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Biomedical subjects

A Abraham

Publications and source records attributed to A Abraham.

157 records · Page 9Linked to original sources
PubMedDate not supplied

Comparative serological evaluation of avian influenza vaccine in turkeys.

Four- and six-week-old turkeys were vaccinated subcutaneously using avian influenza virus (AIV) A/Duck/613/MN/79 (H4N2) killed oil-emulsion vaccine. Sequential serological tests using agar gel precipitin (AGP), hemagglutination inhibition (HI), and enzyme-linked immunosorbent assay (ELISA) for measuring antibodies to AIV were performed up to 4 weeks postvaccination, when birds were challenged intranasally using A/Turkey/MN/80 (H4N2) live AIV. The ELISA was 25 to 1600 times more sensitive than the HI test and was able to detect antibody production earlier than the HI test. All turkeys with an ELISA titer of greater than or equal to 800 were protected against homologous challenge, as measured by virus recovery 3 days postchallenge. Four turkeys out of 20 serologically negative by AGP and HI tests but ELISA-positive were protected.

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PubMedDate not supplied

Evaluation of inactivated influenza vaccines in market turkeys.

The potency and efficacy of an inactivated oil-emulsion influenza vaccine against infection, illness, and virus shed was studied in market turkeys. No undesirable local or systemic reactions occurred following vaccination. The vaccine induced measurable antibody to nucleocapsid and hemagglutinin antigens of the virus. Challenged unvaccinated controls experienced airsacculitis, but none of the vaccinates were affected. The percent of the birds shedding virus following intranasal challenge was lower in the vaccinated groups than in the controls, and the quantity of virus shed was also smaller in vaccinated groups than in the controls.

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Thyroid carcinoma in children and adolescents.

Carcinoma of the thyroid gland, although fairly common in young adults, is uncommon in the first two decades of life. Because therapy is controversial, it is important to study a relatively large group of patients treated in a single department. This report records the findings and responses to treatment in 40 cases of thyroid gland carcinoma in children and adolescents treated from 1953 to 1982.

Adolescent↗
PubMedDate not supplied

Epizootiology of avian influenza--simultaneous monitoring of sentinel ducks and turkeys in Minnesota.

Isolation-reared mallards (Anas platyrhynchos) were placed on ponds in turkey-rearing areas in Minnesota, and their cloacae were periodically swabbed to attempt isolating virus from embryonated chicken eggs. Nearby turkeys were sampled by taking cloacal and tracheal swabs as well as blood samples. Hemagglutinating viruses were identified at the National Veterinary Services Laboratory, U.S. Department of Agriculture, Ames, Iowa. During this two-year study, the weekly influenza virus-isolation rate from ducks varied from 0 to 24.4%. A total of 213 influenza viruses were isolated from the ducks. Twenty-six influenza virus subtypes were detected. Ninety-seven flocks of turkeys were diagnosed as having influenza by virus isolation and/or serology. Eight influenza virus subtypes were involved in the turkey outbreaks, and seven of these were also detected in the ducks and/or other avian species. The weekly infection rate of the sentinel ducks correlated directly with observations of wild ducks at the monitoring sites. Influenza virus was isolated from water samples collected near the sentinel duck sites during the study.

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