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Biomedical subjects

A A Viru

Publications and source records attributed to A A Viru.

36 records · Page 2Linked to original sources
PubMedDate not supplied

[Adaptation of skeletal muscle and myocardium to increased motor activity in hypo- and athyroid rats].

Changes in contractility and synthesis of protein were studied in different types of muscles of hypo- and athyroid ratts during adaptation to physical exercise. Intensity of the exercises used corresponded to metabolic power output of 70% VO2max. Thyroidectomy caused a significant decrease in Mg2+ activated actomyosin ATPase activity and in content of RNA in myocardium and in fast oxidative-glycogenolytic and glycogenolytic skeletal muscle fibers. Exercises, intensity of which corresponded to metabolic power output of 70% VO2max led to a more distinct decrease in Mg2+ activated actomyosin ATPase activity in fast glycogenolytic muscle fibers, but in fast oxidative-glycogenolytic fibers the enzymatic activity was increased up to the level comparable with that of intact animals. Rhysical working capacity of athyroid rats was lower by 40% as compared with intact trained animals. Hypothyroidism, induced by means of administration of KJ into previously trained rats, caused a decrease in physical working capacity by 25%.

Actomyosin↗
PubMedDate not supplied

[Effect of corticosteroids on content of amino acids in liver tissue during muscular activity].

Metabolism of amino acids in the liver in connection with the adrenocortical functions of the adrenals was studied in rats as affected by 3-hour swimming. This load causes an increase in the content of corticosterone in blood, in the activity of alanine aminotranspherase as well as the decrease in the amount of free amino acids in the liver tissue. These changes are absent in adrenalectomized rats and appear again when corticosterone is administered to adrenalectomized animals before swimming.

Adrenalectomy↗