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Biomedical subjects

A Ariyoshi

Publications and source records attributed to A Ariyoshi.

At least 37 records · Page 2Linked to original sources
PubMed1990

[A 17-year experience with ileal conduit urinary diversion--early and late complications].

A series of 185 patients, 133 males and 52 females, were treated by ileal conduit urinary diversion in the past 17 years. The patients ranged in age from 7 months to 81 years with an average of 59 years. Diversions were performed for malignant diseases in 174 patients, 85% of whom underwent a simultaneous radical surgery. The follow-up covered the postoperative period from 4 months to 16 years 8 months with an average of 4 years 8 months. Six patients (3%) died within 1 month of operation, and 43 of a total of 58 mortal cases died of cancer thereafter. The survival rates of 143 patients with bladder cancer were 84% for 1 year, 72% for 3 years, 67% for 5 years, 62% for 10 years and 54% for 15 years. Early complications were noticed in 38% of the patients. Delayed wound healing due to local infection (20%) and intestinal obstruction (10%) were the two major complications in this period. Late complications were encountered in 51% of the patients. Mild peristomal dermatitis (22%) and gradually developing renal complications (22%) are two major problems in the standard ileal conduit urinary diversion. The latter was significantly more frequent in patients who underwent the operation between 1973 and 1981 than in those who had the surgery between 1982 and 1989. Postoperative hydronephrosis was observed in 15 (13%) of 117 patients who showed normal urograms preoperatively. Ileoureteral reflux was observed in 50% of the cases with nonobstructing conduits, while it increased up to 70% along with obstruction of the conduit.(ABSTRACT TRUNCATED AT 250 WORDS)

Adolescent↗
PubMed1989

[Surgical treatment of renal cell carcinoma associated with pulmonary metastasis].

Fifty-nine nephrectomies have been performed in patients with renal cell carcinoma during a 15-year-period from 1973 to 1987 in Fukuoka University Hospital. Of whom 13 had pulmonary metastasis and 10 had other organ metastasis. The 1, 3, 5-year survival rates in patients with metastasis were significantly worse than those without metastasis. No significant difference was observed between the survival rates in patients with pulmonary metastasis and other organ metastasis. Only 1-year-survival rate was better in patients with delayed metastasis after nephrectomy than that of patients with synchronous lung metastasis to the primary tumor. Resection of pulmonary metastasis was performed in 6 patients. Four of them, however, underwent another resection for recurrence in the lung. The average survival periods of the patients with and without surgical removal of pulmonary metastasis were almost same in the alive cases, but in the dead cases there was observed a 26-month-longer survival period in patients undergoing resection of metastatic lesion than those without resection. In conclusion, resection of pulmonary metastasis may not bring eradication of the disease in the majority of cases. However, aggressive surgery for pulmonary metastasis should be accepted because no effective adjuvant therapy is practically available in the treatment of renal cell carcinoma. Additionally, a case was reported of spontaneous regression of a pulmonary metastasis seen in a 61-year-old male with renal carcinoma. The lesion showed an apparent regression after radical nephrectomy on chest films and completely disappeared at 8 months postoperatively. After 9 months disease-free period, heterotopic recurrence developed in the same lung.(ABSTRACT TRUNCATED AT 250 WORDS)

Carcinoma, Renal Cell↗
PubMed1989

Barium granuloma involving urinary bladder.

The first case of barium granuloma involving urinary bladder is reported. Surgical removal was the treatment of choice. Histological diagnosis was foreign body granuloma with xanthomatous inflammation. The foreign body was identified as barium by analytical electron microscopy.

Aged↗
PubMed1987

Early intravesical instillation of adriamycin with oral administration of 5-fluorouracil after transurethral resection for superficial bladder cancer: preliminary results.

In all, 199 patients were entered in this study by 21 collaborating hospitals. Patients with superficial transitional cell carcinoma of the bladder were randomized postoperatively into four groups. Group A received early (immediately and 2 days after transurethral resection) instillation of adriamycin (30 mg/30 mg); group B received early instillation of adriamycin with oral administration of 5-fluorouracil (200 mg/day); group C received delayed (7 days after transurethral resection) instillation of adriamycin (30 mg/30 ml); and group D received delayed instillation of adriamycin with oral administration of 5-fluorouracil (200 mg/day). All patients subsequently received instillations weekly for 2 more weeks, and then every 2 weeks for a further 14 weeks. After 4 months, they received one instillation per month for 8 months. 5-Fluorouracil was administered p.o. for 1 year. The postoperative follow-up period was 12 months. After 3 and 6 months there were significant differences in the non-recurrence rates between groups B and C. After 12 months the overall non-recurrence rates were 87.9% in group A, 83.5% in group B, 89.2% in group C, and 82.8% in group D, and there were no significant differences among the four groups. The number of patients entered and the follow-up period are not adequate for firm conclusions, and further studies are necessary. The main side effect was bladder irritation, which was observed in 38.8% of patients in the early instillation groups and in 26.3% of those in the delayed instillation groups. No severe systemic side effects were observed in this study.

Administration, Intravesical↗
PubMed1986

Chronic incomplete obstruction of the ureter: a new experimental model.

To produce a chronic moderate hydronephrosis in dog, a method of partial ureteral occlusion using a specially designed polypropylene obturator was developed. In 11 of 14 dogs undergoing this procedure, excretory urography constantly revealed a moderate degree of hydronephrosis persisting for 7 weeks. Combination of this method in one ureter with the vaginal-cuff cutaneous ureterostomy, previously reported, in the contralateral ureter is a useful model for split renal function study of unilateral chronic hydronephrosis or obstructive nephropathy analogous to that of clinical case.

Animals↗
PubMed1986

Does 'extended' pelvic lymphadenectomy truly contribute to the management of bladder carcinoma?

During a 3-year period, 41 patients with primary bladder carcinoma were treated with cystectomy along with pelvic lymphadenectomy. Although lymphadenectomy was useful for more accurate staging in patients with T2 or more invasive disease, it contributed little to the surgical curability of the disease, irrespective of extensive nodal dissection in the pelvis. Based on the characteristic lymphatic spread of the disease, limited dissection to the regional nodal area seemed to be satisfactory in the surgical management of bladder carcinoma.

Follow-Up Studies↗
PubMed1985

[Extended radical nephrectomy in renal carcinoma involving the inferior vena cava: a case report].

A case of successful removal of right renal cell carcinoma extending into inferior vena cava in a 62-year-old man was reported. The tumor thrombus reached the level of the liver and almost completely obliterated both caval and contralateral renal veins. With cooperation of cardiovascular and hepatic surgeons, the operation was performed under thoracoabdominal exposure. Extensive mobilization of the liver enabled us to regulate vena caval and hepatic blood circulation. The tumor thrombus, though partly adhesive to the caval vein, could be completely removed safely through a long cavotomy incision. To cope with the recent advance in more aggressive cancer surgery, it seems mandatory for urologists to acquire a broad knowledge of thoracic, cardiovascular and hepatic surgery as well.

Carcinoma, Renal Cell↗
PubMed1983

Muco-cutaneous ureterostomy: an experimental study for prevention of stomal stenosis using autograft of vaginal vestibular mucosa.

To prevent dermal invasion which causes gradual stomal stenosis in cutaneous ureterostomy, transplantation of autologous vaginal vestibular mucosa around the ureteral opening was examined in 9 female dogs. Results of a full-thickness graft to a full-thickness skin bed were hopeful. Though surface keratinization occurred, the thick graft survived well on the abdomen without obvious shrinkage, and the ureteral patency was maintained through the follow-up period with an average of 18 months. This method seemed to be applicable to clinical patients and to dog experiments as a model for separate renal function study.

Animals↗
PubMed1983

Vaginal cuff cutaneous ureterostomy as a model for split renal function study in dog.

To protect ureteral stoma from necrosis and stenosis in cutaneous ureterostomy, an autograft of the entire vaginal wall to the canine abdomen was investigated. The patency of the ureteral stoma was well preserved for the observation period with an average of 9.4 months in 20 of 29 dogs. A combination of unilateral vaginal cuff cutaneous ureterostomy with bladder urine collection for the contralateral kidney is a useful experimental model for split renal function study. The value of this model has been shown by clearance study using the separate urine obtained from each kidney.

Abdomen↗
PubMed1982

Postoperative prophylactic intravesical instillation of cytosine arabinoside and mitomycin C in superficial bladder tumor. A follow-up study.

A follow-up study was made on 225 Japanese patients with superficial bladder tumors who were treated postoperatively with intravesical instillation of cytosine arabinoside and mitomycin C nineteen times during one year. Cumulative recurrence rates of the tumor were 16.7 and 41.9 per cent during the first 1 and 3.5 years after surgery, respectively. These results are superior to the previous findings in cases in which instillation therapy was not given. Histologically, there was no definite difference in recurrence among the groups with low-grade and high-grade tumors. The recurrence rate of multiple tumors was higher than that of a solitary tumor. Earlier postoperative instillation appeared to be more effective during the initial one year after surgery.

Adult↗