Primary hepatic vascular leiomyosarcoma of probable portal vein origin.
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Biomedical subjects
Publications and source records attributed to A B Akosa.
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Primary plasmacytoma of the thyroid is a very rare tumour. We report a case and emphasize the importance of excluding multiple myeloma which may present as an extramedullary plasmacytoma. Histological diagnosis has been simplified by the use of immunohistochemical techniques.
A synchronous presentation of an adenocarcinoma and a primary low grade B cell lymphoma of the stomach is reported in a 79 year old man. Both diagnoses were made on endoscopic biopsies and immunocytochemistry was essential in confirming the lymphoma. The true incidence, aetiology and spatial relations of these tumours are unknown since only few cases of such synchronous gastric tumours have been reported in the literature.
An uncommon origin of a rare tumor is described in a 60-year-old white man. Extramedullary plasmacytoma was localized in the left biceps muscle. Tumor immunostaining corresponded with immunocharacterization of the atypical midgamma band on electrophoresis or the serum monoclonal M protein of IgG kappa. The latter disappeared 6 months after the operation. The diagnosis was confirmed ultrastructurally.
Idiopathic scrotal calcinosis is characterised by the presence of multiple firm scrotal nodules of unknown or disputed aetiology. Only 55 cases have been reported in the literature since the first description by Lewinski (1883). We report an additional five patients. We have reviewed the literature exhaustively and our findings support the suggestion that the lesions of "idiopathic" scrotal calcinosis result simply from dystrophic calcification of epidermal cysts.
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The concurrence of a paraganglioma of the organ of Zuckerkandl and an abdominal aortic aneurysm is reported in a 72-year-old caucasian male. Computerized tomography scan confirmed the aneurysm and noted a well-circumscribed tumour of the aneurysmal wall. At operation, the tumour was identified and excised with part of the aneurysmal wall. The tumour exhibited all the features of a paraganglioma while the vessel wall showed atherosclerosis and secondary degenerative changes. The features of the aortico-sympathetic group of paragangliomas are discussed.
This report describes two cases of Henoch-Schönlein purpura with unusual lymph node pathology. The patients presented with severe colicky abdominal pain mimicking acute appendicitis but a normal appendix was removed in each case. Enlarged mesenteric lymph nodes were removed, with a clinical suspicion of Yersinia infection. Cultures and serology were negative. Histological examination of the lymph nodes revealed follicular granulomas, follicular microabscesses and leucocytoclastic vasculitis. Immunohistochemical studies revealed deposition of IgA, IgG and C3 in the vessel walls, the finding of IgA supporting a diagnosis of Henoch-Schönlein purpura.
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Merkel-Cell carcinoma is a rare malignant skin tumour. It was first described as 'Trabecular Carcinoma' by Toker in 1972. Since then many reports have appeared in the literature, mainly in the dermatology, pathology and to a lesser extent, in the plastic surgery journals. Surprisingly, the topic is rarely discussed in the otolaryngology literature, though nearly fifty per cent of these tumours arise in the head and neck.
Leiomyoma of the nose and paranasal sinuses is rare. It constitutes about 1 per cent of all benign tumours. This is due to the paucity of smooth muscle in the nose. In this paper, the authors present one case of vascular leiomyoma which arose in the inferior turbinate in a 64-year-old lady. It was treated by partial turbinectomy with the relief of her symptoms of nasal obstruction, epistaxis and facial pain. The English literature on the topic is reviewed.
Cytologic investigations of 16 proven cases of gallbladder carcinomas were analyzed in order to establish the usefulness of cytological methods, including exfoliative bile cytology, fine needle aspiration and endoscopic brushing, in the preoperative and intraoperative diagnosis and management of gallbladder carcinoma. Fine needle aspiration cytology had a sensitivity of 88% and exfoliative cytology of bile a sensitivity of 50%, but both brushings performed yielded false negatives. A preoperative diagnosis was made in 69% (9/13) of cases, and cytologic diagnosis was helpful in planning surgical management. We recommend its wider application in the preoperative diagnosis of gallbladder carcinoma.