[Serum bile acids in chronic liver disease. II: liver cirrhosis].
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Bile Acids and Salts↗
Biomedical subjects
A Alberti
Publications and source records attributed to A Alberti.
Changes in auditory P3 event-related potentials in uremic patients undergoing haemodialysis.
A study on event-related P300 potential (ERPs) was performed in 20 patients suffering from chronic uraemia and undergoing haemodialysis in order to assessing the functioning of their cognitive processes. The patients were evaluated before and after a standard treatment of haemodialysis. The P300 potential was studied by means of the "oddball" paradigm and the acoustic modality. Moreover the patients' performance was assessed on the basis of the following psychological tests: the Mini Mental Test, the Number Connection Test and the Digit Span of the Wechsler Adult Intelligence Scale. A significant improvement in the P3 latency was demonstrated following the dialysis treatment. Even though a slight improvement in the N2-P3 deflexion amplitude was recorded after dialysis, it was not statistically significant. These data indicate a positive modification in the speed of the cortical function as a consequence of dialysis. These results suggest that the P3 latency obtained from auditory stimuli can help to assess the benefits obtained through extracorporeal dialysis, especially in the follow-up to the illness.
Acoustic Stimulation↗
[Spinal anesthesia in cesarean section: 1% versus 0.5% hyperbaric bupivacaine].
AIM: To compare the quality of anesthesia produced by the intrathecal administration of equivalent doses of 0.5% and 1% hyperbaric bupivacaine in patients undergoing cesarian section. EXPERIMENTAL DESIGN: A prospective, comparative and randomised clinical study. SETTING: Anesthesia Unit-Non-university civil hospital. PATIENTS: 50 patients undergoing elective or emergency cesarian section randomly assigned to two groups of 25 patients each. SURGERY: After prehydration, subarachnoid access was achieved through space L2-L3 or L3-L4 using a 24G Sprotte's needle with patients in right hand lateral decubitus. Patients in group A were injected with 1.25 ml of 1% hyperbaric bupivacaine and those in group B with 2.5 ml of 0.5% hyperbaric bupivacaine (12.5 mg). Patients were positioned immediately in partial decubitus on their left hand sides and ephedrine infusion, or if required i.v. bolus, was commenced to counter hypotension (SAP < 80% basal). MEASUREMENTS: ECG, pulse measurement, arterial pressure with non-invasive method, metameric level of analgesia (pin prick), motor block of lower limbs (Bromage's scale), time lapsed between induction of anesthesia and extraction of neonate, Apgar score, quantity of ephedrine used, duration of surgery, respiratory complications, insufficient analgesia, resolution of motor block, any postspinal cephalea. STATISTICAL ANALYSIS: Variance analysis, Student's t-test, chi 2. RESULTS: Both solutions guaranteed satisfactory intraoperative analgesia in 96% of cases. No statistically significant differences were noted between the two groups relating to the maximum duration of analgesia, the extent of motor block, induction times and regression, incidence of complications. CONCLUSIONS: No important difference was observed in the quality of the anesthesia obtained using the intrathecal administration of equivalent doses of 1% and 0.5% solutions of hyperbaric bupivacaine in patients undergoing cesarian section. In view of the possible relationship between the neurotoxicity of local anesthetics and the concentration of the solution used for spinal anesthesia, it is to be hoped that less concentrated solutions of hyperbaric bupivacaine will be introduced in Italy compared to the 1% solution currently available.
Adult↗