Search PubMed⌕ Search

Biomedical subjects

A Alonso

Publications and source records attributed to A Alonso.

At least 487 records · Page 27Linked to original sources
PubMed1981

Constancy of liver lipid composition in two genera of toads after a short-term temperature acclimation.

The lipid and fatty acid composition of Bufo calamytes and Alytes obstetricans livers has been studied. Data for both species are similar, and resemble closely those published for Rana sculenta. Total lipids constitute 20-25% of the total liver dry weight; about one fifth of these are phospholipids; cholesterol makes up 1.7-2.2% of the total liver dry weight. The most abundant phospholipids are phosphatidylcholine and phosphatidylethanolamine. The various lipid cases differ in their fatty acid composition: neutral lipids contain high proportions of palmitoleic and linoleic acids; phosphatidylcholine is characterized by its contents in palmitic acid, whereas cardiolipin contains polyunsaturated fatty acids. Thermal acclimation of toads for 96 h produces but few changes in liver lipid composition.

Acclimatization↗
PubMed1981

Structural analysis of hnRNP particles approached by in vitro phosphorylation using exogenous protein kinase and l gamma 32 P1 ATP.

Using an exogenous kinase, nuclear ribonucleoprotein complexes with sedimentation coefficients greater than 100S were phosphorylated in vitro before and after treatment with increasing concentrations of NaC1. The phosphorylation pattern of the proteins before raising the NaC1 concentration shows a major group of labelled proteins in the 30 000 to 40 000 MW range. Treatment of the complexes with 400 and 800 mM NaC1 produces a relative increase in the labelling of some polypeptides with the appearance of new labelled bands and the concomitant disappearance of several proteins. Even at the highest salt concentration used (1.2 M), it is still possible to identify a group of labelled polypeptides which are suggested to form the backbone structure of the nuclear RNP complexes.

Adenosine Triphosphate↗
PubMed1980

Albumin messenger RNA after partial hepatectomy and sham operation.

Albumin mRNA was quantified in nuclear RNA and in polysomal and post-polysomal poly(A)-containing RNA from untreated, hepatectomized and laparotomized rat livers. A prominent reduction of albumin-specific RNA sequences was observed in all subcellular fractions 50 h after partial hepatectomy, compared to both untreated and sham-operated livers. Surprisingly, laparotomy itself also induced a dilution of albumin-specific sequences at earlier times after operation in nuclei and in post-polysomal supernatant, but not in polysomes.

Albumins↗
PubMed1980

Comparison of polysomal and nuclear poly(A)-containing RNA populations from normal rat liver and Novikoff hepatoma.

Polysomal and nuclear poly(A)-containing RNA of normal rat liver and Novikoff hepatoma cells have been compared by cDNA.RNA hybridization kinetics. Homologous hybridization reactions revealed at total kinetic complexity of about 1.6 X 10(10) and 1.38 X 10(10) daltons for liver and Novikoff mRNA respectively. The high abundance component present in liver cannot be detected in Novikoff. It was found from heterologous reactions that about 30% by weight of mRNA sequences are specific to liver. Determination of the nuclear poly(A)-containing RNA complexities revealed that about 5.5% and 4% of the haploid genome is expressed in the liver and Novikoff respectively. In a heterologous reaction, up to 30% of the liver cDNA failed to form hybrids with Novikoff nuclear RNA. Cross hybridizations have further revealed abundance shifts in both nuclear and polysomal RNA populations. Some sequences abundant in liver are less abundant in Novikoff and some rare liver sequences are relatively abundant in Novikoff.

Animals↗
PubMed1980

Radiological Diagnosis of Periventricular and Subcortical Leukomalacia.

Nine newborn infants with histories of perinatal asphyxia are presented. The pneumoencephalographic findings which led to the diagnosis are typical and constant. They include marked subcortical atrophy with rounded, dilated, and undisplaced lateral ventricles. Cystography with 3 cc of air demonstrated multiple subcortical and pareventricular cavities, without communication with the ventricular system, but with the typical honeycomb appearance of paraventricular and subcortical leukomalacia described in postmortem findings. The CT findings are typical, and provide the location of the cavities as well as their density.

Birth Weight↗
PubMed1980

[Down's dyndrome and congenital heart disease (author's transl)].

Out of a group of 113 cases of Down's syndrome 50 were associated with congenital heart disease, confirmed by haemodynamic, angiographic and surgical means. The mean age was 36.6 months. Twelve were cyanotic, six of them because of an inverted previous left-toright shunt. The endocardial cushion defect, alone or in association, accounted for 40% of these anomalies, and ventricular septal defect for 26%. If the cases with right ventricle outflow obstruction are excluded, 50% presented pulmonary pressures over 70 mmHg. In addition, 80% of endocardial cushion defects presented pulmonary hypertension, being the three fourths under one year of life. On the basis of the data presented, authors remark the need of an early approach to specialized diagnosis of these children, in order to allow an earlier surgical correction or palliation than in children without Down syndrome.

Child↗
PubMed1980

Absorption and fate of canthaxanthin in chicken.

Male Hubbard chickens were fed on a diet supplemented with canthaxanthin. The carotenoid was chemically unmodified during its absorption of distribution. Pigment was preferentially stored in the skin of legs. The percent distribution of carotenoid in the different organs did not vary with the administered dose or during the treatment. Digestibility, expressed as the ratio absorbed: ingested pigment, was maximal in the first day, and then decreased. Digestibility was dependent on the animal body weight.

Animals↗