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Biomedical subjects

A Bansal

Publications and source records attributed to A Bansal.

95 records · Page 6Linked to original sources
PubMedDate not supplied

Cardiac complications of human immunodeficiency virus infection: diagnostic and therapeutic considerations.

Cardiac disease is being recognized as a complication of human immunodeficiency virus (HIV) infection, as more effective therapy is producing longer survival in patients with HIV infection and acquired immune deficiency syndrome (AIDS). Cardiac disease may occur coincidentally in a patient with AIDS, as a complication of AIDS, as a result of therapy for AIDS, or even as a direct result of HIV infection of the heart. Congestive heart failure (CHF) carries a poor prognosis and is best treated with traditional therapy. All patients with HIV/AIDS should get a baseline echocardiogram and electrocardiogram (ECG), because many patients are asymptomatic. Patients with low CD4 counts, those receiving zidovudine, and intravenous drug users must be further evaluated. Most patients with symptomatic effusions have a potentially treatable cause (neoplasm or infection), and a full workup must be initiated; however, small asymptomatic effusions often can be observed and followed by serial echocardiography. Physicians should be more alert to cardiac involvement in patients with HIV. Earlier surveillance is warranted and may lead to earlier treatment and supportive care.

Autoimmunity↗
PubMedDate not supplied

Serum adenosine deaminase in pulmonary tuberculosis, malignancy and non-tubercular respiratory diseases.

The study has been conducted to find out the serum ADA levels in 120 patients with various pulmonary diseases which included patients with tubercular pleural effusion (n = 86), lung cancer (n = 10) and patients with non-tubercular pulmonary diseases like pneumonia, etc (n = 24). Twenty healthy individuals served as control subjects. The mean (+/- SD) of ADA activity was 23.38 (4.47), 7.29 (1.08), 12.71 (1.95) and 2.23 (1.00) units/litre in tuberculosis, malignancy, non-tubercular pulmonary diseases and healthy controls respectively with significant difference between each other (P less than 0.001). Patients with tuberculosis (100%) fall in 97% sensitivity range with a lower cut off limit at 17 units/litre ADA activity, while for malignancy and non-tubercular respiratory diseases, the sensitivity was 90% and 83% respectively. Within the sensitivity limits, the serum ADA activity can be used for the differential diagnosis of pulmonary diseases.

Adenosine Deaminase↗