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Biomedical subjects

A Bauman

Publications and source records attributed to A Bauman.

At least 109 records · Page 6Linked to original sources
PubMed1994

226Ra in drinking water in the Republic of Croatia.

Owing to its exceptional radiotoxicity 226Ra in drinking water may directly affect human health. Its presence was investigated in several categories of drinking water in Croatia: well water, tap water from several municipal water supply systems and bottled mineral water. The method of 226Ra determination was alpha-spectrometric measurement after radiochemical separation. The 226Ra content in all investigated categories of waters are below the legislative level permissible for human health.

Croatia↗
PubMed1994

Utilisation rates of primary care services in an emergency department.

Rates of patients attending for primary care reasons at the emergency department of Campbelltown Hospital were estimated to identify trends in utilisation, reasons for attendance and social characteristics. The proportion of 'primary care' patients attending the emergency department is increasing. The reasons for the increase are not known and require further investigation.

Adolescent↗
PubMed1993

Ligand-protein electrostatic interactions govern the specificity of retinol- and fatty acid-binding proteins.

Cellular retinol-binding protein II (CRBP-II) and intestinal fatty acid-binding protein (I-FABP) are both expressed in small intestinal enterocytes and exhibit 31% sequence identity. I-FABP binds a single molecule of long-chain fatty acid and forms an ion-pair electrostatic interaction between the cationic side chain of arginine-106 and the anionic fatty acid carboxyl group. In contrast, CRBP-II binds all-trans-retinol or -retinal and contains a glutamine residue in the corresponding position, residue 109. We have characterized and compared the interactions of fatty acids and retinoids with I-FABP, CRBP-II, and two reciprocal mutant proteins. The mutants were designated CRBP-II(Q109R), where glutamine-109 was replaced by arginine, and I-FABP(R106Q), where arginine-106 was replaced by glutamine. As monitored by titration calorimetry and carbon-13 NMR spectroscopy, the fatty acid-binding properties of CRBP-II(Q109R) were found to be essentially identical to those of wild-type I-FABP. Both proteins bound 1 molecule of fatty acid with identical affinities (Kd = 0.2 microM). The enthalpic contribution to the total free energy of binding was large for both proteins: 66% and 87%, respectively. In addition, the carboxyl groups of fatty acids bound to both proteins were solvent-inaccessible. There was little or no change in the ionization state of the bound fatty acid over a wide pH range, as monitored by the chemical shift of the fatty acid carboxyl 13C resonance. Furthermore, the binding of fatty acid to both proteins was accompanied by a selective perturbation of the guanidino 13C resonance of a single arginine residue.(ABSTRACT TRUNCATED AT 250 WORDS)

Animals↗
PubMed1993

The impact of a mass communications campaign on the reported management of asthma by general practitioners.

There have been recent campaigns in many countries to address the increasing morbidity and mortality of asthma by promoting better management. This study aimed to evaluate the National Asthma Campaign (NAC), in Australia, and to assess the extent of its impact on reported asthma management. It was a cross-sectional, before and after study using the same self-administered questionnaire in postal surveys involving 472 general practitioners (GPs) before the campaign and 540 GPs 6 months after the start of the campaign. Both samples were random samples of GPs in active practice. The campaign was effective in making GPs more aware of the principles of good asthma management. Most (74%) GPs in the post-campaign survey were aware of a current asthma education programme compared with 53% in the pre-campaign survey, although only 23% cited the NAC. After the campaign there were significant improvements reported in airway function measurement practices, the use of preventive therapy and the use of written action plans.

Asthma↗
PubMed1993

Radioactive contamination of the Adriatic Sea by 90Sr and 137Cs.

Results of systematic long-term measurements of 90Sr and 137Cs in surface seawater, performed at four locations along the Croatian coast of the Adriatic Sea, are summarized. Observed trends in annual mean activity concentrations are discussed. 90Sr and 137Cs fallout activities affect seawater activity, the coefficient of correlation between 90Sr fallout activity and 90Sr seawater activity being 0.72. No significant variations of 90Sr mean residence time in the sea-mixed layer on different locations were found. From 1978-1985, the 137Cs:90Sr activity ratio in seawater was 1.52 +/- 0.40. In May 1986, as the consequence of the Chernobyl nuclear accident, this radio increased to 92.4 +/- 58.2.

Accidents↗
PubMed1993

Warning! Schools can damage your health: alienation from school and its impact on health behaviour.

An international study of health behaviour among school-age children was co-ordinated by the World Health Organization (WHO). The data were obtained from a self-completion questionnaire examining key health behaviours and associated psycho-social variables obtained from representative samples of young people in school aged 11.5, 13.5, and 15.5 years. The analysis focuses on the relationship between older (15.5 years) students' attitudes towards school and health behaviours such as regular smoking, alcohol use, physical activity and food choices. The data show a strong and progressive relationship between indicators of 'alienation' from school, and health compromising behaviours among school students from Australia and Wales. This relationship is most obvious with the 'abusive' behaviours of smoking and alcohol misuse. Summary data for nine other countries in the WHO study indicate that this relationship is found consistently across all countries in the study. This substantial minority of students (approximately 30% varying between countries) represents an important target population for efforts to promote healthy lifestyles. Traditional school health education is seen as insufficient to tackle this task and recommendations are made concerning change to the school environment and ethos, and the need to reach young people in their home and community settings.

Adolescent↗
PubMed1993

Has the prevalence of asthma symptoms increased in Australian children?

This paper estimates whether an increase has occurred in the prevalence of asthma symptoms and diagnosed asthma in Australian children over the past two decades. Seventeen population-based studies undertaken in Australia since 1969 were reviewed. Inclusion criteria were studies using population samples of children aged 5-12 years, with standardized questionnaire measurements. Data from serial National Health Surveys were also examined for trends in recent and chronic asthma. The prevalence of recent (12 month) and cumulative wheeze increased, showing a significant correlation with year of study (r = 0.78 and r = 0.79, respectively). Diagnosed asthma showed a smaller but still significant increase (r = 0.65). The trends observed indicated that diagnosed asthma and reported wheeze have increased by almost 1% per year over the past two decades. Data since 1980 have provided estimates of bronchial hyperreactivity (BHR), but no trend was observed. Substantial increases were noted in the National Health Surveys, with recent asthma prevalence in children aged 5-14 increasing from 3.3% in 1983 to 8.3% in 1989, and chronic asthma prevalence increasing from 4.5% in 1977 to 15.2% in 1989. The findings of this review suggest an increase in the prevalence of asthma symptoms in children, but these observations could also be explained by changes in diagnostic fashion and an increased awareness of asthma symptoms.

Asthma↗
PubMed1993

Controlled trial evaluation of an asthma education programme for adults.

BACKGROUND: To improve asthma control and reduce readmission rates through increased knowledge and the development of self management skills, a brief (three hour) adult education programme was developed. METHODS: The course was designed to improve inhaler skills and to teach how to adjust drug doses according to peak flow (PEF) measurements and a treatment plan. It was evaluated in a randomised controlled trial in 76 patients admitted to hospital for asthma by using questionnaires, spirometry, and home monitoring of PEF at entry and at five and 10 months after intervention. The questionnaire provided measures of knowledge about asthma, self management behaviour appropriate to asthma control, asthma symptom frequency and severity, and psychosocial disturbance attributable to asthma. RESULTS: During the 10 months observation period the readmission rate for the educated group was one seventh that of the control group and attendance at accident and emergency departments also decreased. No consistent differential improvements were observed in spirometric results, average PEF, or mean daily variability of PEF. Both groups showed improvements in measures of asthma knowledge, behaviour, symptoms, and psychosocial disturbances. However, the intervention group showed a significantly greater improvement in some measures of asthma knowledge and self management skills. CONCLUSION: Despite minimal effect on measures of airway function, substantial changes in illness behaviour and use of health care facilities can be achieved by a brief asthma education programme.

Adolescent↗
PubMed1993

Population prevalence and correlates of stages of change in physical activity.

Stages of change for exercise, sociodemographic variables, and beliefs about the health benefits of exercise were obtained for a representative sample of Australian adults (N = 4404). Logistic regression analysis was used to examine the relationship between exercise stage of change and sociodemographic variables and beliefs about the benefits of exercise. Thirteen percent of respondents stated that they did not exercise and did not intend to start; 10% stated that they did not exercise but were thinking of starting; 16% stated that they exercise occasionally and were not thinking of doing more; 23% stated that they exercised occasionally and were thinking of doing more; and 38% stated that they exercised regularly and intended to continue. Intention to do more exercise generally decreased with increasing age, but increased with level of education. An increased frequency of exercise and an intention to do more exercise was associated with the belief that exercise would help to prevent heart disease and with a higher level of education. The results provide a useful profile of the exercise habits (and intention to change those habits) of population subgroups. Public communication campaigns on the benefits of physical activity should focus particularly on those who do not intend to exercise, older adults, and the less well educated.

Adolescent↗
PubMed1993

Self-reported prevalence of asthma symptoms in children in Australia, England, Germany and New Zealand: an international comparison using the ISAAC protocol.

There is a need for a standardized approach to international and regional comparisons of the prevalence and severity of asthma, and for the monitoring of asthma morbidity over time. In 1991, standardized written and video questionnaires were developed and administered in surveys of schoolchildren, aged 12-15 yrs, in five regions in four countries: Adelaide, Australia (n = 1,428); Sydney, Australia (n = 1519); West Sussex, England (n = 2,097); Bochum, Germany (n = 1928); and Wellington, New Zealand (n = 1863). The self-reported prevalence of wheezing during the previous 12 months was similar in West Sussex (29% using the written questionnaire and 30% using the video questionnaire), Wellington (28 and 36%), Adelaide (29 and 37%), and Sydney (30 and 40%), but was lower in Bochum (20 and 27%). The one year prevalence of severe wheezing limiting speech was greater in Wellington (11%), Adelaide (10%) and Sydney (13%), than in West Sussex (7%) and Bochum (6%). The self-reported one year prevalences of frequent attacks, frequent nocturnal wheezing, and doctor diagnosed asthma, were also higher in the Australasian centres than in the European centres. We conclude, that an international comparison of asthma symptom prevalence in childhood, using simple standardized instruments, is feasible. Possible explanations for the differences in reported asthma severity between the Australasian and European centres include differences in exposure to risk factors and differences in the management of asthma.

Adolescent↗
PubMed1993

[Protection of the Croatian population from accidental radioactive contamination of the food chain].

The paper indicates the importance of investigating radionuclide translocation in the human food chain, and the contribution of selected food components in total exposure of the population after accidental radioactive contamination. Data on radioactive contamination and risk assessment of the Croatian population after the Chernobyl nuclear accident are given and possibilities of decontamination of food chain components are discussed. Literature data on radionuclide removal from the human food chain are compared to the results of own investigations. Emphasis is placed on biologically most important radionuclides, 131I, 90Sr, 137Cs, and the most effective means of protection are sought. The preventive measures following a nuclear accident should be based on the cost-benefit principle i.e. the damage from applying radiation protection measures should not exceed the benefit from possible dose reduction.

Accidents↗
PubMed1993

Asthma in general practice. Opportunities for recognition and management.

OBJECTIVE: To describe the prevalence of asthma-related symptoms and asthma among patients attending general practitioners. SETTING: Sydney. DESIGN: Cross-sectional survey by written questionnaire. SAMPLE: 1933 patients of 21 general practitioners. RESULTS: 1. Wheeze and asthma were common in patients attending general practitioners; 19 per cent of patients reported recent wheeze, 9 per cent reported recent asthma. 2. Less than half of all patients with recent wheeze (47%) reported having asthma. 3. Recent wheeze without asthma was more common in boys (4.8%) than girls (0%) and more common in men (10%) than women (7%). 4. Although most patients reporting asthma (95%) had had their asthma treated by a doctor, three-quarters of those patients had experienced asthma related symptoms in the previous year. CONCLUSION: Asthma remains under-recognised and under-treated among patients attending general practitioners.

Adolescent↗
PubMed1992

Improved care of patients with diabetes through telecommunications.

This project tested the importance of enhanced information transfer of home monitoring results to health care providers. The study tested whether computer-assisted communication of medical information between the chronic care patient and the physician can result in health care benefit. The information tools were constructed/adapted as a test of this hypothesis for diabetes mellitus. Patients connected a glucometer to an intelligent modem weekly for six to nine months. Graphical and mathematical tools extracted and emphasized the information content of the home monitoring data arriving at the central site. Data smoothing, trend analysis, and calculation of quality control statistics were incorporated into a graphical time series oriented report that was used by the health care provider during an outpatient visit. The integrated home monitoring system was tested on 20 patients with diabetes in a double cross-over design over a 15-month period. A significant improvement in serum glucose control as measured by glycated hemoglobin was shown in the study group, but not in the control group.

Algorithms↗
PubMed1992

Asthma morbidity in Australia: an epidemiological study.

OBJECTIVE: To examine the prevalence and management of asthma in adults and children in a population sample in eastern Australia. SETTING: A random sample of children from 33 primary schools in Sydney, Melbourne, Brisbane, and the Upper Hunter Valley (New South Wales), and their parents. DESIGN: A cross-sectional analytic survey of 8753 primary school children aged between 5 and 12 years, and their parents (n = 13,945 adults). Asthma prevalence and management practices were determined by parental responses to a questionnaire, and spirometry was performed in children with "probable asthma". RESULTS: Of 8753 children whose parents responded, the prevalence of current wheeze was 19.5% and diagnosed asthma was 17.1%. Of the children with "probable asthma", 30% had their lung function measured in the previous year, and 6% possessed both a peak flow meter and an action plan for their asthma. Undertreatment was likely, as preventive asthma medications (inhaled corticosteroids or sodium cromoglycate) were used regularly by only 25.5% of these children and by 44.3% of children who had asthma symptoms more than twice per week. Children with the diagnosis of asthma reported higher rates of preventive medication use and ventilatory function measurement than children with frequent symptoms without the diagnosis. In the 13,945 adults, the reported prevalence of asthma was 7%, of whom 39% were using preventive medications, 34% had their ventilatory function assessed in the previous year, and 7% had both a peak flow meter and an asthma action plan. CONCLUSIONS: The study illustrated the gap between the current level of asthma management in the community and the standards set by the Thoracic Society of Australia and New Zealand. Undertreatment and suboptimal management of asthma remain important problems in Australia.

Administration, Inhalation↗
PubMed1992

Asthma prevalence and management in Australian adolescents: results from three community surveys.

Three population surveys of asthma, conducted as part of a community-based asthma education program in southwestern Sydney, Australia, illustrate the relationship between health behaviors and asthma morbidity. The first survey was carried out in five secondary schools (n = 2514, 52% participation rate); the second survey, in eight schools (n = 4550, 82% participation rate); and, the third survey was conducted among patients who attended 38 general practices in the region (n = 633 adolescents, 72% participation rate). The prevalence of diagnosed asthma in Australian adolescents across all three studies was 16.5% (95% CI, 15.7%-17.3%). Asthma prevalence declined in males, but increased in females from ages 12-15 years. It was noted that smoking prevalence was similar in asthmatic adolescents, compared with nonasthmatics, and that the adoption of smoking occurred at similar ages. Further, behavioral self-management of asthma was infrequent in this group, with low levels of preventive practice and preventive medication use. We present a conceptual model of the barriers to optimal asthma management among asthmatic adolescents. The results of these surveys have led to community-wide efforts to improve asthma management and decrease smoking prevalence among these adolescents.

Adolescent↗
PubMed1992

The descriptive epidemiology of a sedentary lifestyle in adult Australians.

Regular exercise is important for the maintenance of good health, but many people do very little exercise. There are public health concerns about activating the sedentary and, from an epidemiological measurement perspective, there are advantages in assessing physical inactivity. Using pooled data from 17,053 participants in Australian population surveys, we identified 5078 people (29.7%) who could be classified as sedentary in their recreational exercise habits. Logistic regression analyses found the inactive to be more likely to be older, less well educated, and to have lower incomes. The main reasons given for not exercising were no time (33%), being physically unable (23%), and not wanting to exercise (13%): these were more likely to be reported by those who were older, and who had lower incomes; the only exception was that being 55 years or older was not associated with having less time. Women were more likely to report being physically unable to exercise. Lower income was associated with being physically unable, and with not wanting to exercise. Those with children, while wanting to exercise, were more likely to report having no time. The greatest health benefits will result from the sedentary becoming more active, and inexpensive and convenient activities such as walking need to be emphasized.

Adult↗
PubMed1992

Risk estimation of radioactive contamination after the Chernobyl accident using bioindicators.

After the Chernobyl nuclear accident, game meat and, in particular, sheep meat in the Republic of Croatia showed a high degree of radioactive contamination compared to large livestock. The activity concentrations of 131I, 134Cs, and 137Cs were measured in meat and internal organs (i.e., lung, liver, kidney, and heart) of game (e.g., venison, hare, and wild boar) and sheep that were used as biological indicators of radioactive contamination. In order to estimate the importance of game and sheep as a dietary source of radioactivity, the effective dose equivalent for the average and critical population (hunters and livestock raising families) were calculated. The data indicated that sheep meat represents greater risk for the human population, in case of a nuclear accident, than game meat. The share of meat from sheep (4.4%) prevailed over the share of meat from game (0.5%) when comparing the average intake of meat per inhabitant in Croatia. This result pointed to an increased risk for families who depend mostly on sheep meat in the case of a nuclear accident.

Accidents↗