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Biomedical subjects

A B Jones

Publications and source records attributed to A B Jones.

95 records · Page 6Linked to original sources

Analysis of the major metabolite of delta 9-tetrahydrocannabinol in urine. V. Cross-reactivity of selected compounds in a radioimmunoassay.

The potential for cross-reactivity of an antiserum used to detect 11-nor-delta 9-tetrahydrocannabinol-9-carboxylic acid in a urine sample by a radioimmunoassay procedure has been examined. The degrees of cross-reactivity of 41 cannabinoids and non-cannabinoid phenolic constituents of Cannabis have been determined. In general, only (delta 8- or delta 9-THC type) cannabinoids of the dibenzopyran type structure were found to appreciably cross-react with the antiserum. Cross-reactivity was not observed with any non-cannabinoid constituent.

Cannabinoids↗

Study of the concentration of the herbicide (2,4-dichlorophenoxy)-acetic acid in coca leaves and paste obtained from plants treated with this herbicide.

The herbicide (2,4-dichlorophenoxy)-acetic acid (2,4-D) is considered to be the most cost-effective for eradicating illicit coca plants. Since coca leaves are chewed by the natives of coca producing areas, and, since coca paste and cocaine are widely abused, a study was undertaken to determine whether 2,4-D is translocated into the leaves and transferred to coca paste when coca plants are treated with this herbicide. The study concluded that basal treatment of coca plants with 2,4-D ester resulted in translocation of 2,4-D into the leaves, and this herbicide was detected in high concentrations one week after treatment. Coca paste prepared from leaves obtained from basally treated plants did not contain 2,4-D. Foliage spraying resulted in extremely high concentrations of 2,4-D in the leaves, with significantly high concentrations of the herbicide found one week after spraying. Trace amounts of 2,4-D were detected in coca paste prepared from plants sprayed by the foliage method.

2,4,5-Trichlorophenoxyacetic Acid↗

Hospice and the AMA.

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American Medical Association↗