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Biomedical subjects

A Aguado

Publications and source records attributed to A Aguado.

10 recordsLinked to original sources

[A comparative study of the evolution of caries in mentally retarded subjects of 5 years' duration].

OBJECTIVE: To study the evolution of caries in two groups of mentally retarded individuals. DESIGN: Longitudinal, prospective, non randomized study, with a five-years follow-up period, with intervention and control groups. SETTING: Community trial. Primary health care centre in Martorell. SUBJECTS: Mentally retarded individuals attending a workshop school (intervention group, N = 29) and living in a boarding school (control group, N = 25). INTERVENTION: One group was on a program of prevention and treatment of caries, the other one received the usual care and acted as a control group. MEASUREMENT AND MAIN RESULTS: The number of absent, filled and caries teeth were studied from 1992-1997. An analysis of the variance with repeated measures was carried out. The groups were comparable for most demographic characteristics and basal odontological parameters. While in the control group the number of caries increased (mean92 = 2.2; standard error [SE] = 0.5); mean97 = 3.3; SE = 0.5; p = 0.03) in the intervention group it did not change (mean92 = 1.8: SE = 0.4; mean97 = 1.7; SE = 0.2; p = 0.73). The variation over time was significantly different between the groups (p = 0.03). The mean of filled teeth increased in the intervention group (mean92 = 0.7; SE = 0.4; mean97 = 2.2; SE = 0.4; p < 0.0001) and it did not change in the control group (mean92 = 1.2; SE = 0.5; mean97 = 1.4; SE = 0.6; p = 0.48). There were statistical significant differences between the two groups in the variation over time (p = 0.017). CONCLUSIONS: Preventive and curative odontological intervention in mentally retarded individuals can be useful to improve the evolution of caries.

Adult

[Photochemotherapy in the treatment of oral erosive lichen planus. Letter].

Photochemotherapy with 8-methoxypsoralenes and PUVA has been found to be effective in the treatment of superficial skin inflammations, such as lichen planus. However, there is little bibliography on the treatment of oral lichen planus with PUVA. A case of oral erosive lichen planus was treated with oral psoralenes (0.6 mg/kg body weight) two hours before ultraviolet exposure. Twenty sessions were held, three weekly, for a total cumulative dose of 35.9 J/cm2. After treatment concluded, clinical symptoms and erosive lesions disappeared. PUVA therapy may be useful for severe forms of erosive oral lichen planus that do not respond to conventional treatment.

Drug Therapy

Assessment of dental students' ability to recognise precancerous lesions and conditions.

The role of dentists in both primary (promoting a healthier lifestyle) and secondary (early diagnosis) prevention of oral cancer is undeniable, and becomes particularly important as oral cancer is thought to be preceded by premalignant lesions or conditions in about one half of the cases. In these situations, there is the possibility for an early diagnosis which will definitively influence the survival rate. Thus, it is an undergraduate educational objective related to secondary prevention of oral cancer to increase the efficacy of screening of precancerous lesions/conditions. A questionnaire with 38 clinical cases including 16 benign lesions, 9 malignant lesions and 13 precancerous lesions or conditions was applied voluntarily to 3rd, 4th and 5th year University of Santiago de Compostela dental students on April 1996. The participation rate was 90% of the 3rd-year students, 60% in 4th-year class, and 50% of the 5th-year group. The agreement in the diagnosis with a panel of experts reached 81.45% for 5th-year students. Students of 3rd- and 4th-year scored lower percentages, probably due to the rarity of some of the conditions in our area. 5th-year students scored significantly higher values than 3rd- and 4th-year students.

Clinical Competence

[Barodontology: current status. Dental aspects].

We present a comprehensive review of barodontalgia, with reference to the several pathogenetic hypotheses, and insisting on the consideration of barodontalgia in the differential diagnosis of toothache. The odontologists approach to this increasing clinical problem is also discussed.

Aerospace Medicine

Gastroduodenal ulcer incidence in patients with venous thromboembolism.

The presence of peptic ulcer disease implies a high risk of bleeding in patients on heparin therapy. We reviewed our experience with 166 consecutive patients admitted because of venous thromboembolism. Of these 166 patients, 29 were referred for upper gastrointestinal endoscopy in order to detect the presence of any lesion that might contraindicate heparin therapy. A gastric ulcer was found in 10 patients, a duodenal ulcer in 11, and gastric erosions with signs of bleeding in 3 patients. Given the unexpectedly high frequency of ulcer in these patients, an upper gastrointestinal endoscopy was routinely performed early in the course of admission in 50 consecutive patients with venous thromboembolism. A gastric ulcer was found in 5 patients (10%), a duodenal ulcer in 7 (14%), and erosions in 2. Five of these patients had an unsuspected ulcer. A case can be made for prophylactic antiulcer therapy for all patients placed on anticoagulants for venous thromboembolism. Upper gastrointestinal endoscopy is indicated in patients with ulcer symptoms, in those with a previous history of peptic ulcer disease, and perhaps, in patients developing occult blood in the stools while on treatment with anticoagulants.

Adult

[Malignant angular cheilitis].

A case of chronic angular cheilitis is reported. Candida albicans was isolated repeatedly and the process developed into epitheliomatous carcinoma. The etiopathogenic role of Candida albicans and possible mechanism of action are discussed.

Aged