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Biomedical subjects

A Appleby

Publications and source records attributed to A Appleby.

26 records · Page 2Linked to original sources

A stereotaxic apparatus for injection of the trigeminal root and ganglion.

A stereotaxic apparatus was designed which would enable a needle to be passed easily through the foramen ovale with accuracy and with a minimum of radiological aid by one relatively unskilled in injection of the trigeminal ganglion. Successful penetration of the foramen was achieved in 39 of 46 injections on cadavers and in six injections on five patients. The substance injected was 5% phenol in glycerin. In one patient alcohol was used. The anesthesia produced was satisfactory in all except one patient. We feel that this apparatus will enable the trigeminal ganglion to be injected relatively easily in all patients except those with unusually shaped skulls.

Humans↗

Imaging of spatial radiation dose distribution in agarose gels using magnetic resonance.

Radiation dose distributions are conventionally measured using ionization chambers or diodes in liquid phantoms, or in two dimensions using film. This work describes a new application of magnetic resonance imaging to radiation dose planning. Agarose gels containing ferrous sulfate, sulfuric acid, and benzoic acid have been irradiated with 137Cs gamma rays and 6-14 MeV electrons, to doses of up to 20 Gy. The dose distributions have been imaged by magnetic resonance, making use of the effect on the T1 proton relaxation times of the radiolytic Fe3+. The image intensity was proportional to doses of up to 10 Gy, and images were stable for at least 24 h postirradiation. The G value for Fe3+ production was about 100 (molecules per 100 eV absorbed).

Cesium Radioisotopes↗

Imaging of radiation dose by visible color development in ferrous-agarose-xylenol orange gels.

Imaging of radiation dose distribution in gel phantoms by magnetic resonance techniques has previously been reported. In this paper a method of producing gels in which the distributions of radiation dose can also be visualized as a color change is reported. The color developed depends qualitatively and quantitatively on the concentrations of solutes in the gel.

Color↗