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Biomedical subjects

A Basile

Publications and source records attributed to A Basile.

72 records · Page 4Linked to original sources
PubMedDate not supplied

A comparison of pneumogram recordings in infants in the hospital and at home.

It is not known how environment affects the ventilatory pattern of infants during sleep. Pneumogram recordings of ventilatory pattern and electrocardiograms are performed both in the hospital and at home. However, it is not known if the data obtained in these two settings are comparable. Therefore, 12-hour overnight PNGs were recorded in the hospital and at home within 10 days on 64 infants in three diagnostic categories: apnea of infancy, apnea of prematurity, and siblings of victims of sudden infant death syndrome. Pneumograms were quantitated for total sleep time (TST in minutes), longest apnea (in seconds), periodic breathing, and the total duration of apneas lasting 6 seconds or longer. TST was longer at home for the total group (p less than 0.001) and for the apnea of infancy group (p less than 0.005). No other differences were found between hospital and home recordings for any parameter. There was no difference in the number of abnormal pneumograms recorded in the hospital and at home. Therefore, hospital and home pneumogram recordings are equally sensitive and accurate.

Electrocardiography↗
PubMedDate not supplied

Experimental inoculation of avian polyomavirus in chemically and virally immunosuppressed chickens.

The purpose of this series of experiments was to determine the effect of various types of immunosuppressive treatments (cyclophosphamide, infectious bursal disease virus [IBDV], chicken anemia virus [CAV], and combination infection with IBDV and CAV) on susceptibility of chickens to challenge with avian polyomavirus. In the first experiment, chickens were chemically bursectomized with intraperitoneal injections of cyclophosphamide; in the second study, chickens were orally inoculated with IBDV; in the third study, birds were intramuscularly inoculated with CAV; and in the final study, birds were inoculated with both IBDV and CAV. In all experiments, chickens were challenged with 10(4.7) tissue culture infective doses of polyomavirus intraperitoneally. Only chemically bursectomized chickens developed lesions similar to those found in the naturally occurring multisystemic fatal form of polyomavirus infection seen in psittacine nestlings, including hepatic necrosis and large pale intranuclear inclusions.

Animals↗
PubMedDate not supplied

[Endovascular repair of abdominal aortic aneurysm: helical CT findings].

Endovascular repair of infrarenal abdominal aortic aneurysms is currently widely diffuse. Imaging plays a major role in the preprocedural patient evaluation, implantation of stent-graft, and patient follow-up. The aim of this paper is to describe the more frequent findings that can be seen in CT examinations after endovascular repair of infrarenal abdominal aortic aneurysm. We discuss CT findings related to the aneurysm (size, exclusion with complete perigraft thrombosis, back-filling of aneurysm sac via branch vessels) and to the device (dislocation, rotation, kinking, device expansion, patency/thrombosis, device disruption). We also show some examples of incorrect assembly of the modular components of the stent-graft.

Aortic Aneurysm, Abdominal↗
PubMedDate not supplied

[Is appearance of bronchiolitis affected by environmental and genetic factors?].

We have respectively studied 39 patients (22 males and 17 females) in an age below 18 months affected with bronchiolitis and hospitalized in the "Istituto di Pediatria B (Institute of Pediatrics B) of Palermo's University from november 1986 to april 1987. The parameters we have considered are: 1) the family predisposition to atopy; 2) the type of suckling; 3) the social and economical conditions pointed out the overcrowding index; 4) the every day consumption of cigarettes by the cohabitant relatives; 5) the total dosage of IgE. The data of the hospitalized patients have been compared with the ones pointed out in an "examination group" formed by 64 subjects (36 males and 28 females). The frequency of family predisposition to atopy in our patients has turned out to be inferior to the group examined. The overcrowding index allowed a superposition in the two groups. Among our patients we have found a smaller amount of breast-fed babies and a greater number of smoking cohabitant in comparison with the controls even if the differences statistically were not significant. The serial IgE levels, carried out in 29 patients, resulted high in 6 children (20.69%).

Age Factors↗
PubMedDate not supplied

[Recurrent wheezing in subjects with preceding bronchiolitis. Role of environmental and genetic factors].

We have been following for one year 39 patients, who had been hospitalized in our Institute for an episode of bronchiolitis in the period between November 1986 and April 1987. Only 30 patients (17 males and 13 females) have completed the follow up. The patients have been divided into two groups. The group A (subsequent episodes of broncho-stenosis) was made up of 14 subjects, where as the group B (not-subsequent episodes of broncho-stenosis) counted 16 subjects. In the first group the episodes of wheezing have been 3,14 for Year (range 1-6). The patients of the two groups didn't differ for the gestational age, birth weight, respiratory distress in the first life hours; they moreover were homogeneous for the clinical gravity score and for the period in bed. We have evaluated if certain environmental factors such as the passive smoking, the socio-economical and dwelling conditions of the family and some genetic features such as the familiarity for atopy and the Ig E level may predispose the patients affected by bronchiolitis to a higher incidence of recurrent wheezing. Our data show how the above mentioned factors do not influence the recurrent wheezing in the patients with preceding bronchiolitis.

Bronchiolitis↗
PubMedDate not supplied

[Urinary tract infections in the first 2 years of life. Usefulness of anamnesis in the identification of at risk subjects with malformation uropathies].

We have retrospectively studied 101 patients with an age below 24 months consecutively hospitalized, for symptomatic urinary tract infections, in the "Ospedale dei Bambini" of Palermo and subjected to radiological studies (urography and voiding cystouretrography). We have considered if the symptoms and the clinical objectivity could have given useful indications in the choice of the patients to be subjected to radiological studies. The clinical-anamnestic data have not allowed to distinguish, among patients with U.T.I., between the individuals with an abnormal conformation those with a normal one; however they have allowed to focus our attention on patients with U.T.I. through the singling out of some symptoms such as fever, vomit, cyanosis and anomaly micturition. Another datum standing out from our study is that the beginning of the symptoms in patients with U.T.I. was more precocious if at their basis there was urinary malformation.

Age Factors↗
PubMedDate not supplied

[Axillofemoral bypass: a potential solution of acute ischemia of the lower limb].

When deobstruction by Fogarty catheter fails, the axillofemoral bypass can be considered as a therapeutic solution of the acute ischaemia of the limb. The authors discuss a case occurred in their experience and focus their attention on the therapeutic potentiality of this kind of revascularization. As a matter of fact it is important to consider that the operation should not only eliminate the acute ischaemia, but also correct the atherosclerotic lesions that led to it. Therefore, if deobstruction by Fogarty catheter does not restore a good inflow, in high risk patients with acute arterial thrombosis of the limb, there is a well indication for extra-anatomic revascularization.

Acute Disease↗
PubMedDate not supplied

Enzymatic hydrolysis of DNA using a membrane bioreactor.

Aim of this work was a kinetic study of the deoxyribonuclease I (E.C. 3.1.21.1.) reaction in several conditions. Optimal reaction conditions with enzyme free in solution were determined. DNase activity was studied as function of several parameters such as pH, enzyme concentration, substrate concentration, cofactor concentration. The Km value of the free enzyme was also determined. Subsequently, the possibility to carry out the reaction in systems in which the enzyme was immobilized on the inner surface of the polymeric membranes was evaluated and realized. Experimental procedures, in these new conditions, permitted to determine the mass of immobilized enzyme and the percentage of the reaction product recovery. Results showed that the immobilization procedure determines a decay of the initial activity of enzyme, but there is an important increase of enzyme stability.

Animals↗