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Biomedical subjects

A Akin

Publications and source records attributed to A Akin.

44 records · Page 3Linked to original sources

The value of the basal temperature chart in the management of infertility.

The basal temperature chart (BTC) has been used as a means of screening the ovarian function of infertile patients and for monitoring their response to ovarian stimulation. During three years in a busy infertility clinic, specifically designated for cases of functional infertility, 491 patients were seen and 96 per cent of them kept valid basal temperature charts. The use of the BTC enabled therapy to be instituted early on in the course of investigations in those cases of infertility in which there was an endocrine factor. There were 420 patients in this category; of those who received treatment a high percentage became pregnant in contrast to those who were being observed. It is recommended that the BTC should be used early and more frequently in the management of cases of infertility, since it has been shown to serve as an inexpensive and convenient parameter of ovarian function.

Anovulation↗

Propofol and propofol-ketamine in pediatric patients undergoing cardiac catheterization.

We investigated the effects of propofol and propofol-ketamine on hemodynamics, sedation level, and recovery period in pediatric patients undergoing cardiac catheterization. We performed a prospective, randomized, double-blind study. The study included 60 American Society of Anesthesiologists physical status II or III (age range, 1 month-13 years) undergoing cardiac catheterization for evaluation of congenital heart disease. Propofol and ketamine were prepared in 5% glucose solution to a final concentration of 5 and 1 mg/ml, respectively; similar injectors containing 5% glucose solution only were prepared. Fentanyl (1 microg/kg) and propofol (1.5 mg/kg) were given to both groups. Then, group 1 received 0.5 ml/kg of 5% glucose and group 2 0.5 ml/kg of ketamine solution by an anesthesiologist who was unaware of the groups of patients. Local anesthesia with 1% lidocaine was administered before intervention in all patients. The noninvasively measured mean arterial pressure, heart rate, respiratory rate, and peripheral oxygen saturation were recorded at the baseline, following drug administration, at 3, 5, 10, 15, 20, and 30 minutes and then at 15-minute intervals until the end of the procedure. Additional drug and fentanyl requirements to maintain a sedation level of 4 or 5 were recorded. After the procedure, the time to a Steward recovery score of 6 and adverse effects in the first 24 hours were recorded. The number of patients with more than a 20% decrease in mean arterial pressure was 11 in group 1 and 3 in group 2 (p < 0.05). The number of patients who experienced more than a 20% decrease in heart rate was 12 in group 1 and 5 in group 2 (p = 0.054). Ten patients in group 1 and 3 patients in group 2 required additional fentanyl doses (p = 0.057). The number of additional propofol doses was lower in group 2 (p < 0.05). Propofol combined with low-dose ketamine preserves mean arterial pressure better without affecting the recovery and thus is a good option in pediatric patients undergoing cardiac catheterization.

Adolescent↗

A new treatment modality for fibromyalgia syndrome: hyperbaric oxygen therapy.

Fibromyalgia syndrome (FMS) is characterized by longstanding multifocal pain with generalized allodynia/hyperalgesia. There are several treatment methods but none has been specifically approved for this application. We conducted a randomized controlled study to evaluate the effect of hyperbaric oxygen (HBO) therapy in FMS (HBO group: n = 26; control group: n = 24). Tender points and pain threshold were assessed before, and after the first and fifteenth sessions of therapy. Pain was also scored on a visual analogue scale (VAS). There was a significant reduction in tender points and VAS scores and a significant increase in pain threshold of the HBO group after the first and fifteenth therapy sessions. There was also a significant difference between the HBO and control groups for all parameters except the VAS scores after the first session. We conclude that HBO therapy has an important role in managing FMS.

Adult↗

The effect of hyperbaric oxygen on intraocular pressure.

The effects of hyperoxia on intraocular pressure (IOP) have been studied in experiments on human beings and animals. The changes occurring in IOP in patients during routine HBO2 therapy are unknown. In this study we investigated IOP changes arising during the HBO2 therapy at 2.5 ATA. Fifty-six patients receiving HBO2 therapy for various reasons were included in the study. Bilateral IOPs of patients measured with the Tono-pen XL (Medtronic, Solan, USA) tonometer before, during and after HBO2 therapy. Average IOPs were 14.85 +/- 3.17 mmHg (range, 10-24), 13.00 +/- 2.97 mmHg (range, 9-21) and 14.74 +/- 3.12 mmHg (range, 10-22), respectively. IOP was reduced significantly during HBO2 therapy and returned its pre- HBO2 levels after therapy. Our data indicated a statistically significant decrease in IOPs during therapy at 2.5 ATA. This decrease was of minor physiological significance in these patients whose baseline IOP values were within the normal range.

Adult↗

On Turkey.

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Abortion, Induced↗

Improvements in mother-child health indicators in Turkey.

Turkey has a young population as a result of high fertility and growth rates in the recent past. Thirty-five percent of the population is less than 15 years of age, and 25 percent of the population comprises reproductive-age woman. The latest estimate of the population growth rate was 19 per thousand for the 1990-1995 period. In recent decades dramatic declines in fertility rates have been noted. In the early 1970s, the overall fertility rate was approximately five children per woman, declining to 2.7 in 1993. The crude birth rate is currently estimated to be approximately 23 per thousand. The crude death rate has also declined from approximately 30 per thousand in the 1940s to 6.5 per thousand in the 1990s. Life expectancy at birth in the Turkey is 65.9 for males and 70.5 for females. The infant mortality rate in the 1960s was approximately 200 per thousand, declining to 67 per thousand during the 1985-1990 period, and 53 per thousand for the period 1988-1993. It was 48 per thousand in 1995 and 42.2 per thousand in 1996, according to the State Planning Organization. The infant mortality rate has declined by 35 percent in the last ten years. The mortality rate for children under five years of age was 113.5 per thousand between 1978-1983 and 60.9 per thousand in 1993; it is currently 50 per thousand. The maternal mortality rate was greater than 200/100,000 in 1995. During the last five years the proportion of women receiving antenatal care has increased from 43 to 63 percent. The proportion of safe deliveries was 76 percent. Thirty-nine percent of all deliveries occur at home. The important point here is that the proportion of unsafe deliveries assisted by traditional birth attendants is 24 percent. It is very obvious that during the last 15 years, maternal and child health (MCH), especially child health, has improved dramatically in Turkey. The improvement made in the last five years has been more marked. The improvement is closely related to the government's special interest, attention and efforts to prevent and identify the most common health problems and to overcome these problems with appropriate interventions. The government also pays special attention to the socio-economic priority areas of the country and initiates special health programs in these areas first, in order to reduce high regional differences in MCH indices. Despite these dramatic improvements, one great obstacle is the high maternal and infant mortality and morbidity rates in the country at the time of ratification of the European Social Charter. The success made so for in maternal and child health should not be ignored, but it must be realized that much still remains to be done to improve the MCH level further.

Adolescent↗