Search PubMed⌕ Search

Biomedical subjects

A Alvi

Publications and source records attributed to A Alvi.

46 records · Page 3Linked to original sources
PubMed1992

Primary salivary gland amyloidosis causing sicca syndrome.

Sicca syndrome (SS), consisting of xerostomia and xerophthalmia, may be caused by various disease processes. We present a unique case of SS secondary to primary amyloidosis. Amyloidosis is a rare but definite cause of SS and should be included in the differential diagnosis of any patient who presents with sicca symptoms. A literature review comparing amyloidotic patients with SS and patients with amyloidosis only demonstrates that both of these groups of patients present similarly with regard to symptoms. However, the majority of patients with SS present with sicca symptoms initially in addition to symptoms of amyloidosis. These SS patients also present with proteinuria and negative serology test results. Therefore, patients presenting with sicca symptoms, proteinuria, and negative serologic findings should be suspect for amyloidosis. The importance of distinguishing the diagnosis of Sjögren's syndrome from SS in these patients cannot be overemphasized. There is a significantly higher incidence of developing a lymphoma in Sjögren's syndrome patients. This has important implications for the head and neck surgeon treating these patients.

Aged↗
PubMedDate not supplied

Parathyroid cyst: current diagnostic and management principles.

BACKGROUND: Parathyroid (PTH) cyst is a rare lesion. Only about 200 cases have been reported to date. The diagnosis of a PTH cyst is difficult, particularly in its differentiation from thyroid cyst. It has clinical significance because PTH cysts can mimic a thyroid mass and can be associated with hyperparathyroidism. METHODS: This presentation illustrates an additional case of a PTH cyst. The importance of fine-needle aspiration (FNA) in the diagnosis of PTH cyst and its management are discussed. RESULTS: Fine-needle aspiration of clear fluid containing an elevated PTH hormone level proved to be diagnostic in the patient. Recurrence of the cyst after FNA required surgical resection. The current concepts of etiology and treatment are summarized. CONCLUSIONS: PTH cyst should be in the differential diagnosis in any patient initially seen with an anterior cystic neck mass. Radiologic imaging and FNA can accurately diagnose PTH cysts. Surgical excision may be needed for recurrent cysts after aspiration.

Adult↗
PubMedDate not supplied

Skin graft reconstruction of the composite resection defect.

BACKGROUND: Reconstruction of the composite resection defect should provide for adequate speech and swallowing functions. Poorly designed reconstructive efforts can result in significant oral dysfunction. The composite resection defect can be reconstructed by a variety of methods. The split-thickness skin-graft method provides excellent speech and swallowing functions with minimal morbidity. METHODS: Forty-three patients who underwent composite resections and were reconstructed by split-thickness skin graft (STSG) were analyzed. The patients' charts were reviewed for oncologic outcome, speech and swallowing functions, and length of hospital stay. RESULTS: Speech and swallowing functions were excellent. At last follow-up, more than 90% of the patients tolerated either a soft or regular diet. The length of hospital stay was only 13 and 18 days for patients who underwent marginal and lateral segmental mandibulectomy, respectively. There were few complications. Radiation therapy had no adverse effects on the grafts. CONCLUSION: The STSG method is our preferred method for reconstruction of marginal or lateral segmental mandibulectomy defects that do not require tissue bulk.

Aged↗
PubMedDate not supplied

Sternocleidomastoid myofascial flap for head and neck reconstruction.

BACKGROUND: The use of the sternocleidomastoid (SCM) muscle in the repair of soft tissue defects arising after surgery for neoplasms of the head and neck has been a subject of controversy. We describe a variant of the SCM muscle flap called the "SCM myofascial flap" and report our experience with this flap in head and neck reconstruction. METHODS: Six patients underwent head and neck reconstruction with the SCM myofascial flap. The head and neck defects included partial laryngeal, pharyngeal defects, and concave soft tissue neck defects after resection. RESULTS: Follow-up of the patients ranged from 6 to 91 months. In the case of laryngeal and pharyngeal reconstruction, all had a good voice and were able to eat by mouth without aspiration. Two of the four patients were decannulated. The only complication was a laryngo-cutaneous fistula. CONCLUSION: We have used this flap with success, in soft tissue augmentation and in laryngeal and pharyngeal reconstruction following tumor resection. The technique and the results of our experience are discussed. We believe that in selected cases, the SCM myofascial flap is ideal for reconstruction of head and neck defects.

Aged↗