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Biomedical subjects

A Baran

Publications and source records attributed to A Baran.

At least 19 recordsLinked to original sources
PubMed2003

Sarcoidosis after use of interferon for chronic hepatitis C: report of a case and review of the literature.

Although interferon has not been classified in the pathogenesis of sarcoidosis, it may rarely lead to this disease during treatment of chronic hepatitis C. The case of a 36-year-old woman with chronic hepatitis C who developed sarcoidosis within 10 weeks of treatment with recombinant interferon-alpha2a and ribavirin is described and all seven similar cases published in English from 1989 to 2001 are discussed.

Adult↗
PubMed2001

Composted grape marc as growing medium for hypostases (Hypostases phyllostagya).

The use of composted grape marc (CGM) as a plant growth medium was investigated with Hypostases (Hypostases phyllostagya). Seven media were prepared using CGM mixed, in different ratios, with native peat and perlite. The following mixtures were used: 100% CGM, 75% CGM + 25% peat, 50% CGM + 50% perlite, 25% CGM + 75% peat, 50% CGM + 25%) peat + 25% perlite, 25%, CGM + 50%, peat + 25% perlite and 100% peat. The experiment was arranged in a randomized plot design with four replicates under greenhouse conditions. After a growing period of three months, some horticultural parameters were measured. Besides, some physical and chemical properties of the growing medium were determined. The mixtures of 50% CGM + 50% peat, 25% CGM + 75% peat and 100% peat were found to be most suitable based on the horticultural parameters. This was confirmed through the physical characteristics. Up to 50% composted grape marc can be used in mixtures with peat on account of its low cost and high nutrient content.

Botany↗
PubMed2001

Delays in the diagnosis and treatment of hospitalized patients with smear-positive pulmonary tuberculosis.

The aim of present study was to investigate whether there was any delay in the diagnosis and treatment of inpatients with smear-positive pulmonary tuberculosis followed-up in our centre. We reviewed clinical records in February 1999 and identified 134 hospitalized patients with smear-positive pulmonary tuberculosis. Clinical files of the patients were analysed and a questionnaire was completed. Several intervals and delays were calculated. Median application interval was 17.5 days [95% confidence interval (CI) 21.3-32.4 days], median referral interval was 3.5 days (95% CI 6.8-11.4 days), median diagnosis interval was 3 days (95% CI 3.3-4.5 days) and median initiation of treatment interval was 1 day (95% CI 1.1-1.6 days). Patients delay was present in 28.4% of cases. The referral interval was longer than 2 days in 82 patients (institutional delay). Ninety-three patients (69.4%) had delays in the diagnosis and 34 patients (25.4%) had delays in the treatment. There was a doctor's delay in 119 of 134 patients (88.8%) and clinic's delay in 98 patients (73.2%). Our results have suggested that hospitalized patients with smear-positive pulmonary tuberculosis experience several delays. These delays may result in increased risk for transmission of infection. Decrease in the risk of infection for community and medical personal may only be obtained by preventing these delays.

Adolescent↗
PubMed1998

Opposite trends of changes in reactive behaviours of macrophages and astrocytes following gamma-irradiation performed at different stages of prenatal development. A study in the injured brain of 6-day-old rat.

Pregnant Wistar rats were exposed to a single 1.0 Gy dose of gamma rays on gestational days 13, 15, 17 or 19 (E13s, E15s, E17s and E19s, respectively). A mechanical injury was made in the cerebral hemisphere of their 6 day-old male offsprings. The injured rats were injected with [3H] thymidine on day 1 or 2 after injury and killed 4 h after the injection. Brain sections were processed for BSI-B4 isolectin histochemistry, subjected to autoradiography and examined microscopically to record numbers of proliferating and unproliferating macrophages located within the region of injury. The total number of macrophages as well as number of their divisions were minimal in E13s then showed a regular increase in E15s and E17s, and reached its maximal level in brains irradiated on E19. The trend of changes was opposite to that showed by changes in the intensity of astrocyte proliferation [Z. Setkowicz, K. Janeczko, Effects of prenatal gamma-irradiation on the astrocyte proliferation in response to injury in the brain of 6-day-old rat, Brain Res. 803 (1998) 122-128.]. The recruitment and proliferation of macrophages and the astrocyte proliferation were regarded as reactive processes occurring under control of different regulatory mechanisms acting within the region of injury.

Analysis of Variance↗
PubMed1993

Mortality in Poland in the period 1950-1990.

"In this paper, crude, specific [mortality] rates as well as nonstandardized and standardized indices of regional mortality differentials are analysed [for Poland] for the period 1950-1990, in order to show mortality differentiation, its increase by age, sex, and place of residence. Taking into account cause specific death rates, the pattern of causes of deaths was found to be similar to that existing in the western countries, although the level of standardized mortality is higher in Poland. Values of calculated indices of regional mortality differentials point to significant differences in mortality by voivodship."

Age Factors↗
PubMed1992

[Mortality in the years 1950-1990].

"The author of the paper has attempted to show...trends in...mortality by sex, age, place of residence and [the] selected most important death causes in Poland. The crude and the specific as well as standardized death rates and life expectancy have been analyzed for the period...1950-1990." (SUMMARY IN ENG)

Age Factors↗
PubMed1992

[Diagnostic value of planar perfusion scintigraphy of the heart using Technetium Tc 99m with methoxy-isobutylisonitrile (MIBI)].

99mTc-MIBI (2 methoxy -isobutylisonitrile) belongs to the new generation of radiopharmaceuticals used for studies of myocardial perfusion. Particularly convenient characteristics of the compound prompted numerous studies of its usefulness for scintigraphic diagnostics of coronary artery disease and myocardial heart infarct (detection, localization, size). In the present paper the diagnostic utility of planar heart scintigraphy with 99mTc MIBI is assessed, the compound had been prepared in the Department of Nuclear Medicine, Medical University of Lódź. The scope of the study included detection of stress induced ischaemia and of permanent perfusion defects, treated as post infarct scars in myocardium. The study was made on 109 patients (78 males, 31 females; age 32-68 years). The first group comprised 56 patients with suspected or diagnosed coronary artery disease, however, without history of previous heart infarct. Results of stress and rest scintigraphy were juxtaposed with those of coronarography, which served as a reference method. In 25 patients the latter revealed critical (greater than 70%) stricture of 1 or 2 coronary arteries. In 31 patients of this group the vessels were either of normal appearance or only marginally stricture. Sensitivity, specificity and accuracy of the scintigraphy in diagnosis of ischaemia due to critical narrowing of coronary arteries amounted to 80, 84 and 82 per cent, respectively. Localisation of perfusion defects was adequate in 20 out of 31 vessels (64 per cent). The second group of patients included 53 individuals with previous heart infarct (25 and 11 had a transmural and nontransmural infarct of the anterior wall, respectively; in 12 and 5 a transmural and nontransmural infarct of the inferior wall was diagnosed, accordingly).(ABSTRACT TRUNCATED AT 250 WORDS)

Adult↗
PubMed1991

Population changes and the cost of health care for the elderly in Poland.

"The author...has attempted to measure the effects of population changes upon the costs of health care [in Poland] by applying a simulation model. In this model the total cost of health care is a function of the per capita cost of health care by age, sex, and place of residence (urban, rural) and population structure.... The paper includes...the results concerning population 60 years of age and over." Data are from several official health-related surveys carried out in 1989.

Adult↗
PubMed1980

Evaluating patients' warfarin requirements.

Seventy consecutive patients receiving warfarin as an anticoagulant were evaluated for the relationship between the response to the loading dose of warfarin and the response to the maintenance dose. No patients were excluded because of complicating diseases or the concurrent use of other drugs. There was a moderate correlation (r = 0.54, p less than 0.01) between response to the loading dose and response to the maintenance dose. Thus, a relatively weak response to a loading dose of warfarin can be used to predict a need for a relatively large maintenance dose in unselected patients requiring anticoagulant therapy. Age seems to be a relatively weak determinant of warfarin sensitivity. Other factors such as the genetic control mechanism, concurrent drug therapy, and complicating diseases apparently are more important determinants.

Adult↗
PubMed1978

Birth parents who relinquished babies for adoption revisited.

The fact that adoption records may be opened by court decree to enable adoptees to have access to identifying information about their birth parents makes it incumbent upon those concerned with adoption practices to study the impact of this on adoptees, adoptive parents, birth parents, and professional practice. This paper reports on research addressed to the attitudes and feelings of birth parents years after they relinquished babies for adoption.

Adoption↗
PubMed1976

The effects of the sealed record in adoption.

The authors found that 40 of 50 adult adoptees who had reunions with their birth parents found the experience satisfying. Only 10% of the birth parents reacted adversely, although negative response were somewhat more common among the adoptive parents. These findings confirm the author's belief that adoption practices, which in all but 4 states include permanent sealing of birth records, should be changed to recognize the life-long nature of adoption. Their recommendations include opening the records for adult adoptees, creation of agencies to be available to provide assistance and counseling for all involved (adoptees, their adoptive parents, and birth parents), and consideration of new adoption methods that would not require biological parents to forever relinquish their child and all knowledge of him/her at adoption.

Adoption↗