Inclusion bodies in cells from a hydatidiform mole.
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Biomedical subjects
Publications and source records attributed to A Alvarez.
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We report a 44 year old male suffering from rheumatoid arthritis that developed myokymias when treated with gold salts. Myokymia is a clinical phenomenon characterized by involuntary repetitive contractions of muscle fibres, which give an undulating appearance to the overlying skin, last a few seconds, and with a typical electromyographic activity described as myokymic discharges. The difference between the single twitch of the fasciculation and the tetanic contraction of myokymia may be evident only on electromyography in difficult cases. Neurological complications associated with gold are infrequent, and they include myokymia, peripheral neuropathy, Guillain-Barré syndrome, cranial nerves paralysis and encephalopathy.
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We asked 53 elderly hypertensives from our outpatient clinic which and how many drugs they took, and analysed factors that could have affected the intake, as sex, age and school instruction. The most frequent drug groups found were, in decreasing order, antihypertensives, benzodiazepines, nitrates and non-steroidal anti-inflammatory drugs. 53.3% of the patients took only angiotensin converting enzyme inhibitors and/or calcium-channel antagonists as antihypertensive drugs. Twenty four patients used occasional medications, sometimes as much as 6 different drugs, specially analgesics, antipyretics and anti-inflammatory agents. These patients took, in mean, 5.2 different drugs daily, 2.1 of which antihypertensive, in a total of 8.5 pills. Females took more drugs (9.4 +/- 3.6 pills per day against 7.1 +/- 3.0 in the male gender, Z < 0.03). Age and school instruction did not affect the intake.
The time has come for humans to return the debt to the many non-human species that were studied for the sake of humanity and to extend the motto of "doing unto oneself first what eventually is to be done to others" when the "others" are the patients of veterinarians. As physiologic monitoring benefits from advances in hardware and software, much chronobiologic information can be obtained on the chronomes of the different species cared for by veterinarians for a new health care focusing on prevention, implemented perhaps by recognizing and treating earliest rhythm alteration rather than merely the fact of overt disease.
A 20-year-old female patient who presented papylo-erythematous lesions with intense pruritus and arciform sinuous lesions in the back and gluteal regions during a stay at a beach is presented. A cutaneous larva migrans was diagnosed through biopsy. A brief bibliographic review of this parasitologic entity is made.
The persistence of passively adquired measles hemagglutination-inhibition (HI) antibody, was studied in a group of 50 mother-child binomials. In this longitudinal study, serial samples of blood were obtained from each infant during the first eight months of life. There was a high correlation between the level of the antibody titer in mothers and in their newborns. Passively antibody titers between 1:20 to 1:80, persisted as late as 8 months in more than 60% of infants. The presence of antibody may have a suppressive effect on the immunogenic response to live measles virus vaccine.
The experience of the human being towards death is reviewed in this essay. Some historical, medical and psychological points of view are analyzed. It is disquieting to note that the death theme, as well as the experience of patients who confront their own death, are forgotten topics and occasionally even vetoed by patients and physicians. We consider that is timely and important to reflect about death. The advancement of medical technology must walk in parallel with physician-patient relationship. Who, if not the doctor, is to help his patient to die in comfort?
This study evaluated fracture resistance provided to complex amalgam restorations by adhesive and mechanical resistance features. The occlusal surfaces of 30 extracted molar teeth of similar size were ground flat to approximately 2 mm coronal to the CEJ. The teeth were divided into three groups. Roots were notched and embedded in acrylic resin. In two groups, four TMS Minim stainless steel pins were placed into dentin at the line angles. A copper band matrix was applied to each specimen and reinforced with compound. After applying either Copalite or Amalgambond Plus, Tytin amalgam was condensed into the matrix. The bands and excess amalgam were removed 10 minutes later, and each amalgam occlusal surface was ground flat to give the amalgam restoration a 4 mm occlusal height. Specimens were thermocycled for 2500 cycles at 6-60 degrees C with a 30-second dwell time. They were then stored in deionized water for 1 month at room temperature. A 1 mm 45 degrees bevel was placed on the facio-occlusal angle of the amalgam. Each specimen was loaded to failure in compression at 45 degrees in an Instron Testing Machine at a crosshead speed of 5 mm/min. The groups were: Group 1, four Minim pins and Copalite; Group 2, four Minim pins and Amalgambond Plus; and Group 3, Amalgambond Plus only. The data were analyzed using a one-factor ANOVA and a Tukey B post hoc test. There was no significant difference between Groups 1 and 3. The Amalgambond Plus combined with pins provided significantly greater resistance to fracture than pins or Amalgambond Plus alone (P < 0.05).
A brief review of some ethical issues related to the advancement of science and technology is presented. The principles currently considered priorities for a healthy relation between patient and physician are discussed, including autonomy, intimacy and respect. In addition, due to the linkage between psychoanalysis and medicine, some elements that determine the ethics of psychoanalysis-such as transference-are analyzed in order to consider their vinculations with the physician-patient relationship. Important corollaries emerge, i.e. the physician must not forget that he deals with a person, that illnesses have particular meanings to patients who also have particular needs, questions and wishes of his or her own.
A 6-month double-blind, prospective, randomized, placebo-controlled trial was conducted to establish the safety and efficacy of OM-85-BV in the treatment of subacute sinusitis and in the following prevention of the respiratory tract infections in 56 children from 18 months to 9 years of age. In the subacute phase of the sinusitis the patients were given one OM-85-BV capsule (3.5 mg of bacterial extracts) (n = 26) or placebo (n = 30), daily for ten days; additionally both groups took amoxicillin/clavulanate 40/10 mg/kg daily in three divided doses for 21 days. For the following two months the patients took one OM-85-BV capsule or placebo, ten days a month. In the subacute phase the OM-85-BV group of patients improved sooner (5.56 +/- 4.98 vs 10 +/- 8.49 days) and had a shorter convalescence (15.38 +/- 8.91 vs 20.28 +/- 7.17 days). During the six month follow-up the patients in the OM-85-BV group had a lower number of infections (1.56 +/- 0.3 vs 2.22 +/- 0.43) and required a lower number of drug treatments (1.47 +/- 0.32 vs 1.94 +/- 0.42). One patient treated with OM-85-BV presented a mild rash which disappeared three days after the drug discontinuation. We conclude that OM-85-BV is safe at pediatric ages, as well as accelerates the cure and improvement of subacute sinusitis while it lowers the incidence of respiratory infections.