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Biomedical subjects

A Aviram

Publications and source records attributed to A Aviram.

100 records · Page 6Linked to original sources
PubMedDate not supplied

The relation between Apgar score and subsequent developmental functioning.

A randomly selected sample of 252 infants aged 5--18 months was evaluated through medical and developmental examinations. Developmental achievement scores and factors such as management of delivery and fetal distress were studied in relation to Apgar scores. Low-Apgar-score infants aged 5--8 months achieved consistently lower scores on all developmental fields. High-Apgar-score infants at younger and older ages did not differ on their achievement scores. Low Apgar score was much more frequent in infants delivered by vacuum extraction than in those delivered spontaneously, with forceps or by cesarian section. The frequency of low Apgar score was higher when fetal distress occurred.

Apgar Score↗
PubMedDate not supplied

Stimulation of polymorphonuclear leukocytes by dicyclohexylcarbodiimide: calcium homeostasis.

The involvement of calcium in N,N'-dicyclohexylcarbodiimide (DCCD)-mediated stimulation of guinea pig neutrophils was investigated. Exposure to DCCD resulted in a fast though moderate elevation of cytosolic calcium concentration. Exchange experiments indicated that DCCD enhanced 45Ca2+ efflux without affecting uptake of the radioisotope from the medium. Plasma membranes isolated from DCCD-stimulated cells failed to support ATP-dependent 45Ca2+ uptake indicating inhibition of their Ca-ATPase. The finding that the enhanced efflux of 45Ca2+ depended on the presence of Na+ ions in the medium implicated a Na+/Ca2+ exchanger in efflux of the ion observed in DCCD-stimulated neutrophils. This is the first indication for the participation of this carrier in calcium homeostasis in stimulated neutrophils. Experiments carried out with 14C-DCCD indicated covalent binding of the reagent to 20 and 150 Kd membrane proteins.

Adenosine Triphosphate↗
PubMedDate not supplied

Tubular necrosis complicating intravesical formaldehyde treatment.

Intravesical formaldehyde instillation for the treatment of profuse hemorrhage due to inoperable bladder carcinoma has been done for the last three years. Results have been satisfactory. Recently, an anuria developed after such treatment in a 76-year-old patient. Renal biopsy showed focal tubular necrosis. The possibilities of a toxic or an ischemic lesion are discussed. Diuresis reappeared spontaneously after six days and the patient was discharged from the hospital twelve days after the formaldehyde treatment.

Acute Kidney Injury↗