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Biomedical subjects

A B Salter

Publications and source records attributed to A B Salter.

6 recordsLinked to original sources
PubMed2004

Designing follow-up intervals.

When an examination is needed to determine if an event has occurred there will be a loss of efficiency in using the resulting interval-censored data instead of the exact event times. In designing follow-up intervals this loss for longer intervals needs to be weighed against extra visits required by shorter intervals. We obtain results to quantify this for the estimation of the median and mean survival and for covariates in parametric regression models with equally spaced examination times. Asymptotic information loss for the log-normal and Weibull distributions are similar when comparisons are made between corresponding members of the two families. For distributions with coefficients of variation of 50 per cent or more, a choice of interval from 0.25 to 0.7 times the median is recommended.

Administration, Topical↗
PubMed1983

Autosomal dominant iridogoniodysgenesis: glaucoma management.

In a family of 55 people in seven generations 28 were known to be affected with autosomal dominant iridogoniodysgenesis. Their glaucoma was characterized by early onset of high intraocular pressures, lability of the pressure both with and without medical treatment, poor response to such treatment and resistance of the optic nerve head to damage even into early middle age. Among the surgical procedures undertaken, goniotomy was not successful but, oddly, iridencleisis was. All indications were that surgery could be delayed into adult life.

Adolescent↗
PubMed1983

Autosomal dominant iridogoniodysgenesis: genetic features.

Twenty-two members of two families have been identified as being affected with iridogoniodysgenesis. The major clinical features of this disorder are mesodermal remnants in the iridociliary angle associated with abnormal angle vasculature, marked hypoplasia of the iris stroma and increased intraocular pressure leading to glaucoma. The involvement of the two eyes is remarkably symmetric. Pedigree analysis of the larger family provided firm evidence for regular autosomal dominant inheritance as the mechanism of genetic transmission.

Adult↗