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Biomedical subjects

A Behar

Publications and source records attributed to A Behar.

At least 55 records · Page 3Linked to original sources

Systemic leishmaniasis mimicking malignant histiocytosis.

A 22-year-old man with fever, hepato-splenomegaly and severe pancytopenia is described in whom the histologic features of the spleen, liver and lymph nodes were consistent with malignant histiocytosis. Characteristic Leishman-Donovan bodies were demonstrated on a bone marrow aspirate, and the diagnosis of visceral leishmaniasis was confirmed by culturing the flagellated forms of the pathogen, and by an excellent response to sodium stibogluconate. In view of the similarity in clinical and histologic appearance, visceral leishmaniasis must be considered in the differential diagnosis of malignant histiocytosis in geographic areas where leishmaniasis is still endemic.

Adult↗

[Study of muscle hemodynamics during exercise: Physiological and pathological variations in Xe 133 elimination: A new method of interpretation (author's transl)].

Muscle blood flow measurements are of physiological (and pathological) significance only during effort. For this reason, the authors used Xe 133, which has been known since 1964, to measure regional muscle blood flow after its injection into the muscle, to quantify results during effort (pedalling). Effort is controlled by two measurable parameters: the weight lifted by the pedal and the frequency of movements. Curves showing the reduction in intramuscular Xe 133 levels cannot be mathematically formulated. It is easy, however, to measure their areas and thus define a mean elimination time (Tm) between times T1 and T2, beginning and end of effort, corresponding to activities A1 and A2 such that: formula: (see text). Normal Tm value, measured in 58 normal subjects with variable frequencies and weights lifted is: Tm = 1.70 +/- 0.38 min. The values in 70 patients with arteritis were significantly longer and can be greater than 3.5 min. This objective test could be of value in quintifying the effects of so-called vasodilators, both in patients with arteritis and venous insufficiency.

Humans↗

Teratoid intraocular medulloepithelioma.

The right eye of a 1-year-old black infant with a painful blind eye was studied histologically. It contained a tumor at an advanced stage of growth. The tumor consisted of moderately large, round, and elongated undifferentiated cells and anaplastic cells with mitotic figures combined with multilayered, poorly differentiated epithelial cells that resembled the medullary epithelium of embryonic retina. Strap cells with cross striation typical of striated muscle were also present, together with islands of hyaline cartilage and areas of calcification.

Ciliary Body↗

Ultrastructure of hepatocellular carcinoma in a cirrhotic liver.

Hepatoma cells, though sharing many similarities with non-neoplastic hepatocytes, showed conspicuous alterations--increased nuclear/cytoplasmic ratio, intranuclear invapinations of cytoplasm, lipoid material, high mitotic activity, and the presence of abundant small fat droplets and glycogen in the cytoplasm. "Capillarization" of sinusoids was a constant feature with the appearance of junctions between endothelial cells, deposition of fibrillary material in Disse's spaces, flattening of hepatocyte microvilli and deposition of basement-membrane-like material. Abundant microtubules and the presence of annulate lamellae were other features noted in the tumor cells.

Adult↗