in the mastoid cells; these were characterised by low signal intensity of T1-weighted and high signal intensity of T2-weighted images. In 10 patients there were granulomas in the paranasal sinuses and in the orbits which showed low signal intensity of both T1-weighted and T2-weighted images. In 4 patients, additional images were obtained after the intravenous injection of Gd-DTPA. In 2 patients this resulted in non-homogeneous contrast accumulation in the granuloma. In 7 patients there were signal changes in the brain which were typical of infarcts. The complete extent of bone destruction in the facial skeleton was visible only by CT.

Adult↗
PubMed1992

[Rhabdomyoma of the mouth floor--a case report].

We report a rare case of an adult rhabdomyoma of the floor of the mouth in a 52-year-old woman. To date only 25 cases of such tumors have been described in the oral cavity. In spite of its large size (approximately 10 x 8 x 6 cm), the tumor could be completely removed. Up to now, 20 months after the removal of tumor, no recurrences, have occurred.

Biomarkers, Tumor↗
PubMed1991

[Immunological reactions against preserved tracheal transplants? Studies on inbred rat strains].

To determine whether chemical (cialit, merthiolate, alcohol, formaldehyde solution) preserved tracheal segments maintain immunogenicity we performed systematic transplantation-immunological investigations using in vivo-, in vitro- and immunohistological tests. In contrast to other authors no indication of residual antigenicity was found. The survival rates after orthotopic grafting of preserved tracheal segments were shortened. This seems due to the loss of the mucociliary clearance, caused by chemical induced damages in the tracheal mucosa.

Animals↗
PubMed1991

[Cefmenoxime penetration in human lacrimal sac mucosa after systemic administration].

Access to microbiological, pharmacokinetic and toxicological information is necessary for useful, controlled application of antibiotics in intraocular and periocular infections. It is important to know whether the antibiotic is effective against ophthalmologically relevant bacteria and if suprathreshold concentrations of the antibiotic can be achieved in the contaminated tissue. In the study presented we investigated the usefulness of cefmenoxime in cases of dacryocystitis. Lacrimal sac tissue--and serum specimens were obtained from 15 patients who underwent dacryocystorhinostomy 0.5 to 13 h after intravenous injection of 25 mg cefmenoxime kg. The usual Toti procedure was performed in 7 patients, whereas the other 8 underwent endonasal surgery. Out of the 15 patients 12 suffered from recurrent dacryocystitis. Before application of the antibiotic a serum control sample was obtained in all patients. The highest cefmenoxime levels in the lacrimal sac (72 mg/kg) were measured 30 min after injection. Thirteen hours after the injection, the cefmenoxime levels were too low to be measured. The levels of cefmenoxime in the lacrimal sac tissue were compared with the minimal inhibitory concentrations for the frequent occurrence of bacteria in lacrimal sac infections.

Adolescent↗
PubMed1990

The seriously mentally ill: another perspective on treatment resistance.

There is a subpopulation of the seriously mentally ill who remain acute care recidivists, rarely becoming engaged in follow-up treatment. It has been argued that these individuals are system, rather than treatment resisters. The perceptions they have of their problems are often in conflict with staff evaluations, or with what the system has to offer. In the present study, patients who dropped out of residential care against staff's advice were compared to patients who remained in treatment. The results suggest that the greater the difference between the perceptions a patient and therapist have concerning the patient's problem, the greater the likelihood of the patient dropping out of treatment.

Adult↗
PubMed1990

[Pathogenesis of alcohol-induced hyperlipidemia: case report of hypertriglyceridemia over 10,000 mg%].

A 53-year old woman developed excessive hypertriglyceridemia (greater than 10,000 mg/dl) with features of toxic liver damage after prolonged ethanol ingestion. Lipoprotein-lipase-activity was not decreased, apolipoprotein-C-II analysis, as shown by gel-electrophoresis, revealed a regular pattern. Treatment with parenteral nutrition and abstinence of ethanol resulted in a complete normalization of plasma triglycerides after transient remnant-hyperlipidemia. Decrease of triglycerides was accompanied by declining liver enzyme activities. As suggested by unimpaired activity of lipolysis, the extent of hypertriglyceridemia may be explained by a reversible receptor mediated defect of hepatic catabolism, aggravated by hepatic overproduction of triglyceride-rich-particles. Although receptor dysfunction is not yet understood, the transient appearance of remnant particles may be a helpful criteria in diagnosis of ethanol induced hypertriglyceridemia.

Alcoholism↗
PubMed1990

[Ultrasound, computerized and nuclear magnetic resonance tomography of soft tissue processes of the head and neck].

14 patients with a space-occupying growth in the head and neck region were examined via sonography, CT and MR to explore and demonstrate by means of a prospective comparative study the possibilities offered by these three imaging methods. Stages are best diagnosed by means of sonography; the leading role of this method is undisputed. To clarify sonographically unclear findings and especially in pre-surgery planning, MR offers advantages over CT on account of the high soft-part contrast and multiplanar visualisation. However, it is impossible or very difficult to differentiate abscesses and lymphadenitides from malignant growths with these three methods solely on the basis of image-morphological criteria.

Abscess↗
PubMed1979

Psychiatric education at the crossroads: issues and future directions.

Psychiatric education is currently facing many critical issues. Their resolution will determine the future availability of psychiatrists and is dependent on the development of new strategies that will require a reorientation in several aspects of current psychiatric education. This may be necessary if the vitality of psychiatry as a specialized branch of medicine is to be maintained and the relevance of psychiatric training and practice to service needs and research objectives is to be increased.

Curriculum↗
PubMed1979

Toward increased psychiatric presence in community mental health centers.

The presence of psychiatrists in community mental health centers has diminished in recent years, especially in centers that are non-hospital-based and that are located in rural or disadvantaged urban settings. The decrease in psychiatric leadership in the centers is particularly notable. Factors contributing to the trend include lower salaries than in the private sector, a decrease in the number of patients with severe mental disorders coming to the centers, and the impact of a decrease in specialized training programs in community psychiatry. The authors suggest several incentives to increase psychiatric presence in the centers, including developing staffing standards as a condition of funding, giving psychiatrists time to do research and evaluation and to teach, and increasing the medical involvement of centers through links with general hospitals, private psychiatric hospitals, and medical schools.

Community Mental Health Centers↗
PubMed1977

Practical issues in developing and operating a halfway house program.

During its six years of operation, the halfway house program of the Southern Arizona Mental Health Center has developed a well-defined set of program goals, referral procedures, staffing patterns, and procedures for operating the houses, many of which are described here. The program serves 25 residents in four adjacent houses. It is operated as a therapeutic community with a broad range of structured activities and treatment modalities and an emphasis on solving reality problems. The staff of director, therapist-counselors, residential (or nighttime) counselors, and volunteer counselors is supplemented by the services of consultants, the mental health center, and community agencies.

Adolescent↗
PubMed1976

The psychiatric resident as an ex-officio community board member.

The authors describe a program in which third-year psychiatric residents participate as ex-officio members on the boards of community service agencies. Experience as board members gives residents a broad understanding of issues related to the delivery of community mental health services and encourages them to continue community involvment after their training is completed.

Attitude of Health Personnel↗
PubMed1975

The psychiatrist-administrator: odd man out?

The development of community psychiatry as a recognized subspecialty of psychiatry and the concomitant growth of community mental health programs have once again brought into focus the role of the psychiatrist-administrator in the practice of public psychiatry. This paper explores the principal conflicts that the psychiatrist-administrator faces in his multiple roles as a physician, psychiatrist, administrator, community services planner, and clinician. Unless he can work toward a resolution of the conflicts and problems that arise, he is in danger of becoming the "odd man out"--the psychiatrist-adminstrator who does not have complete acceptance from any of the groups to which he belongs and within which he is trying to define his combined and complex role.

Administrative Personnel↗