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Biomedical subjects

A B Weitberg

Publications and source records attributed to A B Weitberg.

59 records · Page 4Linked to original sources

The effect of L-2-oxothiazolidine on glutathione levels in cultured mammalian cells.

Chinese hamster ovary cells were cultured with increasing concentrations (7 X 10(-8) M-7 X 10(-2) M) of L-2-oxothiazolidine in an attempt to increase intracellular glutathione levels in these multiply-passaged mammalian cells. In a series of 7 Expts., intracellular glutathione levels increased significantly at the highest concentrations tested and were protective against oxygen radical-induced genetic toxicity.

Animals↗

Metastatic islet cell carcinoma: a potentially treatable cause of "carcinoma of unknown origin.".

A 55-year-old woman presented with diplopia secondary to an orbital mass. Physical examination showed a large ovarian mass. Further evaluation revealed these lesions to be metastases from a nonfunctioning pancreatic islet cell carcinoma, the first such case reported. Since these tumors can be responsive to chemotherapy, it is important to consider islet cell cancers in patients presenting with "metastatic carcinoma of unknown origin.

Adenoma, Islet Cell↗