A case resembling broad thumb-hallux syndrome.
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Biomedical subjects
Publications and source records attributed to A Asaka.
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We have demonstrated an association between apolipoprotein E (apoE) gene polymorphisms and Alzheimer's disease (AD) in 163 Japanese patients by means of PCR. We found a significant increase in risk of nonfamilial AD for apoE allele epsilon4 in these individuals; this trend decreases with the increase in onset age. In centenarians, the distribution of apoE gene alleles is similar to that in the general population. The protective effect of allele epsilon2 against the development of AD is not statistically significant in our analysis. This indicates that apoE polymorphism is associated with AD regardless of race and that the age of onset is related to the apoE gene in the development of AD.
This is an initial report of a cooperative project by colleagues in Korea, the Republic of China (Taiwan) and Japan, involving the measuring of attitudes toward mental illness. The discussion mainly revolves around the influence of mental health education in nursing on attitudes towards mental illness. The subjects' attitudes were assessed by Wig's profiles. The attitudes of freshmen who had just entered nursing schools and seniors who had already finished clinical training in psychiatry were compared to measure the attitude change during the course of nursing education, if any. Non-medical students served as a control group. As a result, a seemingly "negative and pessimistic" attitude was demonstrated in the senior student nurses. The findings are examined and discussed.