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Biomedical subjects

A Amdisen

Publications and source records attributed to A Amdisen.

At least 73 records · Page 4Linked to original sources

Lithium and pregnancy. II. Hazards to women given lithium during pregnancy and delivery.

The renal lithium clearance of a manic-depressive woman rose when she became pregnant and fell to the prepregnancy level when she gave birth. The lithium clearances of four healthy women were higher during pregnancy than after delivery. This emphasizes the need for frequent determinations of the serum lithium concentration and appropriate dosage adjustments during pregnancy and delivery.

Bipolar Disorder↗

Lithium in pregnancy.

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Abnormalities, Drug-Induced↗

Occurrence of goitre during lithium treatment.

Of 330 patients given lithium for recurrent manic-depressive disorder 12 developed goitre after treatment periods of five months to two years. All the patients remained clinically euthyroid. Pressure symptoms necessitated subtotal thyroidectomy in two patients. In 9 out of 10 patients with goitre, and in two out of seven without goitre study with radioactive iodine showed abnormal findings in iodine metabolism. Discontinuance of lithium led to disappearance of goitres, while thyroid metabolism returned to normal. Thyroxine or desiccated thyroid produced shrinkage of the gland in spite of continued lithium medication.

Adolescent↗